Murcko scaffold

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)benzamide scaffold

81 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 21
Chemicals: 81
With full pages: 3

Scaffold SMILES

O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)benzamide page

Murcko scaffold O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 81 of 81 chemicals

$2-Bromo-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide hydrochloride chemical structure, C21H23BrClN3O3S, CAS 1216743-46-2$

2-Bromo-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide hydrochloride

CAS 1216743-46-2C₂₁H₂₃BrClN₃O₃S

$Methyl 2-[(11Z)-11-[(3-nitrobenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate chemical structure, C18H13N3O7S, CAS 905661-08-7$

Methyl 2-[(11Z)-11-[(3-nitrobenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate

CAS 905661-08-7C₁₈H₁₃N₃O₇S

(Z)-4-Acetyl-N-(7-allyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-ylidene)benzamide

CAS 905661-44-1C₂₀H₁₆N₂O₄S

$N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3,4,5-triethoxybenzamide chemical structure, C21H22N2O6S, CAS 892852-22-1$

N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3,4,5-triethoxybenzamide

CAS 892852-22-1C₂₁H₂₂N₂O₆S

(E)-Methyl 2-(6-((2,5-dimethoxybenzoyl)imino)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-7(6H)-yl)acetate

CAS 955814-44-5C₂₀H₁₈N₂O₇S

$N-[2-(Dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-nitrobenzamide hydrochloride chemical structure, C19H19ClN4O5S, CAS 1219201-94-1$

N-[2-(Dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-nitrobenzamide hydrochloride

CAS 1219201-94-1C₁₉H₁₉ClN₄O₅S

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-4-cyano-N-(2-(dimethylamino)ethyl)benzamide hydrochloride

CAS 1216638-87-7C₂₀H₁₉ClN₄O₃S

$4-Bromo-N-[3-(dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide hydrochloride chemical structure, C20H21BrClN3O3S, CAS 1215628-64-0$

4-Bromo-N-[3-(dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide hydrochloride

CAS 1215628-64-0C₂₀H₂₁BrClN₃O₃S

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-4-cyano-N-(3-(dimethylamino)propyl)benzamide hydrochloride

CAS 1215645-45-6C₂₁H₂₁ClN₄O₃S

$N-[3-(Dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-(trifluoromethyl)benzamide hydrochloride chemical structure, C21H21ClF3N3O3S, CAS 1216470-83-5$

N-[3-(Dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-(trifluoromethyl)benzamide hydrochloride

CAS 1216470-83-5C₂₁H₂₁ClF₃N₃O₃S

$4-(Diethylsulfamoyl)-N-[(11Z)-12-(prop-2-en-1-yl)-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-11-ylidene]benzamide chemical structure, C22H23N3O5S2, CAS 895451-66-8$

4-(Diethylsulfamoyl)-N-[(11Z)-12-(prop-2-en-1-yl)-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-11-ylidene]benzamide

CAS 895451-66-8C₂₂H₂₃N₃O₅S₂

$N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-(propane-2-sulfonyl)benzamide chemical structure, C18H16N2O5S2, CAS 941993-11-9$

N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-3-(propane-2-sulfonyl)benzamide

CAS 941993-11-9C₁₈H₁₆N₂O₅S₂

$4-(Diethylsulfamoyl)-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide chemical structure, C19H19N3O5S2, CAS 892853-92-8$

4-(Diethylsulfamoyl)-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide

CAS 892853-92-8C₁₉H₁₉N₃O₅S₂

$Methyl 2-[(11Z)-11-[(4-methylbenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate chemical structure, C19H16N2O5S, CAS 895450-47-2$

Methyl 2-[(11Z)-11-[(4-methylbenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate

CAS 895450-47-2C₁₉H₁₆N₂O₅S

$Methyl 2-[(11Z)-11-[(2-methoxybenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate chemical structure, C19H16N2O6S, CAS 895429-80-8$

Methyl 2-[(11Z)-11-[(2-methoxybenzoyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate

CAS 895429-80-8C₁₉H₁₆N₂O₆S

(Z)-N-(7-Allyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-ylidene)-2-methylbenzamide

CAS 1006797-36-9C₁₉H₁₆N₂O₃S

(Z)-Ethyl 2-(6-((2-nitrobenzoyl)imino)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-7(6H)-yl)acetate

CAS 895429-34-2C₁₉H₁₅N₃O₇S

(Z)-Ethyl 2-(6-((2,6-difluorobenzoyl)imino)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-7(6H)-yl)acetate

CAS 895430-44-1C₁₉H₁₄F₂N₂O₅S

(Z)-Ethyl 2-(6-((2,3-dimethoxybenzoyl)imino)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-7(6H)-yl)acetate

CAS 895434-29-4C₂₁H₂₀N₂O₇S

(Z)-N-(7-(2-(Methylthio)ethyl)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-ylidene)benzamide

CAS 1007063-38-8C₁₈H₁₆N₂O₃S₂

(Z)-2,4-Dimethyl-N-(7-propyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-ylidene)benzamide

CAS 1006974-24-8C₂₀H₂₀N₂O₃S

$N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-4-(dipropylsulfamoyl)benzamide chemical structure, C21H23N3O5S2, CAS 892856-20-1$

N-{4,6-Dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-4-(dipropylsulfamoyl)benzamide

CAS 892856-20-1C₂₁H₂₃N₃O₅S₂

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-4-(N,N-diallylsulfamoyl)benzamide

CAS 892843-89-9C₂₁H₁₉N₃O₅S₂

$4-[Butyl(methyl)sulfamoyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide chemical structure, C20H21N3O5S2, CAS 892852-59-4$

4-[Butyl(methyl)sulfamoyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}benzamide

CAS 892852-59-4C₂₀H₂₁N₃O₅S₂

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)benzamide scaffold

Chemicals with this scaffold

Related scaffolds