CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
10
With full pages
0
Scaffold SMILES

O=C1CCCC(CCC2CCC=C3C=CCCC32)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(CCC2CCC=C3C=CCCC32)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1,2,6,7,8,8a-Hexahydro-6-hydroxy-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate chemical structure, C23H34O6, CAS 81093-44-9
1,2,6,7,8,8a-Hexahydro-6-hydroxy-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate
CAS 81093-44-9C23H34O6
(4S,4aR,5S,6S)-4-(2,2-Dimethylbutanoyloxy)-5-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-6-methyl-3,4,4a,5,6,7-hexahydronaphthalene-2-carboxylic acid chemical structure, C25H36O7, CAS 125206-31-7
(4S,4aR,5S,6S)-4-(2,2-Dimethylbutanoyloxy)-5-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-6-methyl-3,4,4a,5,6,7-hexahydronaphthalene-2-carboxylic acid
CAS 125206-31-7C25H36O7
(1S,6S,7R,8S,8aR)-6-Hydroperoxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate chemical structure, C25H38O7, CAS 149949-01-9
(1S,6S,7R,8S,8aR)-6-Hydroperoxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
CAS 149949-01-9C25H38O7
3'(S)-hydroxy simvastatin chemical structure, C25H38O6, CAS 133645-46-2
3'(S)-hydroxy simvastatin
CAS 133645-46-2C25H38O6
3a-Hydroxy pravastatin lactone chemical structure, C23H34O6
3a-Hydroxy pravastatin lactone
C23H34O6
3beta-Hydroxy pravastatin lactone chemical structure, C23H34O6, CAS 87984-67-6
3beta-Hydroxy pravastatin lactone
CAS 87984-67-6C23H34O6
6-Carboxy -5',4',5,6-simvastatin-d6 chemical structure, C25H36O7, CAS 1346600-14-3
6-Carboxy -5',4',5,6-simvastatin-d6
CAS 1346600-14-3C25H36O7
6-Hydroxyisocompactin chemical structure, C23H34O6, CAS 85798-96-5
6-Hydroxyisocompactin
CAS 85798-96-5C23H34O6
[(1R,6R,7R,8S,8aR)-6-Hydroxy-8-[2-[(2R,4S)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate chemical structure, C23H34O6
[(1R,6R,7R,8S,8aR)-6-Hydroxy-8-[2-[(2R,4S)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
C23H34O6
3alpha-Hydroxy Pravastatin Lactone-d3 chemical structure, C23H34O6, CAS 1329809-35-9
3alpha-Hydroxy Pravastatin Lactone-d3
CAS 1329809-35-9C23H34O6