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Murcko scaffold

5,6,7,8-Tetrahydro-4-(1-piperazinyl)(1)benzothieno(2,3-d)pyrimidine scaffold

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
14
With full pages
5
Scaffold SMILES

c1nc(N2CCNCC2)c2c3c(sc2n1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydro-4-(1-piperazinyl)(1)benzothieno(2,3-d)pyrimidine page
Murcko scaffold c1nc(N2CCNCC2)c2c3c(sc2n1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-{8-Thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6-tetraen-3-yl}piperazine-1-carbaldehyde chemical structure, C15H18N4OS, CAS 370071-21-9
4-{8-Thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6-tetraen-3-yl}piperazine-1-carbaldehyde
CAS 370071-21-9C15H18N4OS
2-[4-(5,6,7,8-Tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]acetonitrile chemical structure, C16H19N5S, CAS 683797-08-2
2-[4-(5,6,7,8-Tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]acetonitrile
CAS 683797-08-2C16H19N5S
2-Ethyl-4-(4-ethylpiperazino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine chemical structure, C18H26N4S, CAS 315682-89-4
2-Ethyl-4-(4-ethylpiperazino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine
CAS 315682-89-4C18H26N4S
2-Methyl-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine chemical structure, C16H22N4S, CAS 313515-54-7
2-Methyl-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
CAS 313515-54-7C16H22N4S
4-(4-Ethylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine chemical structure, C16H22N4S, CAS 433964-98-8
4-(4-Ethylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
CAS 433964-98-8C16H22N4S
2-[4-(7-Methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol chemical structure, C17H24N4OS, CAS 449192-64-7
2-[4-(7-Methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol
CAS 449192-64-7C17H24N4OS
4-(4-Methylpiperazin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine chemical structure, C15H20N4S, CAS 317330-32-8
4-(4-Methylpiperazin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine
CAS 317330-32-8C15H20N4S
6-Methyl-4-[4-(2-methylprop-2-en-1-yl)piperazin-1-yl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine chemical structure, C19H26N4S, CAS 433256-62-3
6-Methyl-4-[4-(2-methylprop-2-en-1-yl)piperazin-1-yl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine
CAS 433256-62-3C19H26N4S
2-[4-(6-Methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol chemical structure, C17H24N4OS, CAS 384797-12-0
2-[4-(6-Methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol
CAS 384797-12-0C17H24N4OS
6-(2-Methylbutan-2-yl)-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine chemical structure, C20H30N4S, CAS 433319-62-1
6-(2-Methylbutan-2-yl)-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
CAS 433319-62-1C20H30N4S
6-Methyl-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine chemical structure, C16H22N4S, CAS 612523-29-2
6-Methyl-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine
CAS 612523-29-2C16H22N4S
2,7-Dimethyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine chemical structure, C16H22N4S, CAS 824414-51-9
2,7-Dimethyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine
CAS 824414-51-9C16H22N4S
2-Ethyl-4-piperazin-1-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine chemical structure, C16H22N4S, CAS 606114-08-3
2-Ethyl-4-piperazin-1-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
CAS 606114-08-3C16H22N4S
5,6,7,8-Tetrahydro-4-(1-piperazinyl)(1)benzothieno(2,3-d)pyrimidine chemical structure, C14H18N4S, CAS 245449-99-4
5,6,7,8-Tetrahydro-4-(1-piperazinyl)(1)benzothieno(2,3-d)pyrimidine
CAS 245449-99-4C14H18N4S