Murcko scaffold
Ring system with 5 rings and 28 atoms
22 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 22
- With full pages
- 10
Scaffold SMILES
O=S(=O)(c1ccccc1)c1nnn2c1nc(N1CCCCC1)c1ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 22 of 22 chemicals
![3-(Benzenesulfonyl)-5-(4-methylpiperidin-1-yl)triazolo[1,5-a]quinazoline chemical structure, C21H21N5O2S, CAS 866589-13-1](/s/BDDNRZZGCQJYLK-UHFFFAOYSA-N.svg)
3-(Benzenesulfonyl)-5-(4-methylpiperidin-1-yl)triazolo[1,5-a]quinazoline
CAS 866589-13-1C21H21N5O2S
![1-[7-Chloro-3-(4-ethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]-4-methylpiperidine chemical structure, C23H24ClN5O2S, CAS 904581-97-1](/s/GEIGJRHAFKZXJO-UHFFFAOYSA-N.svg)
1-[7-Chloro-3-(4-ethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]-4-methylpiperidine
CAS 904581-97-1C23H24ClN5O2S
![1-[7-Chloro-3-(4-ethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]-3-methylpiperidine chemical structure, C23H24ClN5O2S, CAS 904582-01-0](/s/LIJZWTVWRGURPD-UHFFFAOYSA-N.svg)
1-[7-Chloro-3-(4-ethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]-3-methylpiperidine
CAS 904582-01-0C23H24ClN5O2S
![1-[7-Chloro-3-(3,4-dimethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxamide chemical structure, C23H23ClN6O3S, CAS 904583-27-3](/s/SSVJUEGVVUMQMV-UHFFFAOYSA-N.svg)
1-[7-Chloro-3-(3,4-dimethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxamide
CAS 904583-27-3C23H23ClN6O3S
![Ethyl 1-(7-chloro-3-((4-ethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxylate chemical structure, C25H26ClN5O4S, CAS 893788-80-2](/s/DTLFTOVNXQIWQE-UHFFFAOYSA-N.svg)
Ethyl 1-(7-chloro-3-((4-ethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxylate
CAS 893788-80-2C25H26ClN5O4S
![Ethyl 1-(7-chloro-3-((3,4-dimethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-3-carboxylate chemical structure, C25H26ClN5O4S, CAS 893789-57-6](/s/UXHQKCSNIPDLFV-UHFFFAOYSA-N.svg)
Ethyl 1-(7-chloro-3-((3,4-dimethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-3-carboxylate
CAS 893789-57-6C25H26ClN5O4S
![Ethyl 1-[7-chloro-3-(3,4-dimethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxylate chemical structure, C25H26ClN5O4S, CAS 893788-75-5](/s/OPBHFQKQEBTAKA-UHFFFAOYSA-N.svg)
Ethyl 1-[7-chloro-3-(3,4-dimethylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxylate
CAS 893788-75-5C25H26ClN5O4S
![1-[3-(Benzenesulfonyl)triazolo[1,5-a]quinazolin-5-yl]piperidine-4-carboxamide chemical structure, C21H20N6O3S, CAS 893274-52-7](/s/RVFJDZMGSICQGO-UHFFFAOYSA-N.svg)
1-[3-(Benzenesulfonyl)triazolo[1,5-a]quinazolin-5-yl]piperidine-4-carboxamide
CAS 893274-52-7C21H20N6O3S
![1-[3-(4-Bromobenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxamide chemical structure, C21H19BrN6O3S, CAS 895649-05-5](/s/BQZHXJGHEVTNRK-UHFFFAOYSA-N.svg)
1-[3-(4-Bromobenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxamide
CAS 895649-05-5C21H19BrN6O3S
![1-(3-Tosyl-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxamide chemical structure, C22H22N6O3S, CAS 893272-25-8](/s/UBKYBQPVDVPOCY-UHFFFAOYSA-N.svg)
1-(3-Tosyl-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxamide
CAS 893272-25-8C22H22N6O3S
![Ethyl 1-[3-(benzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxylate chemical structure, C23H23N5O4S, CAS 893273-35-3](/s/JPSQHJFASXXQMD-UHFFFAOYSA-N.svg)
Ethyl 1-[3-(benzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine-4-carboxylate
CAS 893273-35-3C23H23N5O4S
![Ethyl 1-[3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazolin-5-yl]piperidine-3-carboxylate chemical structure, C23H23N5O4S, CAS 893274-21-0](/s/JWCXJGNKSIAFBR-UHFFFAOYSA-N.svg)
Ethyl 1-[3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazolin-5-yl]piperidine-3-carboxylate
CAS 893274-21-0C23H23N5O4S
![Ethyl 1-{3-[4-(propan-2-yl)benzenesulfonyl]-[1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-4-carboxylate chemical structure, C26H29N5O4S, CAS 892275-63-7](/s/IPSVSHJRSLELRE-UHFFFAOYSA-N.svg)
Ethyl 1-{3-[4-(propan-2-yl)benzenesulfonyl]-[1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-4-carboxylate
CAS 892275-63-7C26H29N5O4S
![Ethyl 1-{3-[4-(propan-2-yl)benzenesulfonyl]-[1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate chemical structure, C26H29N5O4S, CAS 892276-03-8](/s/JTVUZKDISZEMPX-UHFFFAOYSA-N.svg)
Ethyl 1-{3-[4-(propan-2-yl)benzenesulfonyl]-[1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate
CAS 892276-03-8C26H29N5O4S
![Ethyl 1-(3-((4-bromophenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-3-carboxylate chemical structure, C23H22BrN5O4S, CAS 895640-33-2](/s/IPVNMKXONMVFSX-UHFFFAOYSA-N.svg)
Ethyl 1-(3-((4-bromophenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-3-carboxylate
CAS 895640-33-2C23H22BrN5O4S
![Ethyl 1-(3-((4-bromophenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxylate chemical structure, C23H22BrN5O4S, CAS 895640-37-6](/s/DHXOZJAADWMJSB-UHFFFAOYSA-N.svg)
Ethyl 1-(3-((4-bromophenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-yl)piperidine-4-carboxylate
CAS 895640-37-6C23H22BrN5O4S
![Ethyl 1-{3-[(4-methylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate chemical structure, C24H25N5O4S, CAS 893271-97-1](/s/FFMMNMCIGIEFBM-UHFFFAOYSA-N.svg)
Ethyl 1-{3-[(4-methylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate
CAS 893271-97-1C24H25N5O4S
![Ethyl 1-{3-[(3,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate chemical structure, C25H27N5O4S, CAS 893276-44-3](/s/XYWGAERHIGHCPC-UHFFFAOYSA-N.svg)
Ethyl 1-{3-[(3,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-3-carboxylate
CAS 893276-44-3C25H27N5O4S
![1-{3-[(3,4-Dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-4-carboxamide chemical structure, C23H24N6O3S, CAS 893276-72-7](/s/PMBIASQKKYNLFP-UHFFFAOYSA-N.svg)
1-{3-[(3,4-Dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-yl}piperidine-4-carboxamide
CAS 893276-72-7C23H24N6O3S
![7-Chloro-5-(2-methylpiperidin-1-yl)-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazoline chemical structure, C21H20ClN5O2S, CAS 904580-80-9](/s/IXGBELJCALLGHW-UHFFFAOYSA-N.svg)
7-Chloro-5-(2-methylpiperidin-1-yl)-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazoline
CAS 904580-80-9C21H20ClN5O2S
![3-Methyl-1-[3-(4-methylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine chemical structure, C22H23N5O2S, CAS 904585-95-1](/s/WOICAJJPSZXHRP-UHFFFAOYSA-N.svg)
3-Methyl-1-[3-(4-methylbenzenesulfonyl)-[1,2,3]triazolo[1,5-A]quinazolin-5-yl]piperidine
CAS 904585-95-1C22H23N5O2S
![7-Chloro-5-(3-methylpiperidin-1-yl)-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazoline chemical structure, C21H20ClN5O2S, CAS 904580-16-1](/s/DIAKNZDCBQINED-UHFFFAOYSA-N.svg)
7-Chloro-5-(3-methylpiperidin-1-yl)-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazoline
CAS 904580-16-1C21H20ClN5O2S