CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 11 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
23
With full pages
9
Scaffold SMILES

O=C1CCCC2=C1CC=CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC2=C1CC=CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

2-Amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C14H18N2O2, CAS 201424-86-4
2-Amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 201424-86-4C14H18N2O2
2-Amino-4-isobutyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C14H18N2O2, CAS 275360-58-2
2-Amino-4-isobutyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 275360-58-2C14H18N2O2
2-Amino-4-isopropyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C13H16N2O2, CAS 302785-66-6
2-Amino-4-isopropyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 302785-66-6C13H16N2O2
2-Amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3,4,4-tricarbonitrile chemical structure, C14H12N4O2, CAS 30404-08-1
2-Amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3,4,4-tricarbonitrile
CAS 30404-08-1C14H12N4O2
2-Amino-4,4,7,7-tetramethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C14H18N2O2, CAS 221049-69-0
2-Amino-4,4,7,7-tetramethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 221049-69-0C14H18N2O2
2-Amino-7,7-dimethyl-5-oxo-4-propan-2-yl-6,8-dihydro-4H-chromene-3-carbonitrile chemical structure, C15H20N2O2, CAS 164410-74-6
2-Amino-7,7-dimethyl-5-oxo-4-propan-2-yl-6,8-dihydro-4H-chromene-3-carbonitrile
CAS 164410-74-6C15H20N2O2
2-Amino-7,7-dimethyl-5-oxo-4-propyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C15H20N2O2, CAS 275360-56-0
2-Amino-7,7-dimethyl-5-oxo-4-propyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 275360-56-0C15H20N2O2
2-Amino-5,6,7,8-tetrahydro-4,7,7-trimethyl-5-oxo-4H-1-benzopyran-3-carbonitrile chemical structure, C13H16N2O2, CAS 221218-34-4
2-Amino-5,6,7,8-tetrahydro-4,7,7-trimethyl-5-oxo-4H-1-benzopyran-3-carbonitrile
CAS 221218-34-4C13H16N2O2
2-Amino-7,7-dimethyl-4-(2-methylpropyl)-5-oxo-6,8-dihydro-4H-chromene-3-carbonitrile chemical structure, C16H22N2O2, CAS 275360-53-7
2-Amino-7,7-dimethyl-4-(2-methylpropyl)-5-oxo-6,8-dihydro-4H-chromene-3-carbonitrile
CAS 275360-53-7C16H22N2O2
2-Amino-4-(sec-butyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C16H22N2O2, CAS 332045-36-0
2-Amino-4-(sec-butyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332045-36-0C16H22N2O2
2-Amino-7,7-dimethyl-5-oxo-4-(pentan-2-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C17H24N2O2, CAS 332052-10-5
2-Amino-7,7-dimethyl-5-oxo-4-(pentan-2-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332052-10-5C17H24N2O2
2-Amino-4-methyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C11H12N2O2, CAS 175603-75-5
2-Amino-4-methyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 175603-75-5C11H12N2O2
2-Amino-4-hexyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C18H26N2O2, CAS 332045-52-0
2-Amino-4-hexyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332045-52-0C18H26N2O2
2-Amino-4-heptyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C19H28N2O2, CAS 332045-56-4
2-Amino-4-heptyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332045-56-4C19H28N2O2
2-Amino-7,7-dimethyl-5-oxo-4-(pentan-3-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C17H24N2O2, CAS 332052-08-1
2-Amino-7,7-dimethyl-5-oxo-4-(pentan-3-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332052-08-1C17H24N2O2
2-Amino-5-oxo-4-pentan-2-yl-4,6,7,8-tetrahydrochromene-3-carbonitrile chemical structure, C15H20N2O2, CAS 332052-09-2
2-Amino-5-oxo-4-pentan-2-yl-4,6,7,8-tetrahydrochromene-3-carbonitrile
CAS 332052-09-2C15H20N2O2
2-Amino-4-[hydroxy(methoxy)methyl]-4,7,7-trimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C15H20N2O4, CAS 866157-69-9
2-Amino-4-[hydroxy(methoxy)methyl]-4,7,7-trimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 866157-69-9C15H20N2O4
2-Amino-4-heptyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C17H24N2O2, CAS 327971-32-4
2-Amino-4-heptyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 327971-32-4C17H24N2O2
2-Amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3,4,4-tricarbonitrile chemical structure, C12H8N4O2, CAS 30404-07-0
2-Amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3,4,4-tricarbonitrile
CAS 30404-07-0C12H8N4O2
2-Amino-5-oxo-4-(pentan-3-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C15H20N2O2, CAS 332052-07-0
2-Amino-5-oxo-4-(pentan-3-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332052-07-0C15H20N2O2
2-Amino-4-hexyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C16H22N2O2, CAS 332045-51-9
2-Amino-4-hexyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 332045-51-9C16H22N2O2
2-Amino-4-ethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile chemical structure, C12H14N2O2, CAS 476210-27-2
2-Amino-4-ethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS 476210-27-2C12H14N2O2
2-Methyl-4,6,7,8-tetrahydro-5H-1-benzopyran-5-one chemical structure, C10H12O2, CAS 91060-97-8
2-Methyl-4,6,7,8-tetrahydro-5H-1-benzopyran-5-one
CAS 91060-97-8C10H12O2