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Murcko scaffold

Ring system with 3 rings and 20 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
18
With full pages
7
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cnc2ccccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cnc2ccccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

N'-[(2,5-Dimethoxyphenyl)methylidene]-2,7-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C19H20N4O3
N'-[(2,5-Dimethoxyphenyl)methylidene]-2,7-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide
C19H20N4O3
N-(Benzylideneamino)-2,8-dimethylimidazo[1,2-a]pyridine-3-carboxamide chemical structure, C17H16N4O, CAS 4743-19-5
N-(Benzylideneamino)-2,8-dimethylimidazo[1,2-a]pyridine-3-carboxamide
CAS 4743-19-5C17H16N4O
6-Chloro-2-methyl-N-[(Z)-(3,4,5-trimethoxyphenyl)methylideneamino]imidazo[1,2-a]pyridine-3-carboxamide chemical structure, C19H19ClN4O4, CAS 5535-16-0
6-Chloro-2-methyl-N-[(Z)-(3,4,5-trimethoxyphenyl)methylideneamino]imidazo[1,2-a]pyridine-3-carboxamide
CAS 5535-16-0C19H19ClN4O4
N-[(Z)-(2,5-Dimethoxyphenyl)methylideneamino]-2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide chemical structure, C19H20N4O3, CAS 5539-81-1
N-[(Z)-(2,5-Dimethoxyphenyl)methylideneamino]-2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide
CAS 5539-81-1C19H20N4O3
2,7-Dimethyl-N'-(2-nitrobenzylidene)imidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H15N5O3, CAS 5552-77-2
2,7-Dimethyl-N'-(2-nitrobenzylidene)imidazo[1,2-a]pyridine-3-carbohydrazide
CAS 5552-77-2C17H15N5O3
N-[(E)-Benzylideneamino]-2-methylimidazo[1,2-a]pyridine-3-carboxamide chemical structure, C16H14N4O, CAS 293299-27-1
N-[(E)-Benzylideneamino]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CAS 293299-27-1C16H14N4O
N-[(2,5-Dimethoxyphenyl)methylideneamino]-4,8-dimethyl-1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraene-9-carboxamide chemical structure, C19H20N4O3
N-[(2,5-Dimethoxyphenyl)methylideneamino]-4,8-dimethyl-1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraene-9-carboxamide
C19H20N4O3
N-[(Z)-(4-Ethoxyphenyl)methylideneamino]-2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide chemical structure, C19H20N4O2, CAS 331864-03-0
N-[(Z)-(4-Ethoxyphenyl)methylideneamino]-2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide
CAS 331864-03-0C19H20N4O2
N'-(4-Chlorobenzylidene)-2,7-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H15ClN4O, CAS 250382-18-4
N'-(4-Chlorobenzylidene)-2,7-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 250382-18-4C17H15ClN4O
N'-[(E)-(4-Methoxy-3-nitrophenyl)methylidene]-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H15N5O4, CAS 329719-69-9
N'-[(E)-(4-Methoxy-3-nitrophenyl)methylidene]-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 329719-69-9C17H15N5O4
N'-(2-Methoxybenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C18H18N4O2, CAS 351339-03-2
N'-(2-Methoxybenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 351339-03-2C18H18N4O2
N'-(4-Isopropylbenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C20H22N4O, CAS 351339-01-0
N'-(4-Isopropylbenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 351339-01-0C20H22N4O
N'-(3-Chlorobenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H15ClN4O, CAS 351339-02-1
N'-(3-Chlorobenzylidene)-2,6-dimethylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 351339-02-1C17H15ClN4O
6-Bromo-N'-(4-ethoxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C18H17BrN4O2, CAS 352561-86-5
6-Bromo-N'-(4-ethoxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 352561-86-5C18H17BrN4O2
N'-(2-Chlorobenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C16H13ClN4O, CAS 331426-50-7
N'-(2-Chlorobenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 331426-50-7C16H13ClN4O
2-Methyl-N'-(4-methylbenzylidene)imidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H16N4O, CAS 155699-17-5
2-Methyl-N'-(4-methylbenzylidene)imidazo[1,2-a]pyridine-3-carbohydrazide
CAS 155699-17-5C17H16N4O
N'-(4-Fluorobenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C16H13FN4O, CAS 155699-15-3
N'-(4-Fluorobenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS 155699-15-3C16H13FN4O
(E)-2-Methyl-N'-(1-(4-nitrophenyl)ethylidene)imidazo[1,2-a]pyridine-3-carbohydrazide chemical structure, C17H15N5O3, CAS 898061-42-2
(E)-2-Methyl-N'-(1-(4-nitrophenyl)ethylidene)imidazo[1,2-a]pyridine-3-carbohydrazide
CAS 898061-42-2C17H15N5O3