Murcko scaffold

Pyroquilon scaffold

43 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 13
Chemicals: 43
With full pages: 27

Scaffold SMILES

O=C1CCc2cccc3c2N1CC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Pyroquilon page

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

Pyroquilon

CAS 57369-32-1C₁₁H₁₁NO

3,3-Dimethyl-N-(4-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)butanamide

CAS 898453-47-9C₁₇H₂₂N₂O₂

$3-Methyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}butanamide chemical structure, C16H20N2O2, CAS 903292-18-2$

3-Methyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}butanamide

CAS 903292-18-2C₁₆H₂₀N₂O₂

$N-{11-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}acetamide chemical structure, C13H14N2O2, CAS 903366-29-0$

N-{11-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}acetamide

CAS 903366-29-0C₁₃H₁₄N₂O₂

$2,2-Dimethyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}propanamide chemical structure, C16H20N2O2, CAS 898418-71-8$

2,2-Dimethyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}propanamide

CAS 898418-71-8C₁₆H₂₀N₂O₂

N-(4-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)propionamide

CAS 898435-23-9C₁₄H₁₆N₂O₂

$2-Methyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}propanamide chemical structure, C15H18N2O2, CAS 898461-87-5$

2-Methyl-N-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}propanamide

CAS 898461-87-5C₁₅H₁₈N₂O₂

N-(4-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)ethanesulfonamide

CAS 898418-83-2C₁₃H₁₆N₂O₃S

$11-Oxo-N-propyl-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C14H18N2O3S, CAS 898435-91-1$

11-Oxo-N-propyl-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898435-91-1C₁₄H₁₈N₂O₃S

$11-Oxo-N-(prop-2-en-1-yl)-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C14H16N2O3S, CAS 898462-46-9$

11-Oxo-N-(prop-2-en-1-yl)-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-46-9C₁₄H₁₆N₂O₃S

$N-(3-Methylbutyl)-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C16H22N2O3S, CAS 898419-43-7$

N-(3-Methylbutyl)-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898419-43-7C₁₆H₂₂N₂O₃S

N-Butyl-4-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898435-93-3C₁₅H₂₀N₂O₃S

$11-Oxo-N-pentyl-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C16H22N2O3S, CAS 903308-42-9$

11-Oxo-N-pentyl-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 903308-42-9C₁₆H₂₂N₂O₃S

$N-(2,2-Dimethoxyethyl)-N-methyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C16H22N2O5S, CAS 898419-51-7$

N-(2,2-Dimethoxyethyl)-N-methyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898419-51-7C₁₆H₂₂N₂O₅S

4-Oxo-N,N-dipropyl-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898419-53-9C₁₇H₂₄N₂O₃S

$N-(2,2-Dimethoxyethyl)-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C15H20N2O5S, CAS 898462-64-1$

N-(2,2-Dimethoxyethyl)-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-64-1C₁₅H₂₀N₂O₅S

$N-(2-Cyanoethyl)-N-methyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C15H17N3O3S, CAS 898462-96-9$

N-(2-Cyanoethyl)-N-methyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-96-9C₁₅H₁₇N₃O₃S

$N-tert-Butyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C15H20N2O3S, CAS 898462-98-1$

N-tert-Butyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-98-1C₁₅H₂₀N₂O₃S

$N-[2-(Dimethylamino)ethyl]-N'-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}ethanediamide chemical structure, C17H22N4O3, CAS 898418-90-1$

N-[2-(Dimethylamino)ethyl]-N'-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}ethanediamide

CAS 898418-90-1C₁₇H₂₂N₄O₃

$N-(2-Hydroxyethyl)-N'-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}ethanediamide chemical structure, C15H17N3O4, CAS 898462-11-8$

N-(2-Hydroxyethyl)-N'-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}ethanediamide

CAS 898462-11-8C₁₅H₁₇N₃O₄

$N-(2,2-Dimethoxyethyl)-N'-{11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}ethanediamide chemical structure, C17H21N3O5, CAS 898462-14-1$