CompoundList
Sign in
Murcko scaffold

N-Benzyl-6-imino-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide scaffold

34 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
34
Chemicals
34
With full pages
4
Scaffold SMILES

N=c1c(C(=O)NCc2ccccc2)cc2c(=O)n3ccccc3nc2n1CCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-6-imino-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide page
Murcko scaffold N=c1c(C(=O)NCc2ccccc2)cc2c(=O)n3ccccc3nc2n1CCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

N-Benzyl-6-imino-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C27H23N5O2, CAS 615273-58-0
N-Benzyl-6-imino-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
CAS 615273-58-0C27H23N5O2
N-(2-Chlorobenzyl)-1-(3,4-dimethoxyphenethyl)-2-imino-10-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H28ClN5O4, CAS 713088-77-8
N-(2-Chlorobenzyl)-1-(3,4-dimethoxyphenethyl)-2-imino-10-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 713088-77-8C30H28ClN5O4
N-Benzyl-2-imino-10-methyl-5-oxo-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C28H25N5O2, CAS 608491-83-4
N-Benzyl-2-imino-10-methyl-5-oxo-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 608491-83-4C28H25N5O2
2-Imino-5-oxo-N-(1-phenylethyl)-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C28H25N5O2, CAS 608494-65-1
2-Imino-5-oxo-N-(1-phenylethyl)-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 608494-65-1C28H25N5O2
N-Benzyl-2-imino-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O3, CAS 573936-83-1
N-Benzyl-2-imino-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 573936-83-1C29H27N5O3
N-(2-Chlorobenzyl)-2-imino-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H26ClN5O3, CAS 877646-45-2
N-(2-Chlorobenzyl)-2-imino-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 877646-45-2C29H26ClN5O3
N-(2-Chlorobenzyl)-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H26ClN5O4, CAS 847339-11-1
N-(2-Chlorobenzyl)-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 847339-11-1C29H26ClN5O4
2-Imino-1-[2-(4-methoxyphenyl)ethyl]-5-oxo-N-(1-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O3, CAS 858753-75-0
2-Imino-1-[2-(4-methoxyphenyl)ethyl]-5-oxo-N-(1-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 858753-75-0C29H27N5O3
2-Imino-N-(4-methoxybenzyl)-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H29N5O4, CAS 850245-13-5
2-Imino-N-(4-methoxybenzyl)-1-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 850245-13-5C30H29N5O4
2-Imino-1-[2-(4-methoxyphenyl)ethyl]-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O3, CAS 573707-94-5
2-Imino-1-[2-(4-methoxyphenyl)ethyl]-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 573707-94-5C29H27N5O3
N-[(4-Fluorophenyl)methyl]-6-imino-11-methyl-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C28H24FN5O2, CAS 844835-80-9
N-[(4-Fluorophenyl)methyl]-6-imino-11-methyl-2-oxo-7-(2-phenylethyl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
CAS 844835-80-9C28H24FN5O2
N-Benzyl-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O4, CAS 841206-76-6
N-Benzyl-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 841206-76-6C29H27N5O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-5-oxo-N-(1-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H29N5O4, CAS 893695-36-8
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-5-oxo-N-(1-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 893695-36-8C30H29N5O4
2-Imino-N-(4-methoxybenzyl)-1-[2-(4-methoxyphenyl)ethyl]-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O4, CAS 859137-50-1
2-Imino-N-(4-methoxybenzyl)-1-[2-(4-methoxyphenyl)ethyl]-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 859137-50-1C29H27N5O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methoxybenzyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C31H31N5O5, CAS 858761-52-1
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methoxybenzyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 858761-52-1C31H31N5O5
2-Imino-10-methyl-N-(4-methylbenzyl)-5-oxo-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H27N5O2, CAS 636989-28-1
2-Imino-10-methyl-N-(4-methylbenzyl)-5-oxo-1-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 636989-28-1C29H27N5O2
N-Benzyl-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H29N5O4, CAS 840515-69-7
N-Benzyl-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 840515-69-7C30H29N5O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H29N5O4, CAS 578736-86-4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 578736-86-4C30H29N5O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-fluorobenzyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H28FN5O4, CAS 877777-07-6
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-fluorobenzyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 877777-07-6C30H28FN5O4
N~3~-(2-chlorobenzyl)-2-imino-10-methyl-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C28H24ClN5O2, CAS 844648-65-3
N~3~-(2-chlorobenzyl)-2-imino-10-methyl-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 844648-65-3C28H24ClN5O2
N~3~-(4-fluorobenzyl)-2-imino-1-(4-methoxyphenethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C28H24FN5O3, CAS 848756-43-4
N~3~-(4-fluorobenzyl)-2-imino-1-(4-methoxyphenethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 848756-43-4C28H24FN5O3
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-10-methyl-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C31H31N5O4, CAS 848688-47-1
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-10-methyl-N-(4-methylbenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 848688-47-1C31H31N5O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methoxybenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C30H29N5O5, CAS 858751-32-3
1-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-N-(4-methoxybenzyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 858751-32-3C30H29N5O5
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-fluorobenzyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C29H26FN5O4, CAS 848746-55-4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-fluorobenzyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 848746-55-4C29H26FN5O4