CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 26 atoms

135 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
135
With full pages
1
Scaffold SMILES

O=C(NCC(c1ccccc1)N1CCNCC1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC(c1ccccc1)N1CCNCC1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 135 chemicals

N1-(2,6-dimethylphenyl)-N2-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C23H29FN4O2, CAS 898432-16-1
N1-(2,6-dimethylphenyl)-N2-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898432-16-1C23H29FN4O2
N1-(3-chloro-2-methylphenyl)-N2-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C22H26ClFN4O2, CAS 898451-83-7
N1-(3-chloro-2-methylphenyl)-N2-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898451-83-7C22H26ClFN4O2
N'-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]-N-(2,4,6-trimethylphenyl)ethanediamide chemical structure, C24H31FN4O2, CAS 898432-25-2
N'-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]-N-(2,4,6-trimethylphenyl)ethanediamide
CAS 898432-25-2C24H31FN4O2
N1-(3-chloro-2-methylphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide chemical structure, C23H29ClN4O2, CAS 898452-25-0
N1-(3-chloro-2-methylphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide
CAS 898452-25-0C23H29ClN4O2
N1-mesityl-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide chemical structure, C25H34N4O2, CAS 898432-72-9
N1-mesityl-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide
CAS 898432-72-9C25H34N4O2
N'-(3-Methoxyphenyl)-N-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide chemical structure, C23H30N4O4, CAS 903305-10-2
N'-(3-Methoxyphenyl)-N-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide
CAS 903305-10-2C23H30N4O4
N1-(2,3-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H32N4O3, CAS 898432-06-9
N1-(2,3-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898432-06-9C24H32N4O3
N-(2,6-Dimethylphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide chemical structure, C24H32N4O3, CAS 903305-17-9
N-(2,6-Dimethylphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide
CAS 903305-17-9C24H32N4O3
N1-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(o-tolyl)oxalamide chemical structure, C23H30N4O3, CAS 898451-48-4
N1-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(o-tolyl)oxalamide
CAS 898451-48-4C23H30N4O3
N1-(3,4-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H32N4O3, CAS 898432-07-0
N1-(3,4-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898432-07-0C24H32N4O3
N1-(2,4-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H32N4O3, CAS 906150-78-5
N1-(2,4-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 906150-78-5C24H32N4O3
N1-(2,5-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H32N4O3, CAS 898451-50-8
N1-(2,5-dimethylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898451-50-8C24H32N4O3
N1-(2-methoxy-5-methylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H32N4O4, CAS 903305-27-1
N1-(2-methoxy-5-methylphenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 903305-27-1C24H32N4O4
N-(2-Ethylphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide chemical structure, C24H32N4O3, CAS 903305-38-4
N-(2-Ethylphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide
CAS 903305-38-4C24H32N4O3
N-(3,4-Dimethoxyphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide chemical structure, C24H32N4O5, CAS 903305-46-4
N-(3,4-Dimethoxyphenyl)-N'-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide
CAS 903305-46-4C24H32N4O5
N'-[2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]-N-(2,4,6-trimethylphenyl)ethanediamide chemical structure, C25H34N4O3, CAS 903305-52-2
N'-[2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]-N-(2,4,6-trimethylphenyl)ethanediamide
CAS 903305-52-2C25H34N4O3
N1-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(3-nitrophenyl)oxalamide chemical structure, C22H27N5O5, CAS 906150-89-8
N1-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(3-nitrophenyl)oxalamide
CAS 906150-89-8C22H27N5O5
N1-(4-(dimethylamino)phenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H33N5O3, CAS 903255-58-3
N1-(4-(dimethylamino)phenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 903255-58-3C24H33N5O3
N1-(3-acetamidophenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide chemical structure, C24H31N5O4, CAS 898432-10-5
N1-(3-acetamidophenyl)-N2-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)oxalamide
CAS 898432-10-5C24H31N5O4
N1-(2-methoxyphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide chemical structure, C23H30N4O3, CAS 898452-07-8
N1-(2-methoxyphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide
CAS 898452-07-8C23H30N4O3
N-(2-Methoxy-5-methylphenyl)-N'-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide chemical structure, C24H32N4O3, CAS 898432-60-5
N-(2-Methoxy-5-methylphenyl)-N'-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]ethanediamide
CAS 898432-60-5C24H32N4O3
N1-(3,4-dimethoxyphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide chemical structure, C24H32N4O4, CAS 898432-70-7
N1-(3,4-dimethoxyphenyl)-N2-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)oxalamide
CAS 898432-70-7C24H32N4O4
N-{2-[4-(Dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-N'-(4-methoxyphenyl)ethanediamide chemical structure, C24H33N5O3, CAS 941914-13-2
N-{2-[4-(Dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-N'-(4-methoxyphenyl)ethanediamide
CAS 941914-13-2C24H33N5O3
N1-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(2-methoxyphenyl)oxalamide chemical structure, C24H33N5O3, CAS 941995-37-5
N1-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-N2-(2-methoxyphenyl)oxalamide
CAS 941995-37-5C24H33N5O3