Murcko scaffold
Ring system with 6 rings and 21 atoms
9 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 21
- Chemicals
- 9
- With full pages
- 3
Scaffold SMILES
O=C1Nc2ccccc2C12C1CC3C(CO1)C1NCC3C12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 9 of 9 chemicals
Gelsemine, 1-methoxy-
C21H24N2O3
Gelsemine
CAS 509-15-9C20H22N2O2
Gelsevirine
C21H24N2O3
Gelsevirine
CAS 38990-03-3C21H24N2O3
Gelsemine hydrochloride
CAS 35306-33-3C20H23ClN2O2
![(1R,7S,8R)-2-Ethenyl-1'-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2'-one chemical structure, C21H24N2O3](/s/SSSCMFCWHWCCEH-VYKRIWGLSA-N.svg)
(1R,7S,8R)-2-Ethenyl-1'-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2'-one
C21H24N2O3
![(1R,2S,5S,6R,7S,8R,11S)-2-Ethenyl-1'-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2'-one chemical structure, C21H24N2O3](/s/SSSCMFCWHWCCEH-GLTYNWHWSA-N.svg)
(1R,2S,5S,6R,7S,8R,11S)-2-Ethenyl-1'-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2'-one
C21H24N2O3
1-Methoxygelsemine
C21H24N2O3
1-Methoxy-gelsemine
C21H24N2O3