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Murcko scaffold

Ring system with 3 rings and 17 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
12
With full pages
5
Scaffold SMILES

O=c1ccccc2cn(-c3ccccc3)cc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccccc2cn(-c3ccccc3)cc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

8-Ethoxy-2-(4-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C20H21NO3, CAS 329726-63-8
8-Ethoxy-2-(4-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 329726-63-8C20H21NO3
RefChem:388652 chemical structure, C20H21NO2, CAS 5652-36-8
RefChem:388652
CAS 5652-36-8C20H21NO2
2-(3,5-Dimethylphenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C20H21NO2, CAS 461436-54-4
2-(3,5-Dimethylphenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461436-54-4C20H21NO2
8-Methoxy-1,3-dimethyl-2-(3-nitrophenyl)cyclohepta[c]pyrrol-4(2H)-one chemical structure, C18H16N2O4, CAS 461431-29-8
8-Methoxy-1,3-dimethyl-2-(3-nitrophenyl)cyclohepta[c]pyrrol-4(2H)-one
CAS 461431-29-8C18H16N2O4
8-Methoxy-2-(3-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C19H19NO3, CAS 461439-00-9
8-Methoxy-2-(3-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461439-00-9C19H19NO3
8-Methoxy-2-(2-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C19H19NO3, CAS 461431-30-1
8-Methoxy-2-(2-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461431-30-1C19H19NO3
8-Methoxy-2-(4-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C19H19NO3, CAS 461439-04-3
8-Methoxy-2-(4-methoxyphenyl)-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461439-04-3C19H19NO3
2-(4-Ethoxyphenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C20H21NO3, CAS 461432-20-2
2-(4-Ethoxyphenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461432-20-2C20H21NO3
4-(4-Ethoxy-1,3-dimethyl-8-oxocyclohepta[c]pyrrol-2-yl)benzoic acid chemical structure, C20H19NO4, CAS 780779-13-7
4-(4-Ethoxy-1,3-dimethyl-8-oxocyclohepta[c]pyrrol-2-yl)benzoic acid
CAS 780779-13-7C20H19NO4
2-(4-Iodophenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C18H16INO2, CAS 461437-08-1
2-(4-Iodophenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461437-08-1C18H16INO2
2-(4-Bromophenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one chemical structure, C18H16BrNO2, CAS 461437-78-5
2-(4-Bromophenyl)-8-methoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one
CAS 461437-78-5C18H16BrNO2
2-(4-Bromophenyl)-4-ethoxy-1,3-dimethylcyclohepta[c]pyrrol-8-one chemical structure, C19H18BrNO2, CAS 461432-18-8
2-(4-Bromophenyl)-4-ethoxy-1,3-dimethylcyclohepta[c]pyrrol-8-one
CAS 461432-18-8C19H18BrNO2