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Murcko scaffold

5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine] scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
11
Chemicals
13
With full pages
1
Scaffold SMILES

c1cc2n(n1)CC1(CC1)CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine] page
Murcko scaffold c1cc2n(n1)CC1(CC1)CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazine]-2'-carboxylic acid chemical structure, C9H10N2O3, CAS 1428234-37-0
5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazine]-2'-carboxylic acid
CAS 1428234-37-0C9H10N2O3
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-3'-carboxylic acid chemical structure, C9H10N2O3, CAS 1428234-33-6
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-3'-carboxylic acid
CAS 1428234-33-6C9H10N2O3
3'-Bromo-5'H,7'H-spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine] chemical structure, C8H9BrN2O, CAS 1785105-75-0
3'-Bromo-5'H,7'H-spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine]
CAS 1785105-75-0C8H9BrN2O
2'-Bromo-5',7'-dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-3'-carbaldehyde chemical structure, C9H9BrN2O2, CAS 1785004-48-9
2'-Bromo-5',7'-dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-3'-carbaldehyde
CAS 1785004-48-9C9H9BrN2O2
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazin]-3'-amine chemical structure, C8H11N3O, CAS 1779129-70-2
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazin]-3'-amine
CAS 1779129-70-2C8H11N3O
Spiro[5,7-dihydropyrazolo[5,1-b][1,3]oxazine-6,1'-cyclopropane]-2-amine chemical structure, C8H11N3O, CAS 1707358-72-2
Spiro[5,7-dihydropyrazolo[5,1-b][1,3]oxazine-6,1'-cyclopropane]-2-amine
CAS 1707358-72-2C8H11N3O
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-5'-ylmethanamine hydrochloride chemical structure, C9H14ClN3O, CAS 2251053-61-7
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-5'-ylmethanamine hydrochloride
CAS 2251053-61-7C9H14ClN3O
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-6'-ylmethanamine hydrochloride chemical structure, C9H14ClN3O, CAS 2251053-39-9
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-6'-ylmethanamine hydrochloride
CAS 2251053-39-9C9H14ClN3O
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-6'-amine hydrochloride chemical structure, C8H12ClN3O, CAS 2251054-05-2
1',3'-Dihydrospiro{cyclopropane-1,2'-pyrazolo[3,2-b][1,3]oxazine}-6'-amine hydrochloride
CAS 2251054-05-2C8H12ClN3O
5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazine]-3'-sulfonamide chemical structure, C8H11N3O3S, CAS 2238821-17-3
5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazine]-3'-sulfonamide
CAS 2238821-17-3C8H11N3O3S
5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine] chemical structure, C8H10N2O, CAS 57290-46-7
5'H,7'H-Spiro[cyclopropane-1,6'-pyrazolo[5,1-B][1,3]oxazine]
CAS 57290-46-7C8H10N2O
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-2'-carbaldehyde chemical structure, C9H10N2O2, CAS 2803852-78-8
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazine]-2'-carbaldehyde
CAS 2803852-78-8C9H10N2O2
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazin]-3'-amine dihydrochloride chemical structure, C8H13Cl2N3O, CAS 3048758-33-1
5',7'-Dihydrospiro[cyclopropane-1,6'-pyrazolo[3,2-b][1,3]oxazin]-3'-amine dihydrochloride
CAS 3048758-33-1C8H13Cl2N3O