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Murcko scaffold

Ring system with 3 rings and 20 atoms

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
25
With full pages
6
Scaffold SMILES

O=C(CSc1n[nH]c(-c2ccco2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1n[nH]c(-c2ccco2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

2-[[5-(Furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-hydroxyphenyl)ethanone chemical structure, C15H13N3O3S, CAS 442659-84-9
2-[[5-(Furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-hydroxyphenyl)ethanone
CAS 442659-84-9C15H13N3O3S
1-(3,4-Dihydroxyphenyl)-2-[[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C14H11N3O4S, CAS 430444-03-4
1-(3,4-Dihydroxyphenyl)-2-[[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 430444-03-4C14H11N3O4S
1-(4-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C15H12FN3O2S, CAS 498550-91-7
1-(4-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 498550-91-7C15H12FN3O2S
2-[[4-Ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone chemical structure, C16H14FN3O2S, CAS 603981-61-9
2-[[4-Ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone
CAS 603981-61-9C16H14FN3O2S
2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethan-1-one chemical structure, C17H17N3O3S, CAS 603981-65-3
2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethan-1-one
CAS 603981-65-3C17H17N3O3S
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C15H13N3O2S, CAS 569644-81-1
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 569644-81-1C15H13N3O2S
1-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one chemical structure, C15H12ClN3O2S, CAS 569644-75-3
1-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one
CAS 569644-75-3C15H12ClN3O2S
1-(4-Chlorophenyl)-2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C16H14ClN3O2S, CAS 603981-59-5
1-(4-Chlorophenyl)-2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 603981-59-5C16H14ClN3O2S
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone chemical structure, C16H15N3O3S, CAS 498550-79-1
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone
CAS 498550-79-1C16H15N3O3S
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C17H15N3O2S, CAS 496971-96-1
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 496971-96-1C17H15N3O2S
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-fluorophenyl)ethanone chemical structure, C17H14FN3O2S, CAS 577788-11-5
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-fluorophenyl)ethanone
CAS 577788-11-5C17H14FN3O2S
2-[[5-(Furan-2-yl)-4-(2-methylprop-2-enyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone chemical structure, C19H19N3O3S, CAS 5867-32-3
2-[[5-(Furan-2-yl)-4-(2-methylprop-2-enyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone
CAS 5867-32-3C19H19N3O3S
1-(4-Bromophenyl)-2-{[5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C15H12BrN3O2S, CAS 384859-08-9
1-(4-Bromophenyl)-2-{[5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 384859-08-9C15H12BrN3O2S
1-(4-Bromophenyl)-2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C16H14BrN3O2S, CAS 678541-15-6
1-(4-Bromophenyl)-2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 678541-15-6C16H14BrN3O2S
Ethanone, 1-(2,4-dimethoxyphenyl)-2-[[4-ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]- chemical structure, C18H19N3O4S, CAS 606111-68-6
Ethanone, 1-(2,4-dimethoxyphenyl)-2-[[4-ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]-
CAS 606111-68-6C18H19N3O4S
1-(4-Bromophenyl)-2-[[5-(furan-2-yl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C17H14BrN3O2S, CAS 573950-34-2
1-(4-Bromophenyl)-2-[[5-(furan-2-yl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 573950-34-2C17H14BrN3O2S
1-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C17H14ClN3O2S, CAS 577960-08-8
1-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 577960-08-8C17H14ClN3O2S
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dihydroxyphenyl)ethanone chemical structure, C17H15N3O4S, CAS 578700-95-5
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dihydroxyphenyl)ethanone
CAS 578700-95-5C17H15N3O4S
2-[[4-Ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone chemical structure, C16H15N3O2S, CAS 603981-60-8
2-[[4-Ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone
CAS 603981-60-8C16H15N3O2S
1-(2,4-Dichlorophenyl)-2-[[5-(furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C15H11Cl2N3O2S, CAS 842116-03-4
1-(2,4-Dichlorophenyl)-2-[[5-(furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 842116-03-4C15H11Cl2N3O2S
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone chemical structure, C18H19N3O2S, CAS 606111-31-3
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone
CAS 606111-31-3C18H19N3O2S
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(3,4-dimethylphenyl)ethanone chemical structure, C20H23N3O2S, CAS 606111-39-1
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(3,4-dimethylphenyl)ethanone
CAS 606111-39-1C20H23N3O2S
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(2,4-dimethylphenyl)ethanone chemical structure, C20H23N3O2S, CAS 606111-47-1
2-[[4-Butyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(2,4-dimethylphenyl)ethanone
CAS 606111-47-1C20H23N3O2S
1-(3,4-Dimethylphenyl)-2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C18H19N3O2S, CAS 606111-55-1
1-(3,4-Dimethylphenyl)-2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 606111-55-1C18H19N3O2S