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Murcko scaffold

Ring system with 4 rings and 27 atoms

22 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 27
Chemicals: 22
With full pages: 2

Scaffold SMILES

O=C(NCCCc1ccncc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(NCCCc1ccncc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

(S)-N-Fmoc-[2-(4-pyridyl)ethyl]glycine chemical structure, C24H22N2O4, CAS 273222-04-1

(S)-N-Fmoc-[2-(4-pyridyl)ethyl]glycine

CAS 273222-04-1C₂₄H₂₂N₂O₄

Fmoc-(R)-2-amino-4-(pyridin-4-yl)butanoic acid chemical structure, C24H22N2O4, CAS 1260604-16-7

Fmoc-(R)-2-amino-4-(pyridin-4-yl)butanoic acid

CAS 1260604-16-7C₂₄H₂₂N₂O₄

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(pyridin-4-ylmethyl)propanoic acid chemical structure, C24H22N2O4, CAS 1260590-60-0

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(pyridin-4-ylmethyl)propanoic acid

CAS 1260590-60-0C₂₄H₂₂N₂O₄

(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(pyridin-4-ylmethyl)propanoic acid chemical structure, C24H22N2O4, CAS 1260607-22-4

(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(pyridin-4-ylmethyl)propanoic acid

CAS 1260607-22-4C₂₄H₂₂N₂O₄

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(pyridin-4-yl)butanoic acid chemical structure, C24H22N2O4, CAS 273222-02-9

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(pyridin-4-yl)butanoic acid

CAS 273222-02-9C₂₄H₂₂N₂O₄

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((pyridin-4-yl)methyl)propanoic acid chemical structure, C24H22N2O4, CAS 1823652-01-2

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((pyridin-4-yl)methyl)propanoic acid

CAS 1823652-01-2C₂₄H₂₂N₂O₄

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-(pyridin-4-yl)butanoic acid chemical structure, C25H24N2O4, CAS 2642331-43-7

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-(pyridin-4-yl)butanoic acid

CAS 2642331-43-7C₂₅H₂₄N₂O₄

4-[(3-{[(tert-Butoxy)carbonyl]amino}-2-[(pyridin-4-yl)methyl]propyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]butanoic acid chemical structure, C33H39N3O6, CAS 2138547-02-9

4-[(3-{[(tert-Butoxy)carbonyl]amino}-2-[(pyridin-4-yl)methyl]propyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]butanoic acid

CAS 2138547-02-9C₃₃H₃₉N₃O₆

(9H-Fluoren-9-yl)methyl N-[1-hydroxy-4-(pyridin-4-yl)butan-2-yl]carbamate chemical structure, C24H24N2O3, CAS 2763916-11-4

(9H-Fluoren-9-yl)methyl N-[1-hydroxy-4-(pyridin-4-yl)butan-2-yl]carbamate

CAS 2763916-11-4C₂₄H₂₄N₂O₃

(9H-Fluoren-9-yl)methyl N-{2-[(3-chloropyridin-4-yl)methyl]-3-hydroxypropyl}carbamate chemical structure, C24H23ClN2O3, CAS 2763998-07-6

(9H-Fluoren-9-yl)methyl N-{2-[(3-chloropyridin-4-yl)methyl]-3-hydroxypropyl}carbamate

CAS 2763998-07-6C₂₄H₂₃ClN₂O₃

(9H-Fluoren-9-yl)methyl N-{3-hydroxy-2-[(pyridin-4-yl)methyl]propyl}carbamate chemical structure, C24H24N2O3, CAS 2763923-33-5

(9H-Fluoren-9-yl)methyl N-{3-hydroxy-2-[(pyridin-4-yl)methyl]propyl}carbamate

CAS 2763923-33-5C₂₄H₂₄N₂O₃

(S)-2-(Fmoc-amino)-4-(2-methylpyridin-4-yl)butanoic acid chemical structure, C25H24N2O4, CAS 2350818-75-4

(S)-2-(Fmoc-amino)-4-(2-methylpyridin-4-yl)butanoic acid

CAS 2350818-75-4C₂₅H₂₄N₂O₄

(S)-2-(Fmoc-amino)-4-(2-fluoropyridin-4-yl)butanoic acid chemical structure, C24H21FN2O4, CAS 2350486-55-2

(S)-2-(Fmoc-amino)-4-(2-fluoropyridin-4-yl)butanoic acid

CAS 2350486-55-2C₂₄H₂₁FN₂O₄

Fmoc-4-(3-methylpyridin-4-yl)-Abu-OH chemical structure, C25H24N2O4, CAS 2349891-63-8

Fmoc-4-(3-methylpyridin-4-yl)-Abu-OH

CAS 2349891-63-8C₂₅H₂₄N₂O₄

(S)-a-(Fmoc-amino)-2-methoxy-4-pyridinebutanoic acid chemical structure, C25H24N2O5, CAS 2349735-87-9

(S)-a-(Fmoc-amino)-2-methoxy-4-pyridinebutanoic acid

CAS 2349735-87-9C₂₅H₂₄N₂O₅

Fmoc-(S)-2-amino-4-(3-methoxypyridin-4-yl)butyric acid chemical structure, C25H24N2O5, CAS 2349487-07-4

Fmoc-(S)-2-amino-4-(3-methoxypyridin-4-yl)butyric acid

CAS 2349487-07-4C₂₅H₂₄N₂O₅

(S)-a-(Fmoc-amino)-3-fluoro-4-pyridinebutanoic acid chemical structure, C24H21FN2O4, CAS 2349346-76-3

(S)-a-(Fmoc-amino)-3-fluoro-4-pyridinebutanoic acid

CAS 2349346-76-3C₂₄H₂₁FN₂O₄

(S)-a-(Fmoc-amino)-2,3-difluoro-4-pyridinebutanoic acid chemical structure, C24H20F2N2O4, CAS 2349318-64-3

(S)-a-(Fmoc-amino)-2,3-difluoro-4-pyridinebutanoic acid

CAS 2349318-64-3C₂₄H₂₀F₂N₂O₄

Fmoc-(S)-2-amino-4-(3-chloropyridin-4-yl)butanoic acid chemical structure, C24H21ClN2O4, CAS 2350111-24-7

Fmoc-(S)-2-amino-4-(3-chloropyridin-4-yl)butanoic acid

CAS 2350111-24-7C₂₄H₂₁ClN₂O₄

(2S)-4-(3,5-Dimethoxy-4-pyridinyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid chemical structure, C26H26N2O6, CAS 2349581-76-4

(2S)-4-(3,5-Dimethoxy-4-pyridinyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid

CAS 2349581-76-4C₂₆H₂₆N₂O₆

(2S)-4-(3,5-Difluoro-4-pyridinyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid chemical structure, C24H20F2N2O4, CAS 2350658-87-4

(2S)-4-(3,5-Difluoro-4-pyridinyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid

CAS 2350658-87-4C₂₄H₂₀F₂N₂O₄

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-[3-(trifluoromethyl)-4-pyridinyl]butanoic acid chemical structure, C25H21F3N2O4, CAS 2349925-90-0

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-[3-(trifluoromethyl)-4-pyridinyl]butanoic acid

CAS 2349925-90-0C₂₅H₂₁F₃N₂O₄