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Murcko scaffold

Ring system with 4 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
2
Scaffold SMILES

O=C1NC(=O)c2cc(-c3nc4ccccc4c(=O)o3)ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)c2cc(-c3nc4ccccc4c(=O)o3)ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

5-(6-Chloro-4-oxo-4H-3,1-benzoxazin-2-yl)-2-methyl-1H-isoindole-1,3(2H)-dione chemical structure, C17H9ClN2O4, CAS 519147-50-3
5-(6-Chloro-4-oxo-4H-3,1-benzoxazin-2-yl)-2-methyl-1H-isoindole-1,3(2H)-dione
CAS 519147-50-3C17H9ClN2O4
2-(3-Methylbutyl)-5-(4-oxo-3,1-benzoxazin-2-yl)isoindole-1,3-dione chemical structure, C21H18N2O4, CAS 354120-42-6
2-(3-Methylbutyl)-5-(4-oxo-3,1-benzoxazin-2-yl)isoindole-1,3-dione
CAS 354120-42-6C21H18N2O4
5-(6-Bromo-4-oxo-3,1-benzoxazin-2-yl)-2-(3-methylbutyl)isoindole-1,3-dione chemical structure, C21H17BrN2O4, CAS 354120-43-7
5-(6-Bromo-4-oxo-3,1-benzoxazin-2-yl)-2-(3-methylbutyl)isoindole-1,3-dione
CAS 354120-43-7C21H17BrN2O4
5-(7-Chloro-4-oxo-4H-3,1-benzoxazin-2-yl)-2-isopentyl-1H-isoindole-1,3(2H)-dione chemical structure, C21H17ClN2O4, CAS 354120-44-8
5-(7-Chloro-4-oxo-4H-3,1-benzoxazin-2-yl)-2-isopentyl-1H-isoindole-1,3(2H)-dione
CAS 354120-44-8C21H17ClN2O4
3-[1,3-Dioxo-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1,3-dihydro-2H-isoindol-2-yl]propanoic acid chemical structure, C19H12N2O6, CAS 305360-43-4
3-[1,3-Dioxo-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1,3-dihydro-2H-isoindol-2-yl]propanoic acid
CAS 305360-43-4C19H12N2O6
5-(6-Bromo-4-oxo-3,1-benzoxazin-2-yl)-2-methylisoindole-1,3-dione chemical structure, C17H9BrN2O4, CAS 500262-00-0
5-(6-Bromo-4-oxo-3,1-benzoxazin-2-yl)-2-methylisoindole-1,3-dione
CAS 500262-00-0C17H9BrN2O4
2-[2-(3-Methylbutyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-4H-3,1-benzoxazin-6-yl acetate chemical structure, C23H20N2O6, CAS 354120-45-9
2-[2-(3-Methylbutyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-4H-3,1-benzoxazin-6-yl acetate
CAS 354120-45-9C23H20N2O6
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-(2-methylpropyl)isoindole-1,3-dione chemical structure, C22H20N2O6, CAS 500263-71-8
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-(2-methylpropyl)isoindole-1,3-dione
CAS 500263-71-8C22H20N2O6
5-(7-Chloro-4-oxo-3,1-benzoxazin-2-yl)-2-ethylisoindole-1,3-dione chemical structure, C18H11ClN2O4, CAS 518021-77-7
5-(7-Chloro-4-oxo-3,1-benzoxazin-2-yl)-2-ethylisoindole-1,3-dione
CAS 518021-77-7C18H11ClN2O4
2-(1,3-Dioxo-2-propyl-2,3-dihydro-1H-isoindol-5-yl)-4-oxo-4H-3,1-benzoxazin-6-yl acetate chemical structure, C21H16N2O6, CAS 667409-99-6
2-(1,3-Dioxo-2-propyl-2,3-dihydro-1H-isoindol-5-yl)-4-oxo-4H-3,1-benzoxazin-6-yl acetate
CAS 667409-99-6C21H16N2O6
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-propylisoindole-1,3-dione chemical structure, C21H18N2O6, CAS 693813-09-1
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-propylisoindole-1,3-dione
CAS 693813-09-1C21H18N2O6
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-(3-methylbutyl)isoindole-1,3-dione chemical structure, C23H22N2O6, CAS 370841-33-1
5-(6,7-Dimethoxy-4-oxo-3,1-benzoxazin-2-yl)-2-(3-methylbutyl)isoindole-1,3-dione
CAS 370841-33-1C23H22N2O6
2-[1,3-Dioxo-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1,3-dihydro-2H-isoindol-2-yl]ethyl acetate chemical structure, C20H14N2O6, CAS 371133-65-2
2-[1,3-Dioxo-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1,3-dihydro-2H-isoindol-2-yl]ethyl acetate
CAS 371133-65-2C20H14N2O6
2-Methyl-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1H-isoindole-1,3(2H)-dione chemical structure, C17H10N2O4, CAS 305360-45-6
2-Methyl-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1H-isoindole-1,3(2H)-dione
CAS 305360-45-6C17H10N2O4