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Murcko scaffold

Ring system with 4 rings and 20 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
11
With full pages
3
Scaffold SMILES

O=c1[nH]c2cccc(-c3ccccc3)c2c2ccsc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2cccc(-c3ccccc3)c2c2ccsc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

9-[4-[(2S)-1-Aminopropan-2-yl]phenyl]-8-hydroxy-6-methyl-5H-thieno[2,3-c]quinolin-4-one chemical structure, C21H20N2O2S, CAS 1338541-25-5
9-[4-[(2S)-1-Aminopropan-2-yl]phenyl]-8-hydroxy-6-methyl-5H-thieno[2,3-c]quinolin-4-one
CAS 1338541-25-5C21H20N2O2S
Ots964 chemical structure, C23H24N2O2S, CAS 1338542-14-5
Ots964
CAS 1338542-14-5C23H24N2O2S
Pbk-IN-9 chemical structure, C20H18N2O2S, CAS 1338540-55-8
Pbk-IN-9
CAS 1338540-55-8C20H18N2O2S
9-[4-(2-Aminopropan-2-yl)phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one chemical structure, C21H20N2O2S, CAS 1338542-20-3
9-[4-(2-Aminopropan-2-yl)phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
CAS 1338542-20-3C21H20N2O2S
(R)-9-(4-(1-Aminopropan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one chemical structure, C21H20N2O2S, CAS 1338540-63-8
(R)-9-(4-(1-Aminopropan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
CAS 1338540-63-8C21H20N2O2S
tert-Butyl (R)-(2-(4-(8-methoxy-6-methyl-4-oxo-4,5-dihydrothieno[2,3-C]quinolin-9-yl)phenyl)propyl)carbamate chemical structure, C27H30N2O4S, CAS 1338544-43-6
tert-Butyl (R)-(2-(4-(8-methoxy-6-methyl-4-oxo-4,5-dihydrothieno[2,3-C]quinolin-9-yl)phenyl)propyl)carbamate
CAS 1338544-43-6C27H30N2O4S
(R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxythieno[2,3-c]quinolin-4(5H)-one hydrochloride chemical structure, C22H23ClN2O2S, CAS 1338545-01-9
(R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxythieno[2,3-c]quinolin-4(5H)-one hydrochloride
CAS 1338545-01-9C22H23ClN2O2S
(R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxythieno(2,3-c)quinolin-4(5H)-one chemical structure, C22H22N2O2S, CAS 1338540-81-0
(R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxythieno(2,3-c)quinolin-4(5H)-one
CAS 1338540-81-0C22H22N2O2S
(R)-9-(4-(1-Aminopropan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrobromide chemical structure, C21H21BrN2O2S, CAS 1338544-87-8
(R)-9-(4-(1-Aminopropan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrobromide
CAS 1338544-87-8C21H21BrN2O2S
OTS964 hydrochloride chemical structure, C23H25ClN2O2S, CAS 1338545-07-5
OTS964 hydrochloride
CAS 1338545-07-5C23H25ClN2O2S
OTS514 hydrochloride chemical structure, C21H21ClN2O2S, CAS 2319647-76-0
OTS514 hydrochloride
CAS 2319647-76-0C21H21ClN2O2S