Murcko scaffold
Ring system with 5 rings and 19 atoms
23 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 19
- Chemicals
- 23
- With full pages
- 1
Scaffold SMILES
O=C1C=C2CCC3C4CCCC4CC4OC43C2CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
Pregn-4-ene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9beta,11beta)-
CAS 10072-97-6C21H28O5
Androst-4-en-3-one, 9,11-epoxy-17-hydroxy-17-methyl-, (11alpha,17beta)-
CAS 71423-83-1C20H28O3
9,11-Epoxy-17-hydroxy-17-methylandrost-4-en-3-one, (9beta,11beta,17beta)-
CAS 1042-33-7C20H28O3
17-Hydroxy-3,20-dioxo-9,11-epoxypregn-4-en-21-yl acetate
C23H30O6
17-Hydroxy-2,17-dimethyl-9,11-epoxyandrost-4-en-3-one
CAS 80651-69-0C21H30O3
SC-70303 free acid
CAS 579484-30-3C24H32O7
SC-70303
CAS 95716-98-6C24H31KO7
9,11alpha-Epoxy-17-hydroxypregn-4-ene-3,20-dione 17-acetate
CAS 94425-51-1C23H30O5
Pregn-4-ene-3,20-dione,21-(acetyloxy)-9,11-epoxy-17-hydroxy-, (9b,11b)-
C23H30O6
3,20-Dioxo-9,11-epoxypregn-4-ene-17,21-diyl diacetate
CAS 85707-50-2C25H32O7
![(14-Acetyl-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-14-yl) acetate chemical structure, C23H30O5](/s/UHRIXJLDCNOZKI-UHFFFAOYSA-N.svg)
(14-Acetyl-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-14-yl) acetate
C23H30O5
9beta,11beta-Epoxy-17,21-dihydroxy-16beta-methyl-pregn-4-ene-3,20-dione
CAS 114488-14-1C22H30O5
Budesonide impurity 114
CAS 18769-18-1C24H32O6
ZH29Mqq4EB
CAS 4383-30-6C23H30O6
![(1R,2S,9R,14R,15S,17R)-14-(2-Carboxyethyl)-14-hydroxy-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-9-carboxylic acid chemical structure, C23H30O7, CAS 1621954-05-9](/s/XARCRMIYHJORRZ-XCWHUGCHSA-N.svg)
(1R,2S,9R,14R,15S,17R)-14-(2-Carboxyethyl)-14-hydroxy-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-9-carboxylic acid
CAS 1621954-05-9C23H30O7
Epoxyhydrocortisone acetate
C23H30O6
Dexamethasone impurity 147
CAS 34542-58-0C24H32O6
![(2S,8S,10S,11S,14R,15S)-14-[2-(Acetyloxy)acetyl]-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.0,.0,.0,octadec-6-en-14-yl butanoate chemical structure, C27H35FO7, CAS 51227-83-9](/s/PPMLNXRIYTZUBG-RVHYNSEKSA-N.svg)
(2S,8S,10S,11S,14R,15S)-14-[2-(Acetyloxy)acetyl]-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.0,.0,.0,octadec-6-en-14-yl butanoate
CAS 51227-83-9C27H35FO7
![[(2S,8S,11S,14R,15S)-14-(2-Acetyloxyacetyl)-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-14-yl] butanoate chemical structure, C27H35FO7](/s/PPMLNXRIYTZUBG-LMHIXRLKSA-N.svg)
[(2S,8S,11S,14R,15S)-14-(2-Acetyloxyacetyl)-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-14-yl] butanoate
C27H35FO7
9,11alpha-Epoxy-17-hydroxypregn-4-ene-3,20-dione 17-acetate
C23H30O5
![(2S,8S,10S,11S,14R,15S)-14-[2-(Acetyloxy)acetyl]-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.0(1),(1).0(2),.0(1)(1),(1)]octadec-6-en-14-yl butanoate chemical structure, C27H35FO7](/s/PPMLNXRIYTZUBG-ZJLOMJDHSA-N.svg)
(2S,8S,10S,11S,14R,15S)-14-[2-(Acetyloxy)acetyl]-8-fluoro-2,15-dimethyl-5-oxo-18-oxapentacyclo[8.8.0.0(1),(1).0(2),.0(1)(1),(1)]octadec-6-en-14-yl butanoate
C27H35FO7
Penicildione B
CAS 2770242-92-5C22H30O5
Eplerenone EP impurity F sodium salt
CAS 3070439-21-0C24H31NaO7
Related scaffolds
Same ring framework with different atoms or bond orders
