CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 25 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
11
With full pages
4
Scaffold SMILES

O=C(COc1ccccc1)NCC(c1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NCC(c1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-[2-(4-Methoxyphenyl)-2-piperidin-1-ylethyl]-2-phenoxyacetamide chemical structure, C22H28N2O3, CAS 851874-23-2
N-[2-(4-Methoxyphenyl)-2-piperidin-1-ylethyl]-2-phenoxyacetamide
CAS 851874-23-2C22H28N2O3
2-(3,5-Dimethylphenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide chemical structure, C24H32N2O3, CAS 874356-53-3
2-(3,5-Dimethylphenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide
CAS 874356-53-3C24H32N2O3
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-methylphenoxy)acetamide chemical structure, C22H27ClN2O2, CAS 898471-86-8
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-methylphenoxy)acetamide
CAS 898471-86-8C22H27ClN2O2
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-methoxyphenoxy)acetamide chemical structure, C22H27ClN2O3, CAS 898506-78-0
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-methoxyphenoxy)acetamide
CAS 898506-78-0C22H27ClN2O3
2-(4-Chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide chemical structure, C23H29ClN2O3, CAS 880787-37-1
2-(4-Chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide
CAS 880787-37-1C23H29ClN2O3
2-(4-Bromophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide chemical structure, C22H27BrN2O3, CAS 874129-47-2
2-(4-Bromophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide
CAS 874129-47-2C22H27BrN2O3
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(3,4-dimethylphenoxy)acetamide chemical structure, C23H29ClN2O2, CAS 898506-65-5
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(3,4-dimethylphenoxy)acetamide
CAS 898506-65-5C23H29ClN2O2
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-ethylphenoxy)acetamide chemical structure, C23H29ClN2O2, CAS 898506-96-2
N-[2-(4-Chlorophenyl)-2-(piperidin-1-yl)ethyl]-2-(4-ethylphenoxy)acetamide
CAS 898506-96-2C23H29ClN2O2
N-[2-(4-Methoxyphenyl)-2-(piperidin-1-yl)ethyl]-2-(2-methylphenoxy)acetamide chemical structure, C23H30N2O3, CAS 883697-70-9
N-[2-(4-Methoxyphenyl)-2-(piperidin-1-yl)ethyl]-2-(2-methylphenoxy)acetamide
CAS 883697-70-9C23H30N2O3
2-(4-Fluorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide chemical structure, C23H29FN2O3, CAS 883699-02-3
2-(4-Fluorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide
CAS 883699-02-3C23H29FN2O3
N-[2-(3,4-Dimethoxyphenyl)-2-(1-piperidinyl)ethyl]-2-phenoxyacetamide chemical structure, C23H30N2O4, CAS 1217035-59-0
N-[2-(3,4-Dimethoxyphenyl)-2-(1-piperidinyl)ethyl]-2-phenoxyacetamide
CAS 1217035-59-0C23H30N2O4