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Murcko scaffold

Ring system with 4 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
5
Scaffold SMILES

O=c1oc2cccc(OCc3ccccc3)c2c2c1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2cccc(OCc3ccccc3)c2c2c1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

7-Methyl-9-((4-vinylbenzyl)oxy)-2,3-dihydrocyclopenta(C)chromen-4(1H)-one chemical structure, C22H20O3, CAS 314744-37-1
7-Methyl-9-((4-vinylbenzyl)oxy)-2,3-dihydrocyclopenta(C)chromen-4(1H)-one
CAS 314744-37-1C22H20O3
9-(Benzyloxy)-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H18O3, CAS 307549-60-6
9-(Benzyloxy)-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 307549-60-6C20H18O3
9-[(2-Methoxybenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C21H20O4, CAS 374768-04-4
9-[(2-Methoxybenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374768-04-4C21H20O4
RefChem:388667 chemical structure, C21H17F3O3, CAS 6625-80-5
RefChem:388667
CAS 6625-80-5C21H17F3O3
7-Methyl-9-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C23H24O6, CAS 376383-90-3
7-Methyl-9-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 376383-90-3C23H24O6
4-(((7-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy)methyl)benzoic acid chemical structure, C21H18O5, CAS 314744-39-3
4-(((7-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy)methyl)benzoic acid
CAS 314744-39-3C21H18O5
9-[(3-Methoxybenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C21H20O4, CAS 374766-44-6
9-[(3-Methoxybenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374766-44-6C21H20O4
7-Methyl-9-[(pentafluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H13F5O3, CAS 380322-55-4
7-Methyl-9-[(pentafluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 380322-55-4C20H13F5O3
9-[(4-Fluorophenyl)methoxy]-7-methyl-2,3-dihydro-1H-cyclopenta[c]chromen-4-one chemical structure, C20H17FO3, CAS 307549-63-9
9-[(4-Fluorophenyl)methoxy]-7-methyl-2,3-dihydro-1H-cyclopenta[c]chromen-4-one
CAS 307549-63-9C20H17FO3
9-[(2-Chlorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H17ClO3, CAS 307549-64-0
9-[(2-Chlorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 307549-64-0C20H17ClO3
9-[(2-Chloro-6-fluorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H16ClFO3, CAS 314744-36-0
9-[(2-Chloro-6-fluorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 314744-36-0C20H16ClFO3
[(7-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy](phenyl)acetic acid chemical structure, C21H18O5, CAS 500204-21-7
[(7-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy](phenyl)acetic acid
CAS 500204-21-7C21H18O5
Methyl 4-{[(7-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy]methyl}benzoate chemical structure, C22H20O5, CAS 314744-38-2
Methyl 4-{[(7-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy]methyl}benzoate
CAS 314744-38-2C22H20O5
9-[(2-Fluorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H17FO3, CAS 314744-34-8
9-[(2-Fluorobenzyl)oxy]-7-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 314744-34-8C20H17FO3