Murcko scaffold
4-Cbz-aminopiperidine scaffold
199 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 17
- Chemicals
- 199
- With full pages
- 4
Scaffold SMILES
O=C(NC1CCNCC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 199 chemicals
![[1-(2-Amino-ethyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester chemical structure, C17H27N3O2, CAS 1353976-79-0](/s/LLLLBJZPJLQWRZ-UHFFFAOYSA-N.svg)
[1-(2-Amino-ethyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
CAS 1353976-79-0C17H27N3O2
![[1-(2-Amino-ethyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester chemical structure, C18H29N3O2, CAS 1353943-94-8](/s/XIKMZQVLLPJIME-UHFFFAOYSA-N.svg)
[1-(2-Amino-ethyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester
CAS 1353943-94-8C18H29N3O2
![[1-(2-Chloro-acetyl)-piperidin-4-yl]-carbamic acid benzyl ester chemical structure, C15H19ClN2O3, CAS 1353962-27-2](/s/WGKLRGGJFKIRTL-UHFFFAOYSA-N.svg)
[1-(2-Chloro-acetyl)-piperidin-4-yl]-carbamic acid benzyl ester
CAS 1353962-27-2C15H19ClN2O3
![[1-(2-Chloro-acetyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester chemical structure, C16H21ClN2O3, CAS 1353953-92-0](/s/BFOWFVXVMDUOCH-UHFFFAOYSA-N.svg)
[1-(2-Chloro-acetyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester
CAS 1353953-92-0C16H21ClN2O3
![[1-(2-Chloro-acetyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester chemical structure, C17H23ClN2O3, CAS 1353981-58-4](/s/MVJGHDLZOIFYLH-UHFFFAOYSA-N.svg)
[1-(2-Chloro-acetyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
CAS 1353981-58-4C17H23ClN2O3
![[1-(2-Chloro-acetyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester chemical structure, C18H25ClN2O3, CAS 1353973-61-1](/s/NIJMVKCPVLJQIB-UHFFFAOYSA-N.svg)
[1-(2-Chloro-acetyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester
CAS 1353973-61-1C18H25ClN2O3
![[1-(2-Amino-acetyl)-piperidin-4-yl]-carbamic acid benzyl ester chemical structure, C15H21N3O3, CAS 1353977-19-1](/s/VZBUISWPKRGQRO-UHFFFAOYSA-N.svg)
[1-(2-Amino-acetyl)-piperidin-4-yl]-carbamic acid benzyl ester
CAS 1353977-19-1C15H21N3O3
![[1-(2-Amino-acetyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester chemical structure, C16H23N3O3, CAS 1353957-50-2](/s/KSXCIYMFVWEWGL-UHFFFAOYSA-N.svg)
[1-(2-Amino-acetyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester
CAS 1353957-50-2C16H23N3O3
![[1-(2-Amino-acetyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester chemical structure, C17H25N3O3, CAS 1353982-56-5](/s/PVMJIULOKIQMBN-UHFFFAOYSA-N.svg)
[1-(2-Amino-acetyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
CAS 1353982-56-5C17H25N3O3
![[1-(2-Amino-acetyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester chemical structure, C18H27N3O3, CAS 1353975-05-9](/s/VIDGPTPAJQLEMY-UHFFFAOYSA-N.svg)
[1-(2-Amino-acetyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester
CAS 1353975-05-9C18H27N3O3
![[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-carbamic acid benzyl ester chemical structure, C16H23N3O3, CAS 1354017-57-4](/s/YXKOACTUHVBKSQ-LBPRGKRZSA-N.svg)
[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-carbamic acid benzyl ester
CAS 1354017-57-4C16H23N3O3
![[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester chemical structure, C17H25N3O3, CAS 1354016-53-7](/s/WJZOYBADOXBNHO-ZDUSSCGKSA-N.svg)
[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester
CAS 1354016-53-7C17H25N3O3
![[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester chemical structure, C18H27N3O3, CAS 1353993-60-8](/s/VOZLTXSTLXMXDS-AWEZNQCLSA-N.svg)
[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
CAS 1353993-60-8C18H27N3O3
![[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester chemical structure, C19H29N3O3, CAS 1354016-48-0](/s/IOVRNRKHBNRLDV-HNNXBMFYSA-N.svg)
[1-((S)-2-Amino-propionyl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester
CAS 1354016-48-0C19H29N3O3
![[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-carbamic acid benzyl ester chemical structure, C18H27N3O3, CAS 1354007-37-6](/s/NWDZJCVJRLHSSM-INIZCTEOSA-N.svg)
[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-carbamic acid benzyl ester
