Murcko scaffold

5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one scaffold

51 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 13
Chemicals: 51
With full pages: 23

Scaffold SMILES

O=C1Cc2cccc3c2N1CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one page

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

1-(Methylsulfanyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one

CAS 88426-30-6C₁₂H₁₃NOS

8-(2-Chloroacetyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one

CAS 847744-24-5C₁₃H₁₂ClNO₂

$N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}methanesulfonamide chemical structure, C12H14N2O3S, CAS 898426-64-7$

N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}methanesulfonamide

CAS 898426-64-7C₁₂H₁₄N₂O₃S

N-(2-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)ethanesulfonamide

CAS 898426-66-9C₁₃H₁₆N₂O₃S

$N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}butanamide chemical structure, C15H18N2O2, CAS 898436-52-7$

N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}butanamide

CAS 898436-52-7C₁₅H₁₈N₂O₂

$3,3-Dimethyl-N-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}butanamide chemical structure, C17H22N2O2, CAS 898420-03-6$

3,3-Dimethyl-N-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}butanamide

CAS 898420-03-6C₁₇H₂₂N₂O₂

$2-Methoxy-N-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}acetamide chemical structure, C14H16N2O3, CAS 898436-72-1$

2-Methoxy-N-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}acetamide

CAS 898436-72-1C₁₄H₁₆N₂O₃

$N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}acetamide chemical structure, C13H14N2O2, CAS 898410-73-6$

N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}acetamide

CAS 898410-73-6C₁₃H₁₄N₂O₂

N-(2-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)pivalamide

CAS 898463-46-2C₁₆H₂₀N₂O₂

$N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}propanamide chemical structure, C14H16N2O2, CAS 898436-74-3$

N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}propanamide

CAS 898436-74-3C₁₄H₁₆N₂O₂

N-(2-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)isobutyramide

CAS 898410-75-8C₁₅H₁₈N₂O₂

$N-[2-(Diethylamino)ethyl]-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide chemical structure, C19H26N4O3, CAS 898454-64-3$

N-[2-(Diethylamino)ethyl]-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide

CAS 898454-64-3C₁₉H₂₆N₄O₃

N1-isopentyl-N2-(2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)oxalamide

CAS 898454-66-5C₁₈H₂₃N₃O₃

N1-(2-(dimethylamino)ethyl)-N2-(2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)oxalamide

CAS 898411-18-2C₁₇H₂₂N₄O₃

$N-[3-(Dimethylamino)propyl]-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide chemical structure, C18H24N4O3, CAS 898426-88-5$

N-[3-(Dimethylamino)propyl]-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide

CAS 898426-88-5C₁₈H₂₄N₄O₃

$N-Butyl-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide chemical structure, C17H21N3O3, CAS 898454-67-6$

N-Butyl-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide

CAS 898454-67-6C₁₇H₂₁N₃O₃

N1-(2-methoxyethyl)-N2-(2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)oxalamide

CAS 898411-19-3C₁₆H₁₉N₃O₄

$N'-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}-N-pentylethanediamide chemical structure, C18H23N3O3, CAS 898426-90-9$

N'-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}-N-pentylethanediamide

CAS 898426-90-9C₁₈H₂₃N₃O₃

N1-(3-hydroxypropyl)-N2-(2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)oxalamide

CAS 898411-22-8C₁₆H₁₉N₃O₄

$N-(2,2-Dimethoxyethyl)-N'-{2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}ethanediamide chemical structure, C17H21N3O5, CAS 898454-71-2$