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Murcko scaffold

3-Phenylpiperidin-2-one scaffold

50 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
50
With full pages
4
Scaffold SMILES

O=C1NCCCC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpiperidin-2-one page
Murcko scaffold O=C1NCCCC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

1-(Ethoxycarbonyl)-3-hydroxy-3-phenyl-2-piperidinone chemical structure, C14H17NO4, CAS 65379-07-9
1-(Ethoxycarbonyl)-3-hydroxy-3-phenyl-2-piperidinone
CAS 65379-07-9C14H17NO4
3-Hydroxy-1-methyl-3-phenyl-2-piperidinone chemical structure, C12H15NO2, CAS 87532-76-1
3-Hydroxy-1-methyl-3-phenyl-2-piperidinone
CAS 87532-76-1C12H15NO2
3-Methoxy-3-phenyl-2-piperidinone chemical structure, C12H15NO2, CAS 87532-77-2
3-Methoxy-3-phenyl-2-piperidinone
CAS 87532-77-2C12H15NO2
1-(Ethoxycarbonyl)-3-methoxy-3-phenyl-2-piperidinone chemical structure, C15H19NO4, CAS 87532-78-3
1-(Ethoxycarbonyl)-3-methoxy-3-phenyl-2-piperidinone
CAS 87532-78-3C15H19NO4
Ethyl 2-oxo-3-phenylpiperidine-3-carboxylate chemical structure, C14H17NO3, CAS 63378-71-2
Ethyl 2-oxo-3-phenylpiperidine-3-carboxylate
CAS 63378-71-2C14H17NO3
2-Oxo-3-phenylpiperidine-3-carboxylic acid chemical structure, C12H13NO3, CAS 1026960-99-5
2-Oxo-3-phenylpiperidine-3-carboxylic acid
CAS 1026960-99-5C12H13NO3
3-Phenylpiperidin-2-one chemical structure, C11H13NO, CAS 51551-56-5
3-Phenylpiperidin-2-one
CAS 51551-56-5C11H13NO
3-Hydroxy-3-phenylpiperidin-2-one chemical structure, C11H13NO2, CAS 65379-06-8
3-Hydroxy-3-phenylpiperidin-2-one
CAS 65379-06-8C11H13NO2
Ethyl 2-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C14H17NO3, CAS 68475-10-5
Ethyl 2-oxo-3-phenylpiperidine-1-carboxylate
CAS 68475-10-5C14H17NO3
Ethyl 3-chloro-2-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C14H16ClNO3, CAS 68475-11-6
Ethyl 3-chloro-2-oxo-3-phenylpiperidine-1-carboxylate
CAS 68475-11-6C14H16ClNO3
Ethyl 3-amino-2-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C14H18N2O3, CAS 68475-16-1
Ethyl 3-amino-2-oxo-3-phenylpiperidine-1-carboxylate
CAS 68475-16-1C14H18N2O3
3-(3-Hydroxyphenyl)piperidin-2-one chemical structure, C11H13NO2, CAS 1893051-34-7
3-(3-Hydroxyphenyl)piperidin-2-one
CAS 1893051-34-7C11H13NO2
3-(3-Methoxyphenyl)piperidin-2-one chemical structure, C12H15NO2, CAS 1267270-37-0
3-(3-Methoxyphenyl)piperidin-2-one
CAS 1267270-37-0C12H15NO2
3-(3-Methylphenyl)piperidin-2-one chemical structure, C12H15NO, CAS 1267455-56-0
3-(3-Methylphenyl)piperidin-2-one
CAS 1267455-56-0C12H15NO
Ethyl 3-(acetyloxy)-2-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C16H19NO5, CAS 87532-83-0
Ethyl 3-(acetyloxy)-2-oxo-3-phenylpiperidine-1-carboxylate
CAS 87532-83-0C16H19NO5
2-Oxo-3-phenylpiperidin-3-yl bromoacetate chemical structure, C13H14BrNO3, CAS 87532-81-8
2-Oxo-3-phenylpiperidin-3-yl bromoacetate
CAS 87532-81-8C13H14BrNO3
1-(Chloroacetyl)-3-hydroxy-3-phenylpiperidin-2-one chemical structure, C13H14ClNO3, CAS 87532-79-4
1-(Chloroacetyl)-3-hydroxy-3-phenylpiperidin-2-one
CAS 87532-79-4C13H14ClNO3
2-Piperidone, 3-amino-1-methyl-3-phenyl- chemical structure, C12H16N2O, CAS 801151-81-5
2-Piperidone, 3-amino-1-methyl-3-phenyl-
CAS 801151-81-5C12H16N2O
3-(4-Bromophenyl)piperidin-2-one chemical structure, C11H12BrNO, CAS 769944-71-0
3-(4-Bromophenyl)piperidin-2-one
CAS 769944-71-0C11H12BrNO
4-(2-Oxopiperidin-3-yl)benzoic acid chemical structure, C12H13NO3, CAS 936636-70-3
4-(2-Oxopiperidin-3-yl)benzoic acid
CAS 936636-70-3C12H13NO3
1-Amino-3-(2-chlorophenyl)-2-piperidinone chemical structure, C11H13ClN2O, CAS 1123193-79-2
1-Amino-3-(2-chlorophenyl)-2-piperidinone
CAS 1123193-79-2C11H13ClN2O
1-Amino-3-(3,4,5-trifluorophenyl)piperidin-2-one chemical structure, C11H11F3N2O, CAS 949560-37-6
1-Amino-3-(3,4,5-trifluorophenyl)piperidin-2-one
CAS 949560-37-6C11H11F3N2O
1-Amino-3-(4-fluoro-3-methylphenyl)-2-piperidinone chemical structure, C12H15FN2O, CAS 1123196-47-3
1-Amino-3-(4-fluoro-3-methylphenyl)-2-piperidinone
CAS 1123196-47-3C12H15FN2O
3-[3-(Trifluoromethyl)phenyl]piperidin-2-one chemical structure, C12H12F3NO, CAS 1891169-96-2
3-[3-(Trifluoromethyl)phenyl]piperidin-2-one
CAS 1891169-96-2C12H12F3NO