CAS 1354007-37-6C18H27N3O3
![[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester chemical structure, C19H29N3O3, CAS 155455-92-8](/s/CUPHKRMNRSKKGI-KRWDZBQOSA-N.svg)
[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester
CAS 155455-92-8C19H29N3O3
![[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester chemical structure, C20H31N3O3, CAS 1354009-46-3](/s/AJWUBGGFYVEWQY-SFHVURJKSA-N.svg)
[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
CAS 1354009-46-3C20H31N3O3
![[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester chemical structure, C21H33N3O3, CAS 1354000-72-8](/s/GBBPEJLUCIVHRH-IBGZPJMESA-N.svg)
[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester
CAS 1354000-72-8C21H33N3O3
(4-Benzyloxycarbonylamino-piperidin-1-yl)-acetic acid
CAS 1353954-30-9C15H20N2O4
![[4-(Benzyloxycarbonyl-methyl-amino)-piperidin-1-yl]-acetic acid chemical structure, C16H22N2O4, CAS 1353947-11-1](/s/WUIXMTPSUWZSFE-UHFFFAOYSA-N.svg)
[4-(Benzyloxycarbonyl-methyl-amino)-piperidin-1-yl]-acetic acid
CAS 1353947-11-1C16H22N2O4
![[4-(Benzyloxycarbonyl-ethyl-amino)-piperidin-1-yl]-acetic acid chemical structure, C17H24N2O4, CAS 1353975-08-2](/s/SKWYXDYVLCRYSZ-UHFFFAOYSA-N.svg)
[4-(Benzyloxycarbonyl-ethyl-amino)-piperidin-1-yl]-acetic acid
CAS 1353975-08-2C17H24N2O4
![[4-(Benzyloxycarbonyl-isopropyl-amino)-piperidin-1-yl]-acetic acid chemical structure, C18H26N2O4, CAS 1353962-47-6](/s/HWUUIDSGDIAZAE-UHFFFAOYSA-N.svg)
[4-(Benzyloxycarbonyl-isopropyl-amino)-piperidin-1-yl]-acetic acid
CAS 1353962-47-6C18H26N2O4
Benzyl (4-(fluoromethyl)piperidin-4-yl)carbamate
CAS 1187321-35-2C14H19FN2O2
![tert-Butyl (3S,4S)-4-{[(benzyloxy)carbonyl]amino}-3-hydroxypiperidine-1-carboxylate chemical structure, C18H26N2O5, CAS 2382340-54-5](/s/GANFVPYUFFNOKQ-GJZGRUSLSA-N.svg)
tert-Butyl (3S,4S)-4-{[(benzyloxy)carbonyl]amino}-3-hydroxypiperidine-1-carboxylate
CAS 2382340-54-5C18H26N2O5
- cis-N-Cbz-3-methoxypiperidin-4-amine Hydrochloride1171128-40-7C14H21ClN2O3
- N-Cbz-1,4-dimethylpiperidin-4-amine1927863-19-1C15H22N2O2
- 1 supplierstert-Butyl cis-3-amino-4-(benzyloxycarbonylamino)piperidine-1-carboxylate766556-80-3C18H27N3O4
- cis-tert-Butyl 4-(benzyloxycarbonylamino)-3-methoxypiperidine-1-carboxylateC19H28N2O5
- Benzyl N-[(3R,4S)-3-fluoropiperidin-4-yl]carbamate577691-64-6C13H17FN2O2
- Benzyl N-[4-(hydroxymethyl)piperidin-4-yl]carbamate1067915-35-8C14H20N2O3
- Carbamic acid, N-[(3S,4S)-3-fluoro-4-piperidinyl]-, phenylmethyl ester1434127-00-0C13H17FN2O2
- Rel-benzyl ((3R,4R)-3-fluoropiperidin-4-yl)carbamate577691-96-4C13H17FN2O2
- 4-Benzyloxycarbonylamino-1-t-butyloxycarbonyl-3,3-dimethylpiperidine473838-64-1C20H30N2O4
- tert-Butyl (3R,4S)-3-amino-4-{[(benzyloxy)carbonyl]amino}piperidine-1-carboxylate1707290-21-8C18H27N3O4
- Benzyl ((3S,4S)-3-hydroxypiperidin-4-yl)carbamate1638743-89-1C13H18N2O3
- rac-(3R,4S)-4-{[(Benzyloxy)carbonyl]amino}-1-[(tert-butoxy)carbonyl]piperidine-3-carboxylic acid1552320-38-3C19H26N2O6
- Methyl (2S,4S)-4-(benzyloxycarbonylamino)piperidine-2-carboxylate1255664-48-2C15H20N2O4
- tert-Butyl 4-{[(benzyloxy)carbonyl]amino}-3-(hydroxymethyl)piperidine-1-carboxylate2680901-00-0C19H28N2O5
- Benzyl N-[1-(2-fluoropentyl)piperidin-4-yl]carbamate1427058-43-2C18H27FN2O2
- Benzyl piperidin-4-yl(trifluoromethyl)carbamate1420963-53-6C14H17F3N2O2
- Benzyl (1-(trifluoromethyl)piperidin-4-yl)carbamate1420900-36-2C14H17F3N2O2
- tert-Butyl 4-(((benzyloxy)carbonyl)amino)-4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate1447606-52-1C21H30N2O6
- Benzyl (1-(5-aminopent-2-yn-1-yl)piperidin-4-yl)carbamate dihydrochloride1416440-49-7C18H27Cl2N3O2
- Butyl 4-(((benzyloxy)carbonyl)amino)-4-methylpiperidine-1-carboxylate1060803-30-6C19H28N2O4
- Ethyl 4-{[(benzyloxy)carbonyl]amino}-4-cyanopiperidine-1-carboxylate1392491-64-3C17H21N3O4
- Benzyl (1-isopropylpiperidin-4-yl)carbamate609804-23-1C16H24N2O2
- tert-Butyl cis(+/-)-4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidine-1-carboxylate1171125-49-7C19H28N2O5
- tert-Butyl 4-((((3,5-dichlorobenzyl)oxy)carbonyl)amino)piperidine-1-carboxylate1613513-91-9C18H24Cl2N2O4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals