Murcko scaffold
Ring system with 5 rings and 27 atoms
19 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 27
- Chemicals
- 19
- With full pages
- 3
Scaffold SMILES
O=C1CCCC2=C1C(c1ccc(-c3ccccc3)o1)Nc1ccccc1N2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
![6-[5-(4-Bromophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one chemical structure, C25H23BrN2O2, CAS 419544-88-0](/s/IVYTWYDQSTVDGF-UHFFFAOYSA-N.svg)
6-[5-(4-Bromophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
CAS 419544-88-0C25H23BrN2O2
![9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-(2,2,2-trifluoroacetyl)-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C27H22F3N3O5, CAS 354543-97-8](/s/LFZVAWWJVWKVOV-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-(2,2,2-trifluoroacetyl)-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 354543-97-8C27H22F3N3O5
![9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one chemical structure, C25H23N3O4, CAS 312621-65-1](/s/VJTJLCNHVVRRIN-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
CAS 312621-65-1C25H23N3O4
![6-[5-(4-Bromophenyl)furan-2-yl]-9,9-dimethyl-5-(2,2,2-trifluoroacetyl)-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C27H22BrF3N2O3, CAS 354543-69-4](/s/OEPZZARIWJQQPW-UHFFFAOYSA-N.svg)
6-[5-(4-Bromophenyl)furan-2-yl]-9,9-dimethyl-5-(2,2,2-trifluoroacetyl)-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 354543-69-4C27H22BrF3N2O3
![9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-pentanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C30H31N3O5, CAS 312621-18-4](/s/MOBCATQFZRZFEZ-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-pentanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 312621-18-4C30H31N3O5
![9,9-Dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C28H27N3O5, CAS 354537-15-8](/s/XOQCXPLBVAENSH-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 354537-15-8C28H27N3O5
![9,9-Dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C28H27N3O5, CAS 406914-81-6](/s/SVAPJUOFTYQPFQ-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 406914-81-6C28H27N3O5
![5-Acetyl-9,9-dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C27H25N3O5, CAS 352693-45-9](/s/KBBYLZOEDSNLOJ-UHFFFAOYSA-N.svg)
5-Acetyl-9,9-dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 352693-45-9C27H25N3O5
![9,9-Dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one chemical structure, C25H23N3O4, CAS 369401-80-9](/s/RPVNPNHAAGEORV-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
CAS 369401-80-9C25H23N3O4
![9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C28H27N3O5, CAS 312621-31-1](/s/QRFXZPVMQWAOJM-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(4-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 312621-31-1C28H27N3O5
![9,9-Dimethyl-6-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C29H29N3O5, CAS 369403-90-7](/s/IBPWICYXVHFGOD-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 369403-90-7C29H29N3O5
![9,9-Dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one chemical structure, C25H23N3O4, CAS 312621-79-7](/s/TYJRQKLPFPQHDD-UHFFFAOYSA-N.svg)
9,9-Dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
CAS 312621-79-7C25H23N3O4
![6-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one chemical structure, C25H22ClN3O4, CAS 337503-16-9](/s/BFFIHJNGSJKSED-UHFFFAOYSA-N.svg)
6-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
CAS 337503-16-9C25H22ClN3O4
![3-[5-(5-Acetyl-9,9-dimethyl-7-oxo-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-6-yl)furan-2-yl]benzoic acid chemical structure, C28H26N2O5, CAS 312621-87-7](/s/NWNZNPKRSXQYGO-UHFFFAOYSA-N.svg)
3-[5-(5-Acetyl-9,9-dimethyl-7-oxo-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-6-yl)furan-2-yl]benzoic acid
CAS 312621-87-7C28H26N2O5
![5-Acetyl-9,9-dimethyl-6-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C28H27N3O5, CAS 337503-28-3](/s/YQLJEIWWIBVFLM-UHFFFAOYSA-N.svg)
5-Acetyl-9,9-dimethyl-6-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 337503-28-3C28H27N3O5
![5-Acetyl-6-[5-(2-chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C27H24ClN3O5, CAS 337503-18-1](/s/HGGLKSMWCUHTPK-UHFFFAOYSA-N.svg)
5-Acetyl-6-[5-(2-chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 337503-18-1C27H24ClN3O5
![6-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C28H26ClN3O5, CAS 353772-52-8](/s/BHBMABIGFAVFKB-UHFFFAOYSA-N.svg)
6-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-9,9-dimethyl-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 353772-52-8C28H26ClN3O5
![9,9-Dimethyl-5-(2-methylpropanoyl)-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C29H29N3O5, CAS 351163-07-0](/s/SDBRMROCHBVHGM-UHFFFAOYSA-N.svg)
9,9-Dimethyl-5-(2-methylpropanoyl)-6-[5-(3-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 351163-07-0C29H29N3O5
![5-Acetyl-9,9-dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C27H25N3O5, CAS 353787-22-1](/s/FOYAGCWCFXBYNI-UHFFFAOYSA-N.svg)
5-Acetyl-9,9-dimethyl-6-[5-(2-nitrophenyl)furan-2-yl]-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one
CAS 353787-22-1C27H25N3O5