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Murcko scaffold

Ring system with 3 rings and 15 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
6
With full pages
3
Scaffold SMILES

c1coc(C2=NNC(c3cccs3)C2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1coc(C2=NNC(c3cccs3)C2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

3-(2-Furyl)-1-(methylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazole chemical structure, C12H12N2O3S2, CAS 511237-73-3
3-(2-Furyl)-1-(methylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazole
CAS 511237-73-3C12H12N2O3S2
4-(3-Furan-2-yl-5-thiophen-2-yl-4,5-dihydro-pyrazol-1-yl)-4-oxo-butyric acid chemical structure, C15H14N2O4S, CAS 799256-22-7
4-(3-Furan-2-yl-5-thiophen-2-yl-4,5-dihydro-pyrazol-1-yl)-4-oxo-butyric acid
CAS 799256-22-7C15H14N2O4S
2-Chloro-1-[3-(5-methylfuran-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one chemical structure, C14H13ClN2O2S, CAS 796084-56-5
2-Chloro-1-[3-(5-methylfuran-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one
CAS 796084-56-5C14H13ClN2O2S
2-Chloro-1-[3-(furan-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one chemical structure, C13H11ClN2O2S, CAS 796106-54-2
2-Chloro-1-[3-(furan-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one
CAS 796106-54-2C13H11ClN2O2S
1-(3-(5-Methylfuran-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone chemical structure, C14H14N2O2S, CAS 1384796-31-9
1-(3-(5-Methylfuran-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
CAS 1384796-31-9C14H14N2O2S
5-[3-(Furan-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-5-oxopentanoic acid chemical structure, C16H16N2O4S, CAS 1785765-28-7
5-[3-(Furan-2-yl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-5-oxopentanoic acid
CAS 1785765-28-7C16H16N2O4S