Murcko scaffold
Ring system with 2 rings and 22 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 22
- Chemicals
- 10
- With full pages
- 2
Scaffold SMILES
O=C1CCCCCCC=CCC(C=CC=CCCC2CO2)O1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
FD-895
CAS 147025-57-8C31H50O9
RefChem:1050508
CAS 445493-23-2C30H48O8
Pladienolide a
CAS 445493-22-1C28H46O7
A6Fdp4xds3
CAS 1228183-92-3C31H50O9
Rebecsinib (17S-FD-895)
C31H50O9
![[7,10-Dihydroxy-2-[7-hydroxy-7-[3-(3-methoxypentan-2-yl)oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1-oxacyclododec-4-en-6-yl] acetate chemical structure, C31H50O9, CAS 464185-11-3](/s/LDCZLUDGHYDTHV-UHFFFAOYSA-N.svg)
[7,10-Dihydroxy-2-[7-hydroxy-7-[3-(3-methoxypentan-2-yl)oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1-oxacyclododec-4-en-6-yl] acetate
CAS 464185-11-3C31H50O9
![(4R,7R,8S,9E,11S,12S)-4,7,8-Trihydroxy-12-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-7,11-dimethyl-1-oxacyclododec-9-en-2-one chemical structure, C28H46O8, CAS 445493-26-5](/s/UVGNDKLNNFHGQG-WEPDMDDFSA-N.svg)
(4R,7R,8S,9E,11S,12S)-4,7,8-Trihydroxy-12-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-7,11-dimethyl-1-oxacyclododec-9-en-2-one
CAS 445493-26-5C28H46O8
Orb2815017
CAS 2803326-64-7C31H50O9
Orb2945658
CAS 2598242-04-5C31H50O9
Rebecsinib
C31H50O9