CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 12 atoms

42 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
12
Chemicals
42
With full pages
4
Scaffold SMILES

c1ccc(C2OC3CC2C3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2OC3CC2C3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Ethyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo(2.1.1)hexane-4-carboxylate chemical structure, C15H19NO3, CAS 2228470-51-5
Ethyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo(2.1.1)hexane-4-carboxylate
CAS 2228470-51-5C15H19NO3
[(1s)-3-Phenyl-2-oxabicyclo[2.1.1]hexan-1-yl]methanol chemical structure, C12H14O2, CAS 2731009-67-7
[(1s)-3-Phenyl-2-oxabicyclo[2.1.1]hexan-1-yl]methanol
CAS 2731009-67-7C12H14O2
1-[(1s)-3-Phenyl-2-oxabicyclo[2.1.1]hexan-1-yl]methanamine chemical structure, C12H15NO, CAS 2731009-22-4
1-[(1s)-3-Phenyl-2-oxabicyclo[2.1.1]hexan-1-yl]methanamine
CAS 2731009-22-4C12H15NO
3-Phenyl-2-oxabicyclo(2.1.1)hexane-1-carboxylic acid chemical structure, C12H12O3, CAS 2731009-06-4
3-Phenyl-2-oxabicyclo(2.1.1)hexane-1-carboxylic acid
CAS 2731009-06-4C12H12O3
Ethyl3-(3,4-dichlorophenyl)-1-methyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C15H16Cl2O3, CAS 2758001-60-2
Ethyl3-(3,4-dichlorophenyl)-1-methyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2758001-60-2C15H16Cl2O3
3-(3,4-Dichlorophenyl)-1-methyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C13H12Cl2O3, CAS 2758005-52-4
3-(3,4-Dichlorophenyl)-1-methyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2758005-52-4C13H12Cl2O3
Ethyl 3-(3,4-dichlorophenyl)-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C15H15Cl2IO3, CAS 2758002-01-4
Ethyl 3-(3,4-dichlorophenyl)-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2758002-01-4C15H15Cl2IO3
(1s)-1-(Iodomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane chemical structure, C12H13IO, CAS 2825011-31-0
(1s)-1-(Iodomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane
CAS 2825011-31-0C12H13IO
Ethyl 1-(iodomethyl)-3-{3-[(trifluoromethyl)sulfanyl]phenyl}-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C16H16F3IO3S, CAS 2680527-88-0
Ethyl 1-(iodomethyl)-3-{3-[(trifluoromethyl)sulfanyl]phenyl}-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2680527-88-0C16H16F3IO3S
1-(Bromomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane chemical structure, C12H13BrO, CAS 2703780-90-7
1-(Bromomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane
CAS 2703780-90-7C12H13BrO
Ethyl 1-(iodomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C15H17IO3, CAS 2763780-40-9
Ethyl 1-(iodomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2763780-40-9C15H17IO3
Methyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C14H17NO3, CAS 2639445-06-8
Methyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2639445-06-8C14H17NO3
tert-Butyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C17H23NO3, CAS 2639451-23-1
tert-Butyl 1-(aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2639451-23-1C17H23NO3
1-({[(tert-Butoxy)carbonyl]amino}methyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C18H23NO5, CAS 2639424-81-8
1-({[(tert-Butoxy)carbonyl]amino}methyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2639424-81-8C18H23NO5
1-(Aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C13H15NO3, CAS 2639437-07-1
1-(Aminomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2639437-07-1C13H15NO3
3-Phenyl-1-[(2,2,2-trifluoroacetamido)methyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C15H14F3NO4, CAS 2680694-18-0
3-Phenyl-1-[(2,2,2-trifluoroacetamido)methyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2680694-18-0C15H14F3NO4
1-(Acetamidomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C15H17NO4, CAS 2680786-73-4
1-(Acetamidomethyl)-3-phenyl-2-oxabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2680786-73-4C15H17NO4
Ethyl 3-[3,5-bis(trifluoromethyl)phenyl]-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C17H15F6IO3, CAS 2680543-29-5
Ethyl 3-[3,5-bis(trifluoromethyl)phenyl]-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2680543-29-5C17H15F6IO3
Ethyl 1-(iodomethyl)-3-[3-(trifluoromethoxy)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C16H16F3IO4, CAS 2680530-97-4
Ethyl 1-(iodomethyl)-3-[3-(trifluoromethoxy)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2680530-97-4C16H16F3IO4
Ethyl 3-(4-cyanophenyl)-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C16H16INO3, CAS 2694735-29-8
Ethyl 3-(4-cyanophenyl)-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2694735-29-8C16H16INO3
Ethyl 1-(iodomethyl)-3-(3-nitrophenyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C15H16INO5, CAS 2703782-00-5
Ethyl 1-(iodomethyl)-3-(3-nitrophenyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2703782-00-5C15H16INO5
Ethyl 1-(iodomethyl)-3-[4-(trifluoromethyl)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C16H16F3IO3, CAS 2703779-66-0
Ethyl 1-(iodomethyl)-3-[4-(trifluoromethyl)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2703779-66-0C16H16F3IO3
Ethyl 1-(iodomethyl)-3-[3-(pentafluoro-lambda6-sulfanyl)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C15H16F5IO3S, CAS 2703779-70-6
Ethyl 1-(iodomethyl)-3-[3-(pentafluoro-lambda6-sulfanyl)phenyl]-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2703779-70-6C15H16F5IO3S
Ethyl 1-(iodomethyl)-3-(4-methoxyphenyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate chemical structure, C16H19IO4, CAS 2703781-60-4
Ethyl 1-(iodomethyl)-3-(4-methoxyphenyl)-2-oxabicyclo[2.1.1]hexane-4-carboxylate
CAS 2703781-60-4C16H19IO4