Murcko scaffold

4-Piperidin-1-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine scaffold

21 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 19
Chemicals: 21
With full pages: 2

Scaffold SMILES

c1nc(N2CCCCC2)c2c3c(sc2n1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-Piperidin-1-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine page

Murcko scaffold c1nc(N2CCCCC2)c2c3c(sc2n1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

4-Piperidin-1-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine

CAS 40277-54-1C₁₅H₁₉N₃S

4-(4-Methylpiperidino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

CAS 303793-38-6C₁₆H₂₁N₃S

1-(5,6,7,8-Tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid

CAS 602293-26-5C₁₆H₁₉N₃O₂S

7-Methyl-4-(4-methylpiperidin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine

CAS 315682-06-5C₁₇H₂₃N₃S

4-(3-Methylpiperidin-1-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine hydrochloride

CAS 1049713-85-0C₁₆H₂₂ClN₃S

2,7-Dimethyl-4-(4-methylpiperidin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

CAS 379245-42-8C₁₈H₂₅N₃S

4-(3,5-Dimethylpiperidin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

CAS 433260-35-6C₁₇H₂₃N₃S

7-Methyl-4-(1-piperidinyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

CAS 450395-05-8C₁₆H₂₁N₃S

4-(2-Methylpiperidin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine

CAS 379239-48-2C₁₆H₂₁N₃S

$3-(3,5-Dimethylpiperidin-1-yl)-5-methyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5-tetraene chemical structure, C18H25N3S, CAS 423143-27-5$

3-(3,5-Dimethylpiperidin-1-yl)-5-methyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5-tetraene

CAS 423143-27-5C₁₈H₂₅N₃S

N-[1-(2-Methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanesulfonamide

CAS 2877667-66-6C₁₇H₂₄N₄O₂S₂

Methyl N-{[1-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperidin-3-yl]carbonyl}glycinate

CAS 1219556-36-1C₁₉H₂₄N₄O₃S

N-(3-Methoxypropyl)-1-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperidine-3-carboxamide

CAS 1219580-02-5C₂₀H₂₈N₄O₂S

N-(2-Methoxyethyl)-1-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

CAS 1219588-47-2C₁₉H₂₆N₄O₂S

Methyl 2-({[1-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)-4-piperidyl]carbonyl}amino)acetate

CAS 1206111-24-1C₁₉H₂₄N₄O₃S

N-[1-(2-Methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]methanesulfonamide

CAS 2770643-54-2C₁₇H₂₄N₄O₂S₂

$N-(1-{5,11-Dimethyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraen-3-yl}piperidin-4-yl)methanesulfonamide chemical structure, C18H26N4O2S2, CAS 2877630-82-3$

N-(1-{5,11-Dimethyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraen-3-yl}piperidin-4-yl)methanesulfonamide

CAS 2877630-82-3C₁₈H₂₆N₄O₂S₂

$1,3,3-Trimethyl-1-(1-{5-methyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraen-3-yl}piperidin-4-yl)urea chemical structure, C20H29N5OS, CAS 2877691-30-8$

1,3,3-Trimethyl-1-(1-{5-methyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraen-3-yl}piperidin-4-yl)urea

CAS 2877691-30-8C₂₀H₂₉N₅OS

$N-Methyl-N-(1-{5-methyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraen-3-yl}piperidin-3-yl)methanesulfonamide chemical structure, C18H26N4O2S2, CAS 2877648-08-1$