Murcko scaffold
1,2,4-Triazolo(4,3-c)pyrimidine scaffold
75 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 75
- With full pages
- 14
Scaffold SMILES
c1cc2nncn2cn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 75 chemicals
![7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine-3,8-diamine chemical structure, C5H5ClN6, CAS 7252-17-7](/s/LBAZMWQDPLRPTI-UHFFFAOYSA-N.svg)
7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine-3,8-diamine
CAS 7252-17-7C5H5ClN6
![3-Ethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4, CAS 69141-79-3](/s/JEULMYQFDRWNML-UHFFFAOYSA-N.svg)
3-Ethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-79-3C7H8N4
![5,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4, CAS 69141-85-1](/s/LVHOTFUNLPCHEX-UHFFFAOYSA-N.svg)
5,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-85-1C7H8N4
![3,5-Dimethyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4, CAS 69141-87-3](/s/HUHPDOSHTABGAX-UHFFFAOYSA-N.svg)
3,5-Dimethyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-87-3C7H8N4
![7,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4, CAS 69141-89-5](/s/ALMOPDODCWSXST-UHFFFAOYSA-N.svg)
7,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-89-5C7H8N4
![3,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4, CAS 69141-95-3](/s/PGKIAPKTVDHXSM-UHFFFAOYSA-N.svg)
3,8-Dimethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-95-3C7H8N4
![5,7,8-Trimethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C8H10N4, CAS 69141-97-5](/s/IWEGKCHOPNXGOI-UHFFFAOYSA-N.svg)
5,7,8-Trimethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-97-5C8H10N4
![3,5,7-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C8H10N4, CAS 69141-99-7](/s/KUARDUMXESYJMB-UHFFFAOYSA-N.svg)
3,5,7-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-99-7C8H10N4
![3,5,8-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C8H10N4, CAS 342617-17-8](/s/JIPITZBXQAOBBA-UHFFFAOYSA-N.svg)
3,5,8-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 342617-17-8C8H10N4
![3,5,7,8-Tetramethyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C9H12N4, CAS 69142-14-9](/s/BBDBEBRPLICLBI-UHFFFAOYSA-N.svg)
3,5,7,8-Tetramethyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69142-14-9C9H12N4
![3-Ethyl-5,7,8-trimethyl[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C10H14N4, CAS 69142-15-0](/s/KIGIZPVGEICIQI-UHFFFAOYSA-N.svg)
3-Ethyl-5,7,8-trimethyl[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69142-15-0C10H14N4
![3,7,8-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C8H10N4, CAS 342617-23-6](/s/JWXXGEAXASXGPO-UHFFFAOYSA-N.svg)
3,7,8-Trimethyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 342617-23-6C8H10N4
1,2,4-Triazolo(4,3-c)pyrimidine
CAS 274-81-7C5H4N4
![7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidin-8-amine chemical structure, C5H4ClN5, CAS 7498-26-2](/s/JJRMZBCFIRABIK-UHFFFAOYSA-N.svg)
7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidin-8-amine
CAS 7498-26-2C5H4ClN5
![Ethyl (7-chloro[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)methanimidate chemical structure, C8H8ClN5O, CAS 92385-17-6](/s/MTLZMIMTHNMUMU-UHFFFAOYSA-N.svg)
Ethyl (7-chloro[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)methanimidate
CAS 92385-17-6C8H8ClN5O
![8-Methoxy-3-methyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H8N4O, CAS 106921-51-1](/s/UUHKQXSQHFXTCN-UHFFFAOYSA-N.svg)
8-Methoxy-3-methyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 106921-51-1C7H8N4O
