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Murcko scaffold

Ring system with 2 rings and 12 atoms

60 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
60
With full pages
9
Scaffold SMILES

c1cncc(OCC2CCN2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cncc(OCC2CCN2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

5-(123I)Iodo-3-(2(S)-azetidinylmethoxy)pyridine chemical structure, C9H11IN2O, CAS 207565-03-5
5-(123I)Iodo-3-(2(S)-azetidinylmethoxy)pyridine
CAS 207565-03-5C9H11IN2O
2-Fluoro-3-(2S-azetidinylmethoxy)pyridine, F-18 chemical structure, C9H11FN2O, CAS 205594-65-6
2-Fluoro-3-(2S-azetidinylmethoxy)pyridine, F-18
CAS 205594-65-6C9H11FN2O
Tebanicline chemical structure, C9H11ClN2O, CAS 198283-73-7
Tebanicline
CAS 198283-73-7C9H11ClN2O
3-((2S)-Azetidin-2-ylmethoxy)pyridine chemical structure, C9H12N2O, CAS 161416-98-4
3-((2S)-Azetidin-2-ylmethoxy)pyridine
CAS 161416-98-4C9H12N2O
3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine chemical structure, C9H11IN2O, CAS 213550-82-4
3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine
CAS 213550-82-4C9H11IN2O
Tebanicline tosylate chemical structure, C16H19ClN2O4S, CAS 198283-74-8
Tebanicline tosylate
CAS 198283-74-8C16H19ClN2O4S
Txg75jse9G chemical structure, C10H14N2O, CAS 209326-28-3
Txg75jse9G
CAS 209326-28-3C10H14N2O
2-Fluoro-A-85380 chemical structure, C9H11FN2O, CAS 186588-98-7
2-Fluoro-A-85380
CAS 186588-98-7C9H11FN2O
(S)-3-(Azetidin-2-ylmethoxy)pyridine dihydrochloride chemical structure, C9H14Cl2N2O, CAS 174740-86-4
(S)-3-(Azetidin-2-ylmethoxy)pyridine dihydrochloride
CAS 174740-86-4C9H14Cl2N2O
5-Iodo-A-85380, 5-trimethylstannyl N-boc derivative chemical structure, C17H28N2O3Sn, CAS 213766-21-3
5-Iodo-A-85380, 5-trimethylstannyl N-boc derivative
CAS 213766-21-3C17H28N2O3Sn
3-[[(2S)-1-Methyl-2-azetidinyl]methoxy]pyridine chemical structure, C10H14N2O, CAS 161416-99-5
3-[[(2S)-1-Methyl-2-azetidinyl]methoxy]pyridine
CAS 161416-99-5C10H14N2O
1,1-Dimethylethyl (2S)-2-[[[2-(dimethylamino)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylate chemical structure, C16H25N3O3, CAS 233766-73-9
1,1-Dimethylethyl (2S)-2-[[[2-(dimethylamino)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylate
CAS 233766-73-9C16H25N3O3
N-Boc-2-trimethylammonium-A 85380 Triflate chemical structure, C18H28F3N3O6S, CAS 233766-75-1
N-Boc-2-trimethylammonium-A 85380 Triflate
CAS 233766-75-1C18H28F3N3O6S
1-Azetidinecarboxylic acid, 2-[[[2-nitro-3-pyridinyl]oxy]methyl]-, 1,1-dimethylethyl ester, (2S)- chemical structure, C14H19N3O5, CAS 209530-92-7
1-Azetidinecarboxylic acid, 2-[[[2-nitro-3-pyridinyl]oxy]methyl]-, 1,1-dimethylethyl ester, (2S)-
CAS 209530-92-7C14H19N3O5
(S)-tert-Butyl 2-(((5-bromopyridin-3-yl)oxy)methyl)azetidine-1-carboxylate chemical structure, C14H19BrN2O3, CAS 186593-31-7
(S)-tert-Butyl 2-(((5-bromopyridin-3-yl)oxy)methyl)azetidine-1-carboxylate
CAS 186593-31-7C14H19BrN2O3
2-Chloro-5-{[(2S)-1-methylazetidin-2-yl]methoxy}pyridine chemical structure, C10H13ClN2O, CAS 203564-55-0
2-Chloro-5-{[(2S)-1-methylazetidin-2-yl]methoxy}pyridine
CAS 203564-55-0C10H13ClN2O
1,1-Dimethylethyl (2S)-2-[[(6-nitro-3-pyridinyl)oxy]methyl]-1-azetidinecarboxylate chemical structure, C14H19N3O5, CAS 280141-83-5
1,1-Dimethylethyl (2S)-2-[[(6-nitro-3-pyridinyl)oxy]methyl]-1-azetidinecarboxylate
CAS 280141-83-5C14H19N3O5
6-(5-(((S)-Azetidin-2-yl)methoxy)pyridine-3-yl)hex-5-yn-1-ol chemical structure, C15H20N2O2, CAS 820231-95-6
6-(5-(((S)-Azetidin-2-yl)methoxy)pyridine-3-yl)hex-5-yn-1-ol
CAS 820231-95-6C15H20N2O2
47QA4Ttq7Y chemical structure, C10H14N2O, CAS 458569-35-2
47QA4Ttq7Y
CAS 458569-35-2C10H14N2O
Pyridine, 3-(2-azetidinylmethoxy)-, hydrochloride (1:2) chemical structure, C9H14Cl2N2O, CAS 1706428-66-1
Pyridine, 3-(2-azetidinylmethoxy)-, hydrochloride (1:2)
CAS 1706428-66-1C9H14Cl2N2O
(S)-3-(Azetidin-2-ylmethoxy)-2-methylpyridine chemical structure, C10H14N2O, CAS 161417-13-6
(S)-3-(Azetidin-2-ylmethoxy)-2-methylpyridine
CAS 161417-13-6C10H14N2O
tert-Butyl 2-(((5-bromopyridin-3-yl)oxy)methyl)azetidine-1-carboxylate chemical structure, C14H19BrN2O3, CAS 1823500-18-0
tert-Butyl 2-(((5-bromopyridin-3-yl)oxy)methyl)azetidine-1-carboxylate
CAS 1823500-18-0C14H19BrN2O3
tert-Butyl 2-(((5-allylpyridin-3-yl)oxy)methyl)azetidine-1-carboxylate chemical structure, C17H24N2O3, CAS 1311254-61-1
tert-Butyl 2-(((5-allylpyridin-3-yl)oxy)methyl)azetidine-1-carboxylate
CAS 1311254-61-1C17H24N2O3
2-Chloro-3-(1-Boc-2-(R)-azetidinylmethoxy)pyridine chemical structure, C14H19ClN2O3, CAS 209328-75-6
2-Chloro-3-(1-Boc-2-(R)-azetidinylmethoxy)pyridine
CAS 209328-75-6C14H19ClN2O3