Murcko scaffold
Ring system with 3 rings and 26 atoms
29 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 26
- Chemicals
- 29
- With full pages
- 4
Scaffold SMILES
O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)N1CCCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide chemical structure, C21H26N2O3S, CAS 418784-59-5](/s/NCGLLSZUJLTXKA-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide
CAS 418784-59-5C21H26N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-chloro-2-methylphenyl)-4-methylbenzenesulfonamide chemical structure, C22H27ClN2O3S, CAS 428456-63-7](/s/OSCGZGACAGPJJG-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-chloro-2-methylphenyl)-4-methylbenzenesulfonamide
CAS 428456-63-7C22H27ClN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-methylphenyl)-4-methylsulfanylbenzenesulfonamide chemical structure, C22H28N2O3S2, CAS 398519-84-1](/s/ZUNFDOZKZRTOTF-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-methylphenyl)-4-methylsulfanylbenzenesulfonamide
CAS 398519-84-1C22H28N2O3S2
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dimethylphenyl)-4-methylbenzenesulfonamide chemical structure, C23H30N2O3S, CAS 367959-78-2](/s/UBFKSNQXYKVRCX-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dimethylphenyl)-4-methylbenzenesulfonamide
CAS 367959-78-2C23H30N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(5-chloro-2-methoxyphenyl)-4-methylbenzenesulfonamide chemical structure, C22H27ClN2O4S, CAS 367930-19-6](/s/QPQMCXPQZNNMDF-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(5-chloro-2-methoxyphenyl)-4-methylbenzenesulfonamide
CAS 367930-19-6C22H27ClN2O4S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-chlorophenyl)-4-methylbenzenesulfonamide chemical structure, C21H25ClN2O3S, CAS 428487-02-9](/s/WHOHZFWFMXZLEP-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-chlorophenyl)-4-methylbenzenesulfonamide
CAS 428487-02-9C21H25ClN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-fluorophenyl)-4-methylbenzenesulfonamide chemical structure, C21H25FN2O3S, CAS 333745-30-5](/s/FRUJTOZPZLAGTF-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-fluorophenyl)-4-methylbenzenesulfonamide
CAS 333745-30-5C21H25FN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3-bromophenyl)benzenesulfonamide chemical structure, C20H23BrN2O3S, CAS 428474-49-1](/s/URCLIGUFCYDRDS-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3-bromophenyl)benzenesulfonamide
CAS 428474-49-1C20H23BrN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)-4-methylbenzenesulfonamide chemical structure, C21H24Cl2N2O3S, CAS 428465-20-7](/s/CTTMXRDRRZKHAH-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)-4-methylbenzenesulfonamide
CAS 428465-20-7C21H24Cl2N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide chemical structure, C23H30N2O4S, CAS 428491-81-0](/s/JTKVECYWJBMGGI-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
CAS 428491-81-0C23H30N2O4S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]benzenesulfonamide chemical structure, C21H22ClF3N2O3S, CAS 501912-80-7](/s/AXXZFSZAYLPPEW-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]benzenesulfonamide
CAS 501912-80-7C21H22ClF3N2O3S
N-(2-Azepan-1-yl-2-oxoethyl)-N-(4-ethoxyphenyl)-4-methylbenzenesulfonamide
CAS 428494-87-5C23H30N2O4S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide chemical structure, C23H30N2O3S, CAS 426220-22-6](/s/UMXNSXHHRVCMLR-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide
CAS 426220-22-6C23H30N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3-chloro-4-methoxyphenyl)benzenesulfonamide chemical structure, C21H25ClN2O4S, CAS 333749-15-8](/s/GHNWXSZWNXPKQD-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3-chloro-4-methoxyphenyl)benzenesulfonamide
CAS 333749-15-8C21H25ClN2O4S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(2,5-dimethoxyphenyl)-3,4-dimethoxybenzenesulfonamide chemical structure, C24H32N2O7S, CAS 642996-54-1](/s/VREIGNWCDXGCCR-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(2,5-dimethoxyphenyl)-3,4-dimethoxybenzenesulfonamide
CAS 642996-54-1C24H32N2O7S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-bromophenyl)benzenesulfonamide chemical structure, C20H23BrN2O3S, CAS 312278-93-6](/s/LQVQMVQLKOUVBR-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-bromophenyl)benzenesulfonamide
CAS 312278-93-6C20H23BrN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-4-chloro-N-phenylbenzenesulfonamide chemical structure, C20H23ClN2O3S, CAS 625822-58-4](/s/YHTNEKHDOQBWKS-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-4-chloro-N-phenylbenzenesulfonamide
CAS 625822-58-4C20H23ClN2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-4-fluoro-N-(4-methoxyphenyl)benzenesulfonamide chemical structure, C21H25FN2O4S, CAS 701953-27-7](/s/ZMUSBVVPCUOHMR-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-4-fluoro-N-(4-methoxyphenyl)benzenesulfonamide
CAS 701953-27-7C21H25FN2O4S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dimethylphenyl)-3,4-dimethoxybenzenesulfonamide chemical structure, C24H32N2O5S, CAS 359638-30-5](/s/DCUBKDBKJCFJMU-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dimethylphenyl)-3,4-dimethoxybenzenesulfonamide
CAS 359638-30-5C24H32N2O5S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-4-methyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide chemical structure, C22H25F3N2O3S, CAS 426233-05-8](/s/DDWGWBKUHGIOOW-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-4-methyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
CAS 426233-05-8C22H25F3N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(2,3-dimethylphenyl)-4-methylbenzenesulfonamide chemical structure, C23H30N2O3S, CAS 527702-21-2](/s/QSBXTPVXGXQVKS-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(2,3-dimethylphenyl)-4-methylbenzenesulfonamide
CAS 527702-21-2C23H30N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)benzenesulfonamide chemical structure, C20H22Cl2N2O3S, CAS 428470-08-0](/s/MXKOPVRVTLGCNG-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)benzenesulfonamide
CAS 428470-08-0C20H22Cl2N2O3S
![N-[2-(Azepan-1-yl)-2-oxoethyl]-4-methyl-N-(4-methylphenyl)benzenesulfonamide chemical structure, C22H28N2O3S, CAS 428497-24-9](/s/ZXCFHVNPDUBCCL-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxoethyl]-4-methyl-N-(4-methylphenyl)benzenesulfonamide
CAS 428497-24-9C22H28N2O3S
![N-[2-(Azepan-1-yl)-2-oxo-ethyl]-N-(3-bromophenyl)-4-methyl-benzenesulfonamide chemical structure, C21H25BrN2O3S, CAS 6489-37-8](/s/DTKCKYRVJLIPFS-UHFFFAOYSA-N.svg)
N-[2-(Azepan-1-yl)-2-oxo-ethyl]-N-(3-bromophenyl)-4-methyl-benzenesulfonamide
CAS 6489-37-8C21H25BrN2O3S
- N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(3,4-dichlorophenyl)benzenesulfonamide708991-34-8C20H22Cl2N2O3S
- N-[2-(Azepan-1-yl)-2-oxoethyl]-4-chloro-N-(4-ethoxyphenyl)benzenesulfonamide663166-25-4C22H27ClN2O4S
- N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(5-chloro-2-methoxyphenyl)-4-methyl-3-nitrobenzenesulfonamide352558-72-6C22H26ClN3O6S
- N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-methoxyphenyl)-4-methyl-3-nitrobenzenesulfonamide333741-64-3C22H27N3O6S
- N-[2-(Azepan-1-yl)-2-oxoethyl]-N-(4-chlorophenyl)-3,4-dimethoxybenzenesulfonamide827008-78-6C22H27ClN2O5S