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Murcko scaffold

1-Benzoyl-4-(1-benzyl-4-piperidinyl)piperazine scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(c1ccccc1)N1CCN(C2CCN(Cc3ccccc3)CC2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzoyl-4-(1-benzyl-4-piperidinyl)piperazine page
Murcko scaffold O=C(c1ccccc1)N1CCN(C2CCN(Cc3ccccc3)CC2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3,5-dimethoxyphenyl)methanone chemical structure, C25H33N3O3, CAS 425390-17-6
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3,5-dimethoxyphenyl)methanone
CAS 425390-17-6C25H33N3O3
1-(1-Benzyl-4-piperidinyl)-4-{4-nitrobenzoyl}piperazine chemical structure, C23H28N4O3, CAS 444907-75-9
1-(1-Benzyl-4-piperidinyl)-4-{4-nitrobenzoyl}piperazine
CAS 444907-75-9C23H28N4O3
1-Benzoyl-4-(1-benzyl-4-piperidinyl)piperazine chemical structure, C23H29N3O, CAS 355395-94-7
1-Benzoyl-4-(1-benzyl-4-piperidinyl)piperazine
CAS 355395-94-7C23H29N3O
1-(1-Benzyl-4-piperidinyl)-4-(2-methoxybenzoyl)piperazine chemical structure, C24H31N3O2, CAS 461423-46-1
1-(1-Benzyl-4-piperidinyl)-4-(2-methoxybenzoyl)piperazine
CAS 461423-46-1C24H31N3O2
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-fluorophenyl)methanone chemical structure, C23H28FN3O, CAS 462604-30-4
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-fluorophenyl)methanone
CAS 462604-30-4C23H28FN3O
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-chlorophenyl)methanone chemical structure, C23H28ClN3O, CAS 423738-44-7
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-chlorophenyl)methanone
CAS 423738-44-7C23H28ClN3O
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(2-fluorophenyl)methanone chemical structure, C23H28FN3O, CAS 441314-70-1
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(2-fluorophenyl)methanone
CAS 441314-70-1C23H28FN3O
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone chemical structure, C26H35N3O4, CAS 425389-78-2
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
CAS 425389-78-2C26H35N3O4
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(2,3-dimethoxyphenyl)methanone chemical structure, C25H33N3O3, CAS 425391-25-9
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(2,3-dimethoxyphenyl)methanone
CAS 425391-25-9C25H33N3O3
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(4-fluorophenyl)methanone chemical structure, C23H28FN3O, CAS 353772-40-4
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(4-fluorophenyl)methanone
CAS 353772-40-4C23H28FN3O
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-methoxyphenyl)methanone chemical structure, C24H31N3O2, CAS 510718-55-5
[4-(1-Benzylpiperidin-4-yl)piperazin-1-yl]-(3-methoxyphenyl)methanone
CAS 510718-55-5C24H31N3O2
1-(1-Benzyl-4-piperidinyl)-4-(3,4-dimethoxybenzoyl)piperazine chemical structure, C25H33N3O3, CAS 441314-84-7
1-(1-Benzyl-4-piperidinyl)-4-(3,4-dimethoxybenzoyl)piperazine
CAS 441314-84-7C25H33N3O3