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Murcko scaffold

2-Cyclobutyl-1-phenylethan-1-one scaffold

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
12
With full pages
2
Scaffold SMILES

O=C(CC1CCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclobutyl-1-phenylethan-1-one page
Murcko scaffold O=C(CC1CCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Acetophenone, alpha-(1-chloro-2,2,3,3,4,4-hexafluorocyclobutyl)- chemical structure, C12H7ClF6O, CAS 97805-06-6
Acetophenone, alpha-(1-chloro-2,2,3,3,4,4-hexafluorocyclobutyl)-
CAS 97805-06-6C12H7ClF6O
2-Cyclobutyl-1-(4-fluorophenyl)ethan-1-one chemical structure, C12H13FO, CAS 1494879-19-4
2-Cyclobutyl-1-(4-fluorophenyl)ethan-1-one
CAS 1494879-19-4C12H13FO
Ethanone, 1-(4-chlorophenyl)-2-cyclobutyl- chemical structure, C12H13ClO, CAS 102580-67-6
Ethanone, 1-(4-chlorophenyl)-2-cyclobutyl-
CAS 102580-67-6C12H13ClO
4-[2-Cyano-2-(3,3-difluorocyclobutyl)acetyl]benzonitrile chemical structure, C14H10F2N2O, CAS 1219019-03-0
4-[2-Cyano-2-(3,3-difluorocyclobutyl)acetyl]benzonitrile
CAS 1219019-03-0C14H10F2N2O
1-(2-Aminophenyl)-2-cyclobutylethan-1-one chemical structure, C12H15NO, CAS 1492526-79-0
1-(2-Aminophenyl)-2-cyclobutylethan-1-one
CAS 1492526-79-0C12H15NO
2-Cyclobutyl-1-(3-fluorophenyl)ethan-1-one chemical structure, C12H13FO, CAS 1496165-61-7
2-Cyclobutyl-1-(3-fluorophenyl)ethan-1-one
CAS 1496165-61-7C12H13FO
2-Cyclobutyl-1-phenylethan-1-one chemical structure, C12H14O, CAS 140451-91-8
2-Cyclobutyl-1-phenylethan-1-one
CAS 140451-91-8C12H14O
2-Cyclobutyl-1-(2-fluorophenyl)ethan-1-one chemical structure, C12H13FO, CAS 1466479-86-6
2-Cyclobutyl-1-(2-fluorophenyl)ethan-1-one
CAS 1466479-86-6C12H13FO
1-(4-((tert-Butyldimethylsilyl)oxy)phenyl)-2-cyclobutylethan-1-one chemical structure, C18H28O2Si, CAS 2135331-91-6
1-(4-((tert-Butyldimethylsilyl)oxy)phenyl)-2-cyclobutylethan-1-one
CAS 2135331-91-6C18H28O2Si
2-Cyclobutyl-1-(4-hydroxyphenyl)ethan-1-one chemical structure, C12H14O2, CAS 2135332-94-2
2-Cyclobutyl-1-(4-hydroxyphenyl)ethan-1-one
CAS 2135332-94-2C12H14O2
tert-Butyl N-[2-(2-cyclobutylacetyl)phenyl]carbamate chemical structure, C17H23NO3, CAS 1999416-65-7
tert-Butyl N-[2-(2-cyclobutylacetyl)phenyl]carbamate
CAS 1999416-65-7C17H23NO3
2-(3,3-Difluorocyclobutyl)-1-phenylethan-1-one chemical structure, C12H12F2O, CAS 2301312-01-4
2-(3,3-Difluorocyclobutyl)-1-phenylethan-1-one
CAS 2301312-01-4C12H12F2O