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Murcko scaffold

Ring system with 3 rings and 14 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
13
With full pages
5
Scaffold SMILES

c1ncc2c3c(sc2n1)CCCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc2c3c(sc2n1)CCCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine chemical structure, C11H13N3S, CAS 257284-83-6
6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine
CAS 257284-83-6C11H13N3S
3-Chloro-8-thia-4,6-diazatricyclo(7.5.0.0,2,7)tetradeca-1(9),2,4,6-tetraene chemical structure, C11H11ClN2S, CAS 40106-58-9
3-Chloro-8-thia-4,6-diazatricyclo(7.5.0.0,2,7)tetradeca-1(9),2,4,6-tetraene
CAS 40106-58-9C11H11ClN2S
2-(Methylsulfanyl)-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine chemical structure, C12H15N3S2, CAS 332904-10-6
2-(Methylsulfanyl)-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine
CAS 332904-10-6C12H15N3S2
Ethyl 2-((4-amino-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetate chemical structure, C15H19N3O2S2, CAS 372971-51-2
Ethyl 2-((4-amino-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetate
CAS 372971-51-2C15H19N3O2S2
2-(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-ylamino)ethanol chemical structure, C13H17N3OS, CAS 421569-60-0
2-(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-ylamino)ethanol
CAS 421569-60-0C13H17N3OS
4-Hydrazinyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine chemical structure, C11H14N4S, CAS 40106-59-0
4-Hydrazinyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine
CAS 40106-59-0C11H14N4S
4-Chloro-2-methyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine chemical structure, C12H13ClN2S, CAS 867311-51-1
4-Chloro-2-methyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine
CAS 867311-51-1C12H13ClN2S
5-(Chloromethyl)-8-thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2,4,6-tetraen-3-amine chemical structure, C12H14ClN3S, CAS 877964-68-6
5-(Chloromethyl)-8-thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2,4,6-tetraen-3-amine
CAS 877964-68-6C12H14ClN3S
6,7,8,9-Tetrahydro-N-pentyl-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine chemical structure, C16H23N3S, CAS 937648-00-5
6,7,8,9-Tetrahydro-N-pentyl-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine
CAS 937648-00-5C16H23N3S
N,N-Dimethyl-2-[(6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)oxy]-1-propanamine chemical structure, C16H23N3OS, CAS 832674-73-4
N,N-Dimethyl-2-[(6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)oxy]-1-propanamine
CAS 832674-73-4C16H23N3OS
(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-ylsulfanyl)acetonitrile chemical structure, C13H13N3S2, CAS 1019016-67-1
(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-ylsulfanyl)acetonitrile
CAS 1019016-67-1C13H13N3S2
Ethyl 6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl ether chemical structure, C13H16N2OS, CAS 1019015-76-9
Ethyl 6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl ether
CAS 1019015-76-9C13H16N2OS
1-[(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)thio]-2-propanone chemical structure, C14H16N2OS2, CAS 1019016-16-0
1-[(6,7,8,9-Tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)thio]-2-propanone
CAS 1019016-16-0C14H16N2OS2