Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 2 rings and 12 atoms

41 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 12
Chemicals: 41
With full pages: 8

Scaffold SMILES

O=C1CC=NN1c1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1CC=NN1c1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

3-Methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H9N3O, CAS 29211-49-2

3-Methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one

CAS 29211-49-2C₉H₉N₃O

3-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H8F3N3O, CAS 132214-72-3

3-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-4,5-dihydro-1H-pyrazol-5-one

CAS 132214-72-3C₁₀H₈F₃N₃O

2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H9ClF3N3O2, CAS 338420-89-6

2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one

CAS 338420-89-6C₁₁H₉ClF₃N₃O₂

2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2,4-dihydro-3H-pyrazol-3-one chemical structure, C9H5ClF3N3O, CAS 320419-14-5

2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2,4-dihydro-3H-pyrazol-3-one

CAS 320419-14-5C₉H₅ClF₃N₃O

5-Methyl-2-(5-nitro-2-pyridinyl)-4H-pyrazol-3-one chemical structure, C9H8N4O3, CAS 77556-53-7

5-Methyl-2-(5-nitro-2-pyridinyl)-4H-pyrazol-3-one

CAS 77556-53-7C₉H₈N₄O₃

3,4-Dimethyl-1-(pyridin-2-yl)-1H-pyrazol-5(4H)-one chemical structure, C10H11N3O, CAS 90840-09-8

3,4-Dimethyl-1-(pyridin-2-yl)-1H-pyrazol-5(4H)-one

CAS 90840-09-8C₁₀H₁₁N₃O

2,4-Dihydro-2-(2-pyridyl)-5-propyl-3H-pyrazol-3-one chemical structure, C11H13N3O, CAS 111987-95-2

2,4-Dihydro-2-(2-pyridyl)-5-propyl-3H-pyrazol-3-one

CAS 111987-95-2C₁₁H₁₃N₃O

1-(5-Chloropyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H8ClN3O, CAS 111988-00-2

1-(5-Chloropyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one

CAS 111988-00-2C₉H₈ClN₃O

2-{1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-5-oxo-4,5-dihydro-1H-pyrazol-3-yl}acetic acid chemical structure, C11H7ClF3N3O3, CAS 1097785-66-4

2-{1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-5-oxo-4,5-dihydro-1H-pyrazol-3-yl}acetic acid

CAS 1097785-66-4C₁₁H₇ClF₃N₃O₃

1-(5-Aminopyridin-2-yl)-3-propyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C11H14N4O, CAS 1184388-52-0

1-(5-Aminopyridin-2-yl)-3-propyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1184388-52-0C₁₁H₁₄N₄O

1-(5-Aminopyridin-2-yl)-3-(tert-butyl)-1H-pyrazol-5(4H)-one chemical structure, C12H16N4O, CAS 1184745-38-7

1-(5-Aminopyridin-2-yl)-3-(tert-butyl)-1H-pyrazol-5(4H)-one

CAS 1184745-38-7C₁₂H₁₆N₄O

1-(5-Aminopyridin-2-yl)-3-ethyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H12N4O, CAS 1178187-90-0

1-(5-Aminopyridin-2-yl)-3-ethyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1178187-90-0C₁₀H₁₂N₄O

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H10N4O, CAS 1179685-42-7

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1179685-42-7C₉H₁₀N₄O

1-(5-Aminopyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one chemical structure, C9H7F3N4O, CAS 1182794-13-3

1-(5-Aminopyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one

CAS 1182794-13-3C₉H₇F₃N₄O

1-(5-Aminopyridin-2-yl)-3-(propan-2-yl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C11H14N4O, CAS 1178664-26-0

1-(5-Aminopyridin-2-yl)-3-(propan-2-yl)-4,5-dihydro-1H-pyrazol-5-one

CAS 1178664-26-0C₁₁H₁₄N₄O

1-(5-Aminopyridin-2-yl)-3,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H12N4O, CAS 1182776-29-9

1-(5-Aminopyridin-2-yl)-3,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1182776-29-9C₁₀H₁₂N₄O

1-(5-Aminopyridin-2-yl)-4-ethyl-3-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C11H14N4O, CAS 1182758-00-4

1-(5-Aminopyridin-2-yl)-4-ethyl-3-methyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1182758-00-4C₁₁H₁₄N₄O

1-(5-Aminopyridin-2-yl)-3-(methoxymethyl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H12N4O2, CAS 1249072-71-6

1-(5-Aminopyridin-2-yl)-3-(methoxymethyl)-4,5-dihydro-1H-pyrazol-5-one

CAS 1249072-71-6C₁₀H₁₂N₄O₂

1-(5-Aminopyridin-2-yl)-3-(difluoromethyl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H8F2N4O, CAS 1340218-96-3

1-(5-Aminopyridin-2-yl)-3-(difluoromethyl)-4,5-dihydro-1H-pyrazol-5-one

CAS 1340218-96-3C₉H₈F₂N₄O

2-(5-Aminopyridin-2-yl)-4-isopropyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C12H16N4O, CAS 1407441-16-0

2-(5-Aminopyridin-2-yl)-4-isopropyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one

CAS 1407441-16-0C₁₂H₁₆N₄O

1-(5-Bromopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H8BrN3O, CAS 1487824-34-9

1-(5-Bromopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one

CAS 1487824-34-9C₉H₈BrN₃O

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one dihydrochloride chemical structure, C9H12Cl2N4O, CAS 2649014-49-1

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one dihydrochloride

CAS 2649014-49-1C₉H₁₂Cl₂N₄O

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one hydrochloride chemical structure, C9H11ClN4O, CAS 2648972-24-9

1-(5-Aminopyridin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one hydrochloride

CAS 2648972-24-9C₉H₁₁ClN₄O

3-Ethyl-1-(5-nitropyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H10N4O3, CAS 2649069-79-2

3-Ethyl-1-(5-nitropyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one

CAS 2649069-79-2C₁₀H₁₀N₄O₃