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Murcko scaffold

Ring system with 2 rings and 11 atoms

43 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
43
With full pages
8
Scaffold SMILES

C1=NCC(c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=NCC(c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

Aminorex chemical structure, C9H10N2O, CAS 2207-50-3
Aminorex
CAS 2207-50-3C9H10N2O
Clominorex chemical structure, C9H9ClN2O, CAS 3876-10-6
Clominorex
CAS 3876-10-6C9H9ClN2O
Fluminorex chemical structure, C10H9F3N2O, CAS 720-76-3
Fluminorex
CAS 720-76-3C10H9F3N2O
4,5-Dihydro-4-methyl-5-phenyl-2-oxazolamine chemical structure, C10H12N2O, CAS 3568-94-3
4,5-Dihydro-4-methyl-5-phenyl-2-oxazolamine
CAS 3568-94-3C10H12N2O
(2-Methyl-5-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol chemical structure, C11H13NO2
(2-Methyl-5-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol
C11H13NO2
4-Methylaminorex, (4S,5S)- chemical structure, C10H12N2O, CAS 27780-30-9
4-Methylaminorex, (4S,5S)-
CAS 27780-30-9C10H12N2O
5-(p-Tolyl)-4,5-dihydrooxazol-2-amine chemical structure, C10H12N2O, CAS 959249-62-8
5-(p-Tolyl)-4,5-dihydrooxazol-2-amine
CAS 959249-62-8C10H12N2O
(2-Ethyl-5-phenyl-4,5-dihydrooxazol-4-yl)methanol chemical structure, C12H15NO2, CAS 412308-66-8
(2-Ethyl-5-phenyl-4,5-dihydrooxazol-4-yl)methanol
CAS 412308-66-8C12H15NO2
Oxazole, 4,5-dihydro-4-(methoxymethyl)-2-methyl-5-phenyl-, (4S,5S)- chemical structure, C12H15NO2, CAS 52075-14-6
Oxazole, 4,5-dihydro-4-(methoxymethyl)-2-methyl-5-phenyl-, (4S,5S)-
CAS 52075-14-6C12H15NO2
(4S,5S)-(-)-2-Methyl-5-phenyl-2-oxazoline-4-methanol chemical structure, C11H13NO2, CAS 53732-41-5
(4S,5S)-(-)-2-Methyl-5-phenyl-2-oxazoline-4-methanol
CAS 53732-41-5C11H13NO2
Oxazolidine, 2-imino-4-methyl-5-phenyl-, hydrobromide (Z)-(+-)- chemical structure, C10H13BrN2O, CAS 75343-74-7
Oxazolidine, 2-imino-4-methyl-5-phenyl-, hydrobromide (Z)-(+-)-
CAS 75343-74-7C10H13BrN2O
4-Methylaminorex, (4R,5S)- chemical structure, C10H12N2O, CAS 27780-31-0
4-Methylaminorex, (4R,5S)-
CAS 27780-31-0C10H12N2O
(4S,5R)-4-Methylaminorex chemical structure, C10H12N2O, CAS 75493-87-7
(4S,5R)-4-Methylaminorex
CAS 75493-87-7C10H12N2O
Aminorex fumarate chemical structure, C13H14N2O5, CAS 13425-22-4
Aminorex fumarate
CAS 13425-22-4C13H14N2O5
C10H10NOSe chemical structure, C10H10NOSe, CAS 138715-28-3
C10H10NOSe
CAS 138715-28-3C10H10NOSe
(4R,5R)-2-(Dichloromethyl)-4,5-dihydro-5-(4-mesylphenyl)oxazol-4-ylmethanol chemical structure, C12H13Cl2NO4S, CAS 126813-11-4
(4R,5R)-2-(Dichloromethyl)-4,5-dihydro-5-(4-mesylphenyl)oxazol-4-ylmethanol
CAS 126813-11-4C12H13Cl2NO4S
C10H10NOSe chemical structure, C10H10NOSe, CAS 127399-16-0
C10H10NOSe
CAS 127399-16-0C10H10NOSe
(4S,5S)-(-)-2-Ethyl-5-phenyl-2-oxazoline-4-methanol chemical structure, C12H15NO2, CAS 51594-33-3
(4S,5S)-(-)-2-Ethyl-5-phenyl-2-oxazoline-4-methanol
CAS 51594-33-3C12H15NO2
4-Oxazoleacetonitrile, 4,5-dihydro-2-methyl-5-phenyl-, (4S,5S)- chemical structure, C12H12N2O, CAS 192803-70-6
4-Oxazoleacetonitrile, 4,5-dihydro-2-methyl-5-phenyl-, (4S,5S)-
CAS 192803-70-6C12H12N2O
(4R,5S)-4,5-Dihydro-4-methyl-5-phenyloxazole chemical structure, C10H11NO, CAS 136846-24-7
(4R,5S)-4,5-Dihydro-4-methyl-5-phenyloxazole
CAS 136846-24-7C10H11NO
Phenol, 3-(2-ethyl-4,5-dihydro-5-oxazolyl)- chemical structure, C11H13NO2, CAS 110193-51-6
Phenol, 3-(2-ethyl-4,5-dihydro-5-oxazolyl)-
CAS 110193-51-6C11H13NO2
(4R,5R)-4-Methylaminorex chemical structure, C10H12N2O, CAS 10189-63-6
(4R,5R)-4-Methylaminorex
CAS 10189-63-6C10H12N2O
5-Methoxy-2,4,4-trimethyl-5-phenyl-4,5-dihydro-1,3-oxazole--hydrogen chloride (1/1) chemical structure, C13H18ClNO2, CAS 56965-24-3
5-Methoxy-2,4,4-trimethyl-5-phenyl-4,5-dihydro-1,3-oxazole--hydrogen chloride (1/1)
CAS 56965-24-3C13H18ClNO2
2-tert-Butyl-5-methoxy-4,4-dimethyl-5-phenyl-4,5-dihydro-1,3-oxazole--hydrogen chloride (1/1) chemical structure, C16H24ClNO2, CAS 56965-26-5
2-tert-Butyl-5-methoxy-4,4-dimethyl-5-phenyl-4,5-dihydro-1,3-oxazole--hydrogen chloride (1/1)
CAS 56965-26-5C16H24ClNO2