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Murcko scaffold

Ring system with 3 rings and 26 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
11
With full pages
1
Scaffold SMILES

O=C(CSc1nnc(CCCOc2ccccc2)[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(CCCOc2ccccc2)[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methyl-5-nitrophenyl)acetamide chemical structure, C21H21Cl2N5O4S, CAS 708250-65-1
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methyl-5-nitrophenyl)acetamide
CAS 708250-65-1C21H21Cl2N5O4S
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-(2-ethyl-6-methylphenyl)acetamide chemical structure, C23H26Cl2N4O2S, CAS 708250-78-6
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-(2-ethyl-6-methylphenyl)acetamide
CAS 708250-78-6C23H26Cl2N4O2S
N-(3-Chloro-4-fluorophenyl)-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H18Cl3FN4O2S, CAS 708292-03-9
N-(3-Chloro-4-fluorophenyl)-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 708292-03-9C20H18Cl3FN4O2S
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-fluoro-2-methylphenyl)acetamide chemical structure, C22H23Cl2FN4O2S, CAS 767324-01-6
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-fluoro-2-methylphenyl)acetamide
CAS 767324-01-6C22H23Cl2FN4O2S
N-(2-Bromo-4,5-dimethylphenyl)-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C22H23BrCl2N4O2S, CAS 708285-02-3
N-(2-Bromo-4,5-dimethylphenyl)-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 708285-02-3C22H23BrCl2N4O2S
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C21H18Cl3F3N4O2S, CAS 708994-00-7
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[[5-[3-(2,4-dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 708994-00-7C21H18Cl3F3N4O2S
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methylsulfanylphenyl)acetamide chemical structure, C21H22Cl2N4O2S2, CAS 708995-25-9
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methylsulfanylphenyl)acetamide
CAS 708995-25-9C21H22Cl2N4O2S2
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-fluorophenyl)acetamide chemical structure, C20H19Cl2FN4O2S, CAS 767325-90-6
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-fluorophenyl)acetamide
CAS 767325-90-6C20H19Cl2FN4O2S
Methyl 2-{[({5-[3-(2,4-dichlorophenoxy)propyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}sulfanyl)acetyl]amino}benzoate chemical structure, C24H24Cl2N4O4S, CAS 708252-30-6
Methyl 2-{[({5-[3-(2,4-dichlorophenoxy)propyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}sulfanyl)acetyl]amino}benzoate
CAS 708252-30-6C24H24Cl2N4O4S
3-{[({5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetyl]amino}benzoic acid chemical structure, C21H20Cl2N4O4S, CAS 878987-16-7
3-{[({5-[3-(2,4-Dichlorophenoxy)propyl]-4-methyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetyl]amino}benzoic acid
CAS 878987-16-7C21H20Cl2N4O4S
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-nitrophenyl)acetamide chemical structure, C22H21Cl2N5O4S, CAS 708999-80-8
2-[[5-[3-(2,4-Dichlorophenoxy)propyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-nitrophenyl)acetamide
CAS 708999-80-8C22H21Cl2N5O4S