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Murcko scaffold

Ring system with 4 rings and 26 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
18
With full pages
6
Scaffold SMILES

O=C(Nc1sccc1C(c1ccccc1)N1CCOCC1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1sccc1C(c1ccccc1)N1CCOCC1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

N-[3-[(2-Fluorophenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide chemical structure, C22H23FN2O3S, CAS 618406-75-0
N-[3-[(2-Fluorophenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide
CAS 618406-75-0C22H23FN2O3S
N-(4,5-Dimethyl-3-((4-(methylthio)phenyl)(morpholino)methyl)thiophen-2-yl)furan-2-carboxamide chemical structure, C23H26N2O3S2, CAS 618405-65-5
N-(4,5-Dimethyl-3-((4-(methylthio)phenyl)(morpholino)methyl)thiophen-2-yl)furan-2-carboxamide
CAS 618405-65-5C23H26N2O3S2
N-{3-[(4-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C22H23FN2O3S, CAS 618405-79-1
N-{3-[(4-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618405-79-1C22H23FN2O3S
N-{3-[(3-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C22H23FN2O3S, CAS 618406-37-4
N-{3-[(3-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618406-37-4C22H23FN2O3S
N-(4,5-Dimethyl-3-{4-morpholinyl[4-(trifluoromethyl)phenyl]methyl}-2-thienyl)-2-furamide chemical structure, C23H23F3N2O3S, CAS 618405-98-4
N-(4,5-Dimethyl-3-{4-morpholinyl[4-(trifluoromethyl)phenyl]methyl}-2-thienyl)-2-furamide
CAS 618405-98-4C23H23F3N2O3S
N-{3-[(3-Chlorophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}-2-furamide chemical structure, C22H23ClN2O3S, CAS 618406-45-4
N-{3-[(3-Chlorophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}-2-furamide
CAS 618406-45-4C22H23ClN2O3S
N-{3-[(4-Methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C23H26N2O4S, CAS 618405-43-9
N-{3-[(4-Methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618405-43-9C23H26N2O4S
N-{3-[(3-Bromophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}-2-furamide chemical structure, C22H23BrN2O3S, CAS 618406-53-4
N-{3-[(3-Bromophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}-2-furamide
CAS 618406-53-4C22H23BrN2O3S
N-[3-[[4-(Diethylamino)phenyl]-4-morpholinylmethyl]-4,5-dimethyl-2-thienyl]-2-furancarboxamide chemical structure, C26H33N3O3S, CAS 618406-18-1
N-[3-[[4-(Diethylamino)phenyl]-4-morpholinylmethyl]-4,5-dimethyl-2-thienyl]-2-furancarboxamide
CAS 618406-18-1C26H33N3O3S
N-(4,5-Dimethyl-3-(morpholino(p-tolyl)methyl)thiophen-2-yl)furan-2-carboxamide chemical structure, C23H26N2O3S, CAS 618405-35-9
N-(4,5-Dimethyl-3-(morpholino(p-tolyl)methyl)thiophen-2-yl)furan-2-carboxamide
CAS 618405-35-9C23H26N2O3S
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C24H28N2O4S, CAS 618405-51-9
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618405-51-9C24H28N2O4S
N-[4,5-Dimethyl-3-[morpholin-4-yl-(4-propan-2-ylphenyl)methyl]thiophen-2-yl]furan-2-carboxamide chemical structure, C25H30N2O3S, CAS 618406-05-6
N-[4,5-Dimethyl-3-[morpholin-4-yl-(4-propan-2-ylphenyl)methyl]thiophen-2-yl]furan-2-carboxamide
CAS 618406-05-6C25H30N2O3S
N-[3-[(3-Methoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide chemical structure, C23H26N2O4S, CAS 618406-30-7
N-[3-[(3-Methoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide
CAS 618406-30-7C23H26N2O4S
N-{3-[(2-Methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C23H26N2O4S, CAS 618406-68-1
N-{3-[(2-Methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618406-68-1C23H26N2O4S
N-{3-[(2-Chlorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide chemical structure, C22H23ClN2O3S, CAS 618406-82-9
N-{3-[(2-Chlorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}furan-2-carboxamide
CAS 618406-82-9C22H23ClN2O3S
N-[3-[(3,4-Dimethoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide chemical structure, C24H28N2O5S, CAS 618407-04-8
N-[3-[(3,4-Dimethoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide
CAS 618407-04-8C24H28N2O5S
N-[3-[(2,5-Dimethoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide chemical structure, C24H28N2O5S, CAS 618407-34-4
N-[3-[(2,5-Dimethoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]furan-2-carboxamide
CAS 618407-34-4C24H28N2O5S
N-{4,5-Dimethyl-3-[morpholin-4-yl(3,4,5-trimethoxyphenyl)methyl]thiophen-2-yl}furan-2-carboxamide chemical structure, C25H30N2O6S, CAS 618407-48-0
N-{4,5-Dimethyl-3-[morpholin-4-yl(3,4,5-trimethoxyphenyl)methyl]thiophen-2-yl}furan-2-carboxamide
CAS 618407-48-0C25H30N2O6S