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Murcko scaffold

Ring system with 4 rings and 27 atoms

57 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
57
With full pages
2
Scaffold SMILES

O=C(NCCOc1ccccc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCOc1ccccc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

4-(2-(Fmoc-amino)ethoxy)benzoic acid chemical structure, C24H21NO5, CAS 882847-29-2
4-(2-(Fmoc-amino)ethoxy)benzoic acid
CAS 882847-29-2C24H21NO5
(R)-a-Amino-3,5-dichlorobenzenebutanoic acid chemical structure, C25H23NO5, CAS 1629658-48-5
(R)-a-Amino-3,5-dichlorobenzenebutanoic acid
CAS 1629658-48-5C25H23NO5
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(2-phenoxyethyl)amino)-2-methylpropanoic acid chemical structure, C27H27NO5, CAS 2094456-49-0
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(2-phenoxyethyl)amino)-2-methylpropanoic acid
CAS 2094456-49-0C27H27NO5
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-fluorophenoxy)propanoic acid chemical structure, C24H20FNO5, CAS 2094502-34-6
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-fluorophenoxy)propanoic acid
CAS 2094502-34-6C24H20FNO5
Fmoc-Ser(O-(2-chlorophenyl))-OH chemical structure, C24H20ClNO5, CAS 1401662-79-0
Fmoc-Ser(O-(2-chlorophenyl))-OH
CAS 1401662-79-0C24H20ClNO5
N-Fmoc-O-(3-chlorophenyl)-L-serine chemical structure, C24H20ClNO5, CAS 2255321-08-3
N-Fmoc-O-(3-chlorophenyl)-L-serine
CAS 2255321-08-3C24H20ClNO5
Fmoc-(S)-2-amino-5-(3-methoxyphenyl)pentanoic acid chemical structure, C25H22ClNO5, CAS 2255321-15-2
Fmoc-(S)-2-amino-5-(3-methoxyphenyl)pentanoic acid
CAS 2255321-15-2C25H22ClNO5
N-Fmoc-N-(2-phenoxyethyl)glycine chemical structure, C25H23NO5, CAS 2255321-25-4
N-Fmoc-N-(2-phenoxyethyl)glycine
CAS 2255321-25-4C25H23NO5
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]benzoic acid chemical structure, C24H21NO5, CAS 2402829-01-8
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]benzoic acid
CAS 2402829-01-8C24H21NO5
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-phenyl-L-serine chemical structure, C24H21NO5, CAS 1401662-77-8
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-phenyl-L-serine
CAS 1401662-77-8C24H21NO5
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid chemical structure, C25H23NO5, CAS 2413899-69-9
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid
CAS 2413899-69-9C25H23NO5
5-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]-2-methylbenzoic acid chemical structure, C25H23NO5, CAS 2413899-32-6
5-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]-2-methylbenzoic acid
CAS 2413899-32-6C25H23NO5
3-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]-4-methylbenzoic acid chemical structure, C25H23NO5, CAS 2413875-48-4
3-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]-4-methylbenzoic acid
CAS 2413875-48-4C25H23NO5
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]-4-methoxybenzoic acid chemical structure, C25H23NO6, CAS 2408963-97-1
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]-4-methoxybenzoic acid
CAS 2408963-97-1C25H23NO6
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]-3-methoxybenzoic acid chemical structure, C25H23NO6, CAS 2416237-06-2
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]-3-methoxybenzoic acid
CAS 2416237-06-2C25H23NO6
2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid chemical structure, C25H23NO5, CAS 2416231-62-2
2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid
CAS 2416231-62-2C25H23NO5
N-Fmoc-O-phenyl-D-serine chemical structure, C24H21NO5
N-Fmoc-O-phenyl-D-serine
C24H21NO5
(R)-3-(Fmoc-amino)-4-phenoxybutanoic Acid chemical structure, C25H23NO5, CAS 2349622-28-0
(R)-3-(Fmoc-amino)-4-phenoxybutanoic Acid
CAS 2349622-28-0C25H23NO5
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenoxybutanoic acid chemical structure, C25H23NO5, CAS 2349484-02-0
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenoxybutanoic acid
CAS 2349484-02-0C25H23NO5
N-Fmoc-O-phenyl-L-threonine chemical structure, C25H23NO5, CAS 2559750-91-1
N-Fmoc-O-phenyl-L-threonine
CAS 2559750-91-1C25H23NO5
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-1,1-difluoroethoxy]benzoic acid chemical structure, C24H19F2NO5, CAS 2470435-92-6
3-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-1,1-difluoroethoxy]benzoic acid
CAS 2470435-92-6C24H19F2NO5
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-1,1-difluoroethoxy]benzoic acid chemical structure, C24H19F2NO5, CAS 2470438-92-5
4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-1,1-difluoroethoxy]benzoic acid
CAS 2470438-92-5C24H19F2NO5
(S)-a-Amino-2,4-dichlorobenzenebutanoic acid chemical structure, C24H20ClNO5, CAS 2350394-55-5
(S)-a-Amino-2,4-dichlorobenzenebutanoic acid
CAS 2350394-55-5C24H20ClNO5
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenoxy)propanoic acid chemical structure, C24H20FNO5
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenoxy)propanoic acid
C24H20FNO5