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Murcko scaffold

Ring system with 4 rings and 23 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
15
With full pages
3
Scaffold SMILES

c1ccc(CNc2ccc3ncc(-c4ccccc4)n3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNc2ccc3ncc(-c4ccccc4)n3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

4-(6-(3-Chlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide chemical structure, C24H25ClN6O, CAS 1010441-65-2
4-(6-(3-Chlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide
CAS 1010441-65-2C24H25ClN6O
IRAK inhibitor 3 chemical structure, C21H21N5O4S, CAS 1012343-93-9
IRAK inhibitor 3
CAS 1012343-93-9C21H21N5O4S
4-((3-(4-(Trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzene-sulfonamide chemical structure, C20H16F3N5O3S, CAS 1012343-94-0
4-((3-(4-(Trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzene-sulfonamide
CAS 1012343-94-0C20H16F3N5O3S
4-((3-(4-(Hydroxymethyl)phenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzenesulfonamide chemical structure, C20H19N5O3S, CAS 1012343-96-2
4-((3-(4-(Hydroxymethyl)phenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzenesulfonamide
CAS 1012343-96-2C20H19N5O3S
4-((3-(3-Formylphenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzenesulfonamide chemical structure, C20H17N5O3S, CAS 1012344-02-3
4-((3-(3-Formylphenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)benzenesulfonamide
CAS 1012344-02-3C20H17N5O3S
3-(4-Aminophenyl)-N-(4-methoxybenzyl)imidazo[1,2-b]pyridazin-6-amine chemical structure, C20H19N5O, CAS 1012344-53-4
3-(4-Aminophenyl)-N-(4-methoxybenzyl)imidazo[1,2-b]pyridazin-6-amine
CAS 1012344-53-4C20H19N5O
3-(6-(3,4,5-Trimethoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol chemical structure, C22H22N4O4, CAS 1012343-99-5
3-(6-(3,4,5-Trimethoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol
CAS 1012343-99-5C22H22N4O4
N-Benzyl-3-(4-fluorophenyl)imidazo[1,2-b]pyridazin-6-amine chemical structure, C19H15FN4, CAS 1012345-48-0
N-Benzyl-3-(4-fluorophenyl)imidazo[1,2-b]pyridazin-6-amine
CAS 1012345-48-0C19H15FN4
Taletrectinib chemical structure, C23H24FN5O, CAS 1505514-27-1
Taletrectinib
CAS 1505514-27-1C23H24FN5O
3-[4-[(2R)-2-Aminopropoxy]phenyl]-N-[(1R)-1-(3-fluorophenyl)ethyl]imidazo[1,2-b]pyridazin-6-amine, hexanedioic acid chemical structure, C29H34FN5O5, CAS 1505515-69-4
3-[4-[(2R)-2-Aminopropoxy]phenyl]-N-[(1R)-1-(3-fluorophenyl)ethyl]imidazo[1,2-b]pyridazin-6-amine, hexanedioic acid
CAS 1505515-69-4C29H34FN5O5
N-Benzyl-3-(2-methoxy-4-nitrophenyl)-N-methylimidazo[1,2-b]pyridazin-6-amine chemical structure, C21H19N5O3, CAS 1644250-36-1
N-Benzyl-3-(2-methoxy-4-nitrophenyl)-N-methylimidazo[1,2-b]pyridazin-6-amine
CAS 1644250-36-1C21H19N5O3
2-Methoxy-4-(6-(3,4,5-trimethoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol chemical structure, C23H24N4O5, CAS 1012344-39-6
2-Methoxy-4-(6-(3,4,5-trimethoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol
CAS 1012344-39-6C23H24N4O5
2-Methoxy-4-(6-(4-methoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol chemical structure, C21H20N4O3, CAS 1012344-51-2
2-Methoxy-4-(6-(4-methoxybenzylamino)imidazo[1,2-b]pyridazin-3-yl)phenol
CAS 1012344-51-2C21H20N4O3
4-(6-(3,4-Dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-2-methoxyphenol chemical structure, C20H16Cl2N4O2, CAS 1012344-80-7
4-(6-(3,4-Dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-2-methoxyphenol
CAS 1012344-80-7C20H16Cl2N4O2
4-(6-(2,4-Dimethylbenzylamino)imidazo[1,2-b]pyridazin-3-yl)-2-methoxyphenol chemical structure, C22H22N4O2, CAS 1012344-81-8
4-(6-(2,4-Dimethylbenzylamino)imidazo[1,2-b]pyridazin-3-yl)-2-methoxyphenol
CAS 1012344-81-8C22H22N4O2