Murcko scaffold
Ring system with 5 rings and 26 atoms
27 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 26
- Chemicals
- 27
- With full pages
- 5
Scaffold SMILES
O=C1CC(c2ccccc2)Cc2c1cnc1c(-c3ccccc3)cnn21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 27 of 27 chemicals
![3-(4-Chlorophenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H18ClN3O, CAS 726199-63-9](/s/DOUDQFBMVNBDFJ-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 726199-63-9C23H18ClN3O
![2-Methyl-3-phenyl-8-(3,4,5-trimethoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C26H25N3O4, CAS 774561-23-8](/s/MTFLYONOCZOSAK-UHFFFAOYSA-N.svg)
2-Methyl-3-phenyl-8-(3,4,5-trimethoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-23-8C26H25N3O4
![8-(3,4-Dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H22FN3O3, CAS 876668-13-2](/s/ADPUTCZLQJJHFX-UHFFFAOYSA-N.svg)
8-(3,4-Dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 876668-13-2C25H22FN3O3
![2-Methyl-3,8-diphenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H19N3O, CAS 726199-97-9](/s/DPCFNOPUCQZUNN-UHFFFAOYSA-N.svg)
2-Methyl-3,8-diphenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 726199-97-9C23H19N3O
![8-(4-Chlorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H18ClN3O, CAS 726199-98-0](/s/GVJAPXUAFPNMJA-UHFFFAOYSA-N.svg)
8-(4-Chlorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 726199-98-0C23H18ClN3O
![8-(4-Isopropylphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C26H25N3O, CAS 774561-24-9](/s/OJXFPICAKRLPLM-UHFFFAOYSA-N.svg)
8-(4-Isopropylphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-24-9C26H25N3O
![8-(4-Fluorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H18FN3O, CAS 774561-25-0](/s/CBKQMJNERWYSPI-UHFFFAOYSA-N.svg)
8-(4-Fluorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-25-0C23H18FN3O
![8-(3,4-Dimethoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H23N3O3, CAS 774561-22-7](/s/KRKLIWZQEHVWOL-UHFFFAOYSA-N.svg)
8-(3,4-Dimethoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-22-7C25H23N3O3
![3-(4-Chlorophenyl)-8-(4-methoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C24H20ClN3O2, CAS 774561-29-4](/s/JYHNDASNQCXJPR-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-8-(4-methoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-29-4C24H20ClN3O2
![8-(4-Methoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C24H21N3O2, CAS 726199-99-1](/s/BXRDRFAACQWCQV-UHFFFAOYSA-N.svg)
8-(4-Methoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 726199-99-1C24H21N3O2
![8-(3-Chlorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H18ClN3O, CAS 774561-21-6](/s/RAXCDGDUNCFDRD-UHFFFAOYSA-N.svg)
8-(3-Chlorophenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 774561-21-6C23H18ClN3O
![3-(4-Fluorophenyl)-8-(4-methoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C24H20FN3O2, CAS 879623-71-9](/s/NCWVHMAMNWPEEY-UHFFFAOYSA-N.svg)
3-(4-Fluorophenyl)-8-(4-methoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 879623-71-9C24H20FN3O2
![3-(4-Chlorophenyl)-8-(2,4-dimethoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H22ClN3O3, CAS 879623-59-3](/s/IHRAWPYLZNIIIH-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-8-(2,4-dimethoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 879623-59-3C25H22ClN3O3
![3-(4-Methoxyphenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C24H21N3O2, CAS 896666-72-1](/s/IFGJHIVFCSCHCN-UHFFFAOYSA-N.svg)
3-(4-Methoxyphenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 896666-72-1C24H21N3O2
![3-(4-Fluorophenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C23H18FN3O, CAS 896666-16-3](/s/ZMFDKGQHQKLZGW-UHFFFAOYSA-N.svg)
3-(4-Fluorophenyl)-2-methyl-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 896666-16-3C23H18FN3O
![3-(4-Methoxyphenyl)-2-methyl-8-(4-methylphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H23N3O2, CAS 896666-75-4](/s/ZKSFBMXODUAUHI-UHFFFAOYSA-N.svg)
3-(4-Methoxyphenyl)-2-methyl-8-(4-methylphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 896666-75-4C25H23N3O2
![8-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H22ClN3O3, CAS 924874-55-5](/s/FQOZWGLULJVWSL-UHFFFAOYSA-N.svg)
8-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 924874-55-5C25H22ClN3O3
![3-(3-Chlorophenyl)-2-(methoxymethyl)-8-(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H22ClN3O3, CAS 932208-26-9](/s/CLPWOJAMQSNCPI-UHFFFAOYSA-N.svg)
3-(3-Chlorophenyl)-2-(methoxymethyl)-8-(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 932208-26-9C25H22ClN3O3
![8-(2,4-Dimethoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H23N3O3, CAS 896666-55-0](/s/KWYJQTHJILLJRJ-UHFFFAOYSA-N.svg)
8-(2,4-Dimethoxyphenyl)-2-methyl-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 896666-55-0C25H23N3O3
![2-(Methoxymethyl)-3,8-diphenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C24H21N3O2, CAS 925169-60-4](/s/MXGRNQYKNYGWCN-UHFFFAOYSA-N.svg)
2-(Methoxymethyl)-3,8-diphenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 925169-60-4C24H21N3O2
![2-(Methoxymethyl)-8-(4-methoxyphenyl)-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H23N3O3, CAS 925144-68-9](/s/KJGQMDZNOCFCSF-UHFFFAOYSA-N.svg)
2-(Methoxymethyl)-8-(4-methoxyphenyl)-3-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 925144-68-9C25H23N3O3
![2-(Methoxymethyl)-3-(4-methoxyphenyl)-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H23N3O3, CAS 925574-22-7](/s/PMKOCBPRMKDDCY-UHFFFAOYSA-N.svg)
2-(Methoxymethyl)-3-(4-methoxyphenyl)-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 925574-22-7C25H23N3O3
![2-(Methoxymethyl)-3,8-bis(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C26H25N3O4, CAS 932208-22-5](/s/BOXYZIQUBKXFBY-UHFFFAOYSA-N.svg)
2-(Methoxymethyl)-3,8-bis(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 932208-22-5C26H25N3O4
![8-(3-Chlorophenyl)-2-(methoxymethyl)-3-(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one chemical structure, C25H22ClN3O3, CAS 932178-07-9](/s/XXPNULXAIFBYAU-UHFFFAOYSA-N.svg)
8-(3-Chlorophenyl)-2-(methoxymethyl)-3-(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
CAS 932178-07-9C25H22ClN3O3
- 3-(3-Chlorophenyl)-2-(methoxymethyl)-8-phenyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one932254-41-6C24H20ClN3O2
- 3-(3-Chlorophenyl)-8-(3,4-dimethoxyphenyl)-2-(methoxymethyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one932208-28-1C26H24ClN3O4
- 8-(2,4-Dimethoxyphenyl)-2-(methoxymethyl)-3-(4-methoxyphenyl)-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one1030553-77-5C27H27N3O5