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Murcko scaffold

Ring system with 2 rings and 15 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
19
With full pages
4
Scaffold SMILES

O=C1NCCCC1=NNc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCCCC1=NNc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

3-[2-(4-Fluorophenyl)hydrazin-1-ylidene]piperidin-2-one chemical structure, C11H12FN3O
3-[2-(4-Fluorophenyl)hydrazin-1-ylidene]piperidin-2-one
C11H12FN3O
2,3-Piperidinedione, 3-[2-(4-methoxy-2-nitrophenyl)hydrazone] chemical structure, C12H14N4O4, CAS 94850-48-3
2,3-Piperidinedione, 3-[2-(4-methoxy-2-nitrophenyl)hydrazone]
CAS 94850-48-3C12H14N4O4
(3Z)-3-[2-(2-Bromo-4-methylphenyl)hydrazinylidene]piperidin-2-one chemical structure, C12H14BrN3O, CAS 94850-63-2
(3Z)-3-[2-(2-Bromo-4-methylphenyl)hydrazinylidene]piperidin-2-one
CAS 94850-63-2C12H14BrN3O
(3Z)-3-[(4-Methylphenyl)hydrazinylidene]piperidin-2-one chemical structure, C12H15N3O, CAS 3464-81-1
(3Z)-3-[(4-Methylphenyl)hydrazinylidene]piperidin-2-one
CAS 3464-81-1C12H15N3O
(3Z)-3-[2-(4-Fluorophenyl)hydrazin-1-ylidene]piperidin-2-one chemical structure, C11H12FN3O, CAS 1086239-84-0
(3Z)-3-[2-(4-Fluorophenyl)hydrazin-1-ylidene]piperidin-2-one
CAS 1086239-84-0C11H12FN3O
(3E)-3-[(2-Methylphenyl)hydrazinylidene]piperidin-2-one chemical structure, C12H15N3O, CAS 14490-03-0
(3E)-3-[(2-Methylphenyl)hydrazinylidene]piperidin-2-one
CAS 14490-03-0C12H15N3O
(3E)-3-[(4-Fluorophenyl)hydrazinylidene]piperidin-2-one chemical structure, C11H12FN3O
(3E)-3-[(4-Fluorophenyl)hydrazinylidene]piperidin-2-one
C11H12FN3O
(3E)-3-[(2,5-Dimethoxyphenyl)hydrazinylidene]piperidin-2-one chemical structure, C13H17N3O3, CAS 94850-50-7
(3E)-3-[(2,5-Dimethoxyphenyl)hydrazinylidene]piperidin-2-one
CAS 94850-50-7C13H17N3O3
(3E)-3-[(4-Bromophenyl)hydrazinylidene]piperidin-2-one chemical structure, C11H12BrN3O, CAS 145489-89-0
(3E)-3-[(4-Bromophenyl)hydrazinylidene]piperidin-2-one
CAS 145489-89-0C11H12BrN3O
(3E)-3-[2-(4-Methyl-2-nitrophenyl)hydrazinylidene]piperidin-2-one chemical structure, C12H14N4O3, CAS 94850-47-2
(3E)-3-[2-(4-Methyl-2-nitrophenyl)hydrazinylidene]piperidin-2-one
CAS 94850-47-2C12H14N4O3
(3Z)-3-(Phenylhydrazinylidene)piperidin-2-one chemical structure, C11H13N3O, CAS 57073-81-1
(3Z)-3-(Phenylhydrazinylidene)piperidin-2-one
CAS 57073-81-1C11H13N3O
Acetic acid, 2-(o-((2-oxo-3-piperidinylidene)hydrazinyl)phenyl)- chemical structure, C13H15N3O3, CAS 66953-62-6
Acetic acid, 2-(o-((2-oxo-3-piperidinylidene)hydrazinyl)phenyl)-
CAS 66953-62-6C13H15N3O3
2,3-Piperidinedione, 4-methyl-, 3-[(4-methoxyphenyl)hydrazone], (Z)- chemical structure, C13H17N3O2, CAS 139591-09-6
2,3-Piperidinedione, 4-methyl-, 3-[(4-methoxyphenyl)hydrazone], (Z)-
CAS 139591-09-6C13H17N3O2
(E)-Ethyl 4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate chemical structure, C14H17N3O3
(E)-Ethyl 4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate
C14H17N3O3
TV3X42Unr2 chemical structure, C12H15N3O2, CAS 104742-98-5
TV3X42Unr2
CAS 104742-98-5C12H15N3O2
Ethyl 4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate chemical structure, C14H17N3O3, CAS 916522-66-2
Ethyl 4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate
CAS 916522-66-2C14H17N3O3
3-[2-(3,5-Dimethoxyphenyl)hydrazinylidene]piperidin-2-one chemical structure, C13H17N3O3, CAS 94850-51-8
3-[2-(3,5-Dimethoxyphenyl)hydrazinylidene]piperidin-2-one
CAS 94850-51-8C13H17N3O3
3-{2-[2-(Trifluoromethyl)phenyl]hydrazinylidene}piperidin-2-one chemical structure, C12H12F3N3O, CAS 111492-70-7
3-{2-[2-(Trifluoromethyl)phenyl]hydrazinylidene}piperidin-2-one
CAS 111492-70-7C12H12F3N3O
Ethyl4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate chemical structure, C14H17N3O3
Ethyl4-(2-(2-oxopiperidin-3-ylidene)hydrazinyl)benzoate
C14H17N3O3