![7-Methyl-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C6H6N4, CAS 69141-72-6](/s/OXKJOXHMEAWGNG-UHFFFAOYSA-N.svg)
7-Methyl-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 69141-72-6C6H6N4
![8-Bromo-3-methyl-5-(methylthio)-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C7H7BrN4S, CAS 99451-54-4](/s/CNNTZQFFZGBPQL-UHFFFAOYSA-N.svg)
8-Bromo-3-methyl-5-(methylthio)-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 99451-54-4C7H7BrN4S
![8-Bromo-5-(methylthio)[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C6H5BrN4S, CAS 99451-55-5](/s/PYXSQRIHTWWWIN-UHFFFAOYSA-N.svg)
8-Bromo-5-(methylthio)[1,2,4]triazolo[4,3-c]pyrimidine
CAS 99451-55-5C6H5BrN4S
![8-Fluoro-5-(methylthio)-[1,2,4]triazolo[4,3-C]pyrimidine chemical structure, C6H5FN4S, CAS 99451-63-5](/s/YHVGCHJNTJXUBD-UHFFFAOYSA-N.svg)
8-Fluoro-5-(methylthio)-[1,2,4]triazolo[4,3-C]pyrimidine
CAS 99451-63-5C6H5FN4S
![8-Chloro-5-(methylthio)-[1,2,4]triazolo[4,3-C]pyrimidine chemical structure, C6H5ClN4S, CAS 99451-65-7](/s/NZOWPFRTHXVCKQ-UHFFFAOYSA-N.svg)
8-Chloro-5-(methylthio)-[1,2,4]triazolo[4,3-C]pyrimidine
CAS 99451-65-7C6H5ClN4S
![5-Chloro-7-methyl-1,2,4-triazolo[4,3-c]pyrimidine chemical structure, C6H5ClN4, CAS 56881-37-9](/s/IINGUEVVOQIUIO-UHFFFAOYSA-N.svg)
5-Chloro-7-methyl-1,2,4-triazolo[4,3-c]pyrimidine
CAS 56881-37-9C6H5ClN4
![7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C5H3ClN4, CAS 923191-97-3](/s/NXPWNUDUDIHZQC-UHFFFAOYSA-N.svg)
7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine
CAS 923191-97-3C5H3ClN4
(1,2,4)Triazolo(4,3-c)pyrimidin-3-amine
CAS 859765-68-7C5H5N5
- 7-Methyl[1,2,4]triazolo[4,3-c]pyrimidin-5-amine1023815-95-3C6H7N5
- N-(1-Cyano-1,2-dimethylpropyl)-2-({5,7-dimethyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-yl}sulfanyl)acetamide1147651-84-0C15H20N6OS
- 7-Chloro-3-ethyl-[1,2,4]triazolo[4,3-c]pyrimidine1094260-61-3C7H7ClN4
- 7-Chloro-3-(propan-2-yl)-(1,2,4)triazolo(4,3-c)pyrimidine1094425-28-1C8H9ClN4
- 3-tert-Butyl-7-chloro-[1,2,4]triazolo[4,3-c]pyrimidine1094292-89-3C9H11ClN4
- 7-Chloro-3-methyl-[1,2,4]triazolo[4,3-c]pyrimidine1094292-91-7C6H5ClN4
- 7-Chloro-3-propyl-[1,2,4]triazolo[4,3-c]pyrimidine1152578-03-4C8H9ClN4
- 7-Chloro-3-(1-ethylpentyl)-1,2,4-triazolo[4,3-c]pyrimidine1094260-91-9C12H17ClN4
- 7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidin-3-amine1306605-83-3C5H4ClN5
- 7-Chloro-5-methyl-[1,2,4]triazolo[4,3-c]pyrimidine1354951-50-0C6H5ClN4
- 7-Chloro[1,2,4]triazolo[4,3-c]pyrimidin-5-amine1306739-68-3C5H4ClN5
- {7-Chloro-[1,2,4]triazolo[4,3-c]pyrimidin-3-yl}methanol1183462-18-1C6H5ClN4O
- 7-Hydrazinyl-[1,2,4]triazolo[4,3-c]pyrimidine1184281-36-4C5H6N6
- Ethyl 7-methyl-[1,2,4]triazolo[4,3-c]pyrimidine-3-carboxylate1341283-98-4C9H10N4O2
- 8-Bromo-(1,2,4)triazolo(4,3-c)pyrimidine1208084-77-8C5H3BrN4
- 8-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine1208083-81-1C5H3ClN4
- 8-Iodo-[1,2,4]triazolo[4,3-c]pyrimidine1208089-76-2C5H3IN4
- Ethyl (1,2,4)triazolo(4,3-c)pyrimidine-3-carboxylate1518418-22-8C8H8N4O2
- 7-Methyl[1,2,4]triazolo[4,3-c]pyrimidin-3-amine117888-94-5C6H7N5
- 7-Methyl-[1,2,4]triazolo[4,3-c]pyrimidine-3-carboxylic acid1283877-26-8C7H6N4O2
- 7-Chloro-5-methyl-3-(propoxymethyl)[1,2,4]triazolo[4,3-c]pyrimidine1702230-02-1C10H13ClN4O
- [1,2,4]Triazolo[4,3-c]pyrimidin-5-amine1823337-74-1C5H5N5
- 5-Chloro-8-fluoro[1,2,4]triazolo[4,3-c]pyrimidine1417360-98-5C5H2ClFN4
- 5-Chloro-[1,2,4]triazolo[4,3-C]pyrimidine1936595-47-9C5H3ClN4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals