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Murcko scaffold

5,6-Diphenyl-3-piperidin-1-yl-1,2,4-triazine scaffold

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
16
With full pages
1
Scaffold SMILES

c1ccc(-c2nnc(N3CCCCC3)nc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6-Diphenyl-3-piperidin-1-yl-1,2,4-triazine page
Murcko scaffold c1ccc(-c2nnc(N3CCCCC3)nc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

LY 81067 chemical structure, C22H24N4O, CAS 87186-60-5
LY 81067
CAS 87186-60-5C22H24N4O
5,6-Diphenyl-3-piperidin-1-yl-1,2,4-triazine chemical structure, C20H20N4, CAS 37398-95-1
5,6-Diphenyl-3-piperidin-1-yl-1,2,4-triazine
CAS 37398-95-1C20H20N4
1,2,4-Triazine, 5,6-bis(4-methoxyphenyl)-3-(1-piperidinyl)- chemical structure, C22H24N4O2, CAS 54866-73-8
1,2,4-Triazine, 5,6-bis(4-methoxyphenyl)-3-(1-piperidinyl)-
CAS 54866-73-8C22H24N4O2
{1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-yl}methanol chemical structure, C23H26N4O, CAS 88300-46-3
{1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-yl}methanol
CAS 88300-46-3C23H26N4O
1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidine-4-carboxamide chemical structure, C23H25N5O, CAS 88300-45-2
1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidine-4-carboxamide
CAS 88300-45-2C23H25N5O
1-(5,6-Bis(4-ethylphenyl)-1,2,4-triazin-3-yl)piperidin-4-ol chemical structure, C24H28N4O, CAS 88300-17-8
1-(5,6-Bis(4-ethylphenyl)-1,2,4-triazin-3-yl)piperidin-4-ol
CAS 88300-17-8C24H28N4O
1-[5,6-Bis(2-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol chemical structure, C22H24N4O, CAS 88300-18-9
1-[5,6-Bis(2-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol
CAS 88300-18-9C22H24N4O
1-[5,6-Bis(3-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol chemical structure, C22H24N4O, CAS 88300-19-0
1-[5,6-Bis(3-methylphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol
CAS 88300-19-0C22H24N4O
1-(5,6-Bis(4-chlorophenyl)-1,2,4-triazin-3-yl)piperidin-4-ol chemical structure, C20H18Cl2N4O, CAS 88300-20-3
1-(5,6-Bis(4-chlorophenyl)-1,2,4-triazin-3-yl)piperidin-4-ol
CAS 88300-20-3C20H18Cl2N4O
5,6-Bis(4-methylphenyl)-3-(piperidin-1-yl)-1,2,4-triazine chemical structure, C22H24N4, CAS 88300-29-2
5,6-Bis(4-methylphenyl)-3-(piperidin-1-yl)-1,2,4-triazine
CAS 88300-29-2C22H24N4
5,6-Bis(4-methylphenyl)-3-(4-methylpiperidin-1-yl)-1,2,4-triazine chemical structure, C23H26N4, CAS 88300-34-9
5,6-Bis(4-methylphenyl)-3-(4-methylpiperidin-1-yl)-1,2,4-triazine
CAS 88300-34-9C23H26N4
3-(4-Methoxypiperidin-1-yl)-5,6-bis(4-methylphenyl)-1,2,4-triazine chemical structure, C23H26N4O, CAS 88300-35-0
3-(4-Methoxypiperidin-1-yl)-5,6-bis(4-methylphenyl)-1,2,4-triazine
CAS 88300-35-0C23H26N4O
3-(4-Ethoxypiperidin-1-yl)-5,6-bis(4-methylphenyl)-1,2,4-triazine chemical structure, C24H28N4O, CAS 88300-36-1
3-(4-Ethoxypiperidin-1-yl)-5,6-bis(4-methylphenyl)-1,2,4-triazine
CAS 88300-36-1C24H28N4O
1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidin-3-ol chemical structure, C22H24N4O, CAS 88300-32-7
1-[5,6-Bis(4-methylphenyl)-1,2,4-triazin-3-yl]piperidin-3-ol
CAS 88300-32-7C22H24N4O
1-(5,6-Bis(4-(dimethylamino)phenyl)-1,2,4-triazin-3-yl)piperidin-4-ol chemical structure, C24H30N6O, CAS 59689-78-0
1-(5,6-Bis(4-(dimethylamino)phenyl)-1,2,4-triazin-3-yl)piperidin-4-ol
CAS 59689-78-0C24H30N6O
1-[5,6-Bis(4-methoxyphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol chemical structure, C22H24N4O3, CAS 59663-59-1
1-[5,6-Bis(4-methoxyphenyl)-1,2,4-triazin-3-yl]piperidin-4-ol
CAS 59663-59-1C22H24N4O3