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Murcko scaffold

Ring system with 4 rings and 22 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
16
With full pages
12
Scaffold SMILES

O=c1[nH]c(=O)c2c(nc3n2CC(COc2ccccc2)O3)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(=O)c2c(nc3n2CC(COc2ccccc2)O3)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-ME-7-((2-ME-Phenoxy)ME)-6,7-dihydro(1,3)oxazolo(2,3-F)purine-2,4(1H,3H)-dione chemical structure, C16H16N4O4, CAS 332384-52-8
1-ME-7-((2-ME-Phenoxy)ME)-6,7-dihydro(1,3)oxazolo(2,3-F)purine-2,4(1H,3H)-dione
CAS 332384-52-8C16H16N4O4
1,3-Dimethyl-7-((p-tolyloxy)methyl)-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C17H18N4O4, CAS 850236-42-9
1,3-Dimethyl-7-((p-tolyloxy)methyl)-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 850236-42-9C17H18N4O4
1-Methyl-7-(phenoxymethyl)-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C15H14N4O4, CAS 301353-87-7
1-Methyl-7-(phenoxymethyl)-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 301353-87-7C15H14N4O4
7-((4-Methoxyphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C17H18N4O5, CAS 333752-22-0
7-((4-Methoxyphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 333752-22-0C17H18N4O5
7-((4-Methoxyphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C16H16N4O5, CAS 333752-27-5
7-((4-Methoxyphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 333752-27-5C16H16N4O5
1-Methyl-7-p-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione chemical structure, C16H16N4O4, CAS 876890-75-4
1-Methyl-7-p-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione
CAS 876890-75-4C16H16N4O4
7-((4-CL-Phenoxy)ME)-1-ME-6,7-dihydro(1,3)oxazolo(2,3-F)purine-2,4(1H,3H)-dione chemical structure, C15H13ClN4O4, CAS 332384-51-7
7-((4-CL-Phenoxy)ME)-1-ME-6,7-dihydro(1,3)oxazolo(2,3-F)purine-2,4(1H,3H)-dione
CAS 332384-51-7C15H13ClN4O4
1-Methyl-7-m-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione chemical structure, C16H16N4O4, CAS 879071-29-1
1-Methyl-7-m-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione
CAS 879071-29-1C16H16N4O4
7-((3,4-Dimethylphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C18H20N4O4, CAS 879071-36-0
7-((3,4-Dimethylphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 879071-36-0C18H20N4O4
7-((3-Ethylphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C17H18N4O4, CAS 879071-39-3
7-((3-Ethylphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 879071-39-3C17H18N4O4
7-((3-Ethylphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C18H20N4O4, CAS 879071-43-9
7-((3-Ethylphenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 879071-43-9C18H20N4O4
7-((4-Ethylphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C17H18N4O4, CAS 879071-47-3
7-((4-Ethylphenoxy)methyl)-1-methyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 879071-47-3C17H18N4O4
1,3-Dimethyl-7-phenoxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione chemical structure, C16H16N4O4, CAS 78960-54-0
1,3-Dimethyl-7-phenoxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione
CAS 78960-54-0C16H16N4O4
1,3-Dimethyl-7-o-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione chemical structure, C17H18N4O4, CAS 752260-45-0
1,3-Dimethyl-7-o-tolyloxymethyl-6,7-dihydro-1H-oxazolo[2,3-f]purine-2,4-dione
CAS 752260-45-0C17H18N4O4
7-((4-Chlorophenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C16H15ClN4O4, CAS 879071-51-9
7-((4-Chlorophenoxy)methyl)-1,3-dimethyl-6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 879071-51-9C16H15ClN4O4
Methyl 2-(7-((4-chlorophenoxy)methyl)-1-methyl-2,4-dioxo-1,2,6,7-tetrahydrooxazolo[2,3-f]purin-3(4H)-yl)acetate chemical structure, C18H17ClN4O6, CAS 1203397-29-8
Methyl 2-(7-((4-chlorophenoxy)methyl)-1-methyl-2,4-dioxo-1,2,6,7-tetrahydrooxazolo[2,3-f]purin-3(4H)-yl)acetate
CAS 1203397-29-8C18H17ClN4O6