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Murcko scaffold

Ring system with 4 rings and 21 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
12
With full pages
3
Scaffold SMILES

O=C1C=CC(OC=C2C(=O)OC3c4ccccc4CC23)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC(OC=C2C(=O)OC3c4ccccc4CC23)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one chemical structure, C17H14O5
3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one
C17H14O5
GR 24 chemical structure, C17H14O5
GR 24
C17H14O5
(3Z)-3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one chemical structure, C17H14O5, CAS 80286-95-9
(3Z)-3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one
CAS 80286-95-9C17H14O5
(3E,3aS,8bR)-3-((((2R)-2,5-Dihydro-4-methyl-5-oxo-2-furanyl)oxy)methylene)-3,3a,4,8b-tetrahydro-2H-indeno(1,2-b)furan-2-one chemical structure, C17H14O5, CAS 188062-51-3
(3E,3aS,8bR)-3-((((2R)-2,5-Dihydro-4-methyl-5-oxo-2-furanyl)oxy)methylene)-3,3a,4,8b-tetrahydro-2H-indeno(1,2-b)furan-2-one
CAS 188062-51-3C17H14O5
(3E,3aR,8bS)-3-({[(2r)-4-Methyl-5-Oxo-2,5-Dihydrofuran-2-Yl]oxy}methylidene)-3,3a,4,8b-Tetrahydro-2H-Indeno[1,2-B]furan-2-One chemical structure, C17H14O5, CAS 76974-79-3
(3E,3aR,8bS)-3-({[(2r)-4-Methyl-5-Oxo-2,5-Dihydrofuran-2-Yl]oxy}methylidene)-3,3a,4,8b-Tetrahydro-2H-Indeno[1,2-B]furan-2-One
CAS 76974-79-3C17H14O5
Solanacol chemical structure, C19H18O6, CAS 953389-72-5
Solanacol
CAS 953389-72-5C19H18O6
(+)-Strigolactone GR24 chemical structure, C17H14O5, CAS 151716-22-2
(+)-Strigolactone GR24
CAS 151716-22-2C17H14O5
epi-(+)-Strigolactone GR24 chemical structure, C17H14O5, CAS 151716-23-3
epi-(+)-Strigolactone GR24
CAS 151716-23-3C17H14O5
(3aR,8bS)-3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one chemical structure, C17H14O5
(3aR,8bS)-3-[(4-Methyl-5-oxo-2H-furan-2-yl)oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one
C17H14O5
rac-GR24 chemical structure, C17H14O5
rac-GR24
C17H14O5
Autophagy-IN-1 chemical structure, C23H25NO7, CAS 3031485-19-2
Autophagy-IN-1
CAS 3031485-19-2C23H25NO7
(3Z,3aS,8bR)-3-[[(2S)-4-Methyl-5-oxo-2H-furan-2-yl]oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one chemical structure, C17H14O5, CAS 188062-52-4
(3Z,3aS,8bR)-3-[[(2S)-4-Methyl-5-oxo-2H-furan-2-yl]oxymethylidene]-4,8b-dihydro-3aH-indeno[1,2-b]furan-2-one
CAS 188062-52-4C17H14O5