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Murcko scaffold

N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide scaffold

39 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
39
With full pages
4
Scaffold SMILES

O=S(=O)(NCC(c1ccco1)N1CCN(c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide page
Murcko scaffold O=S(=O)(NCC(c1ccco1)N1CCN(c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

4-Fluoro-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide chemical structure, C22H23F2N3O3S, CAS 877648-28-7
4-Fluoro-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide
CAS 877648-28-7C22H23F2N3O3S
4-Fluoro-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzene-1-sulfonamide chemical structure, C22H23F2N3O3S, CAS 877648-48-1
4-Fluoro-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzene-1-sulfonamide
CAS 877648-48-1C22H23F2N3O3S
N-{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzenesulfonamide chemical structure, C22H24FN3O3S, CAS 877648-54-9
N-{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzenesulfonamide
CAS 877648-54-9C22H24FN3O3S
4-Fluoro-N-(2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C22H24FN3O3S, CAS 877648-11-8
4-Fluoro-N-(2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 877648-11-8C22H24FN3O3S
N-(2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethoxybenzenesulfonamide chemical structure, C24H29N3O5S, CAS 877648-09-4
N-(2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethoxybenzenesulfonamide
CAS 877648-09-4C24H29N3O5S
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2,4,6-trimethylbenzene-1-sulfonamide chemical structure, C25H31N3O3S, CAS 877648-15-2
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2,4,6-trimethylbenzene-1-sulfonamide
CAS 877648-15-2C25H31N3O3S
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C22H25N3O3S, CAS 877648-16-3
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 877648-16-3C22H25N3O3S
2,5-Difluoro-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide chemical structure, C22H22F3N3O3S, CAS 877648-27-6
2,5-Difluoro-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide
CAS 877648-27-6C22H22F3N3O3S
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxybenzenesulfonamide chemical structure, C23H26FN3O4S, CAS 877648-35-6
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxybenzenesulfonamide
CAS 877648-35-6C23H26FN3O4S
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C24H28FN3O4S, CAS 877648-38-9
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide
CAS 877648-38-9C24H28FN3O4S
N-{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-3,4-dimethoxybenzene-1-sulfonamide chemical structure, C24H28FN3O5S, CAS 877648-44-7
N-{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-3,4-dimethoxybenzene-1-sulfonamide
CAS 877648-44-7C24H28FN3O5S
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methylbenzenesulfonamide chemical structure, C23H26FN3O3S, CAS 877648-59-4
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methylbenzenesulfonamide
CAS 877648-59-4C23H26FN3O3S
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C24H28FN3O4S, CAS 877648-84-5
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide
CAS 877648-84-5C24H28FN3O4S
N-(2-(Furan-2-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-2,4,6-trimethylbenzenesulfonamide chemical structure, C26H33N3O4S, CAS 877648-99-2
N-(2-(Furan-2-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-2,4,6-trimethylbenzenesulfonamide
CAS 877648-99-2C26H33N3O4S
N-(2-(Furan-2-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C25H31N3O5S, CAS 877649-13-3
N-(2-(Furan-2-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide
CAS 877649-13-3C25H31N3O5S
4-Bromo-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C22H24BrN3O3S, CAS 877648-17-4
4-Bromo-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 877648-17-4C22H24BrN3O3S
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-4-methylbenzene-1-sulfonamide chemical structure, C23H27N3O3S, CAS 877648-18-5
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-4-methylbenzene-1-sulfonamide
CAS 877648-18-5C23H27N3O3S
4-Chloro-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzene-1-sulfonamide chemical structure, C22H24ClN3O3S, CAS 877648-19-6
4-Chloro-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]benzene-1-sulfonamide
CAS 877648-19-6C22H24ClN3O3S
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-4-methoxybenzene-1-sulfonamide chemical structure, C23H27N3O4S, CAS 877648-20-9
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-4-methoxybenzene-1-sulfonamide
CAS 877648-20-9C23H27N3O4S
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-3,4-dimethoxybenzene-1-sulfonamide chemical structure, C24H28FN3O5S, CAS 877648-26-5
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-3,4-dimethoxybenzene-1-sulfonamide
CAS 877648-26-5C24H28FN3O5S
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-2,4,6-trimethylbenzene-1-sulfonamide chemical structure, C25H30FN3O3S, CAS 877648-30-1
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-2,4,6-trimethylbenzene-1-sulfonamide
CAS 877648-30-1C25H30FN3O3S
4-Bromo-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide chemical structure, C22H23BrFN3O3S, CAS 877648-32-3
4-Bromo-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide
CAS 877648-32-3C22H23BrFN3O3S
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-4-methylbenzene-1-sulfonamide chemical structure, C23H26FN3O3S, CAS 877648-33-4
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}-4-methylbenzene-1-sulfonamide
CAS 877648-33-4C23H26FN3O3S
4-Chloro-N-{2-[4-(4-fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzene-1-sulfonamide chemical structure, C22H23ClFN3O3S, CAS 877648-34-5
4-Chloro-N-{2-[4-(4-fluorophenyl)piperazin-1-yl]-2-(furan-2-yl)ethyl}benzene-1-sulfonamide
CAS 877648-34-5C22H23ClFN3O3S