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Murcko scaffold

4-(Benzenesulfonyl)-N-[3-(morpholin-4-yl)propyl]-2-phenyl-1,3-oxazol-5-amine scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
10
With full pages
6
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nc(-c2ccccc2)oc1NCCCN1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Benzenesulfonyl)-N-[3-(morpholin-4-yl)propyl]-2-phenyl-1,3-oxazol-5-amine page
Murcko scaffold O=S(=O)(c1ccccc1)c1nc(-c2ccccc2)oc1NCCCN1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(4-Chlorophenyl)-4-(4-methylphenyl)sulfonyl-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine chemical structure, C23H26ClN3O4S, CAS 630084-48-9
2-(4-Chlorophenyl)-4-(4-methylphenyl)sulfonyl-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine
CAS 630084-48-9C23H26ClN3O4S
4-(Benzenesulfonyl)-2-(4-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine chemical structure, C22H24ClN3O4S, CAS 378193-59-0
4-(Benzenesulfonyl)-2-(4-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine
CAS 378193-59-0C22H24ClN3O4S
4-(Benzenesulfonyl)-N-[3-(morpholin-4-yl)propyl]-2-phenyl-1,3-oxazol-5-amine chemical structure, C22H25N3O4S, CAS 380318-39-8
4-(Benzenesulfonyl)-N-[3-(morpholin-4-yl)propyl]-2-phenyl-1,3-oxazol-5-amine
CAS 380318-39-8C22H25N3O4S
2-(2-Chlorophenyl)-4-[(4-methylphenyl)sulfonyl]-N-[3-(morpholin-4-yl)propyl]-1,3-oxazol-5-amine chemical structure, C23H26ClN3O4S, CAS 380190-61-4
2-(2-Chlorophenyl)-4-[(4-methylphenyl)sulfonyl]-N-[3-(morpholin-4-yl)propyl]-1,3-oxazol-5-amine
CAS 380190-61-4C23H26ClN3O4S
4-(4-Methylphenyl)sulfonyl-N-(3-morpholin-4-ylpropyl)-2-phenyl-1,3-oxazol-5-amine chemical structure, C23H27N3O4S, CAS 377766-03-5
4-(4-Methylphenyl)sulfonyl-N-(3-morpholin-4-ylpropyl)-2-phenyl-1,3-oxazol-5-amine
CAS 377766-03-5C23H27N3O4S
4-(Benzenesulfonyl)-2-(2-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine chemical structure, C22H24ClN3O4S, CAS 380319-71-1
4-(Benzenesulfonyl)-2-(2-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine
CAS 380319-71-1C22H24ClN3O4S
4-(Benzenesulfonyl)-2-(4-methoxyphenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine chemical structure, C23H27N3O5S, CAS 855714-97-5
4-(Benzenesulfonyl)-2-(4-methoxyphenyl)-N-(3-morpholin-4-ylpropyl)-1,3-oxazol-5-amine
CAS 855714-97-5C23H27N3O5S
N-(3-Morpholinopropyl)-4-(phenylsulfonyl)-2-(p-tolyl)oxazol-5-amine chemical structure, C23H27N3O4S, CAS 862737-83-5
N-(3-Morpholinopropyl)-4-(phenylsulfonyl)-2-(p-tolyl)oxazol-5-amine
CAS 862737-83-5C23H27N3O4S
4-((4-Fluorophenyl)sulfonyl)-N-(3-morpholinopropyl)-2-phenyloxazol-5-amine chemical structure, C22H24FN3O4S, CAS 862737-81-3
4-((4-Fluorophenyl)sulfonyl)-N-(3-morpholinopropyl)-2-phenyloxazol-5-amine
CAS 862737-81-3C22H24FN3O4S
N-(3-Morpholinopropyl)-4-(phenylsulfonyl)-2-(m-tolyl)oxazol-5-amine chemical structure, C23H27N3O4S, CAS 862737-97-1
N-(3-Morpholinopropyl)-4-(phenylsulfonyl)-2-(m-tolyl)oxazol-5-amine
CAS 862737-97-1C23H27N3O4S