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Murcko scaffold

4-[1-(2-Phenoxyethyl)benzimidazol-2-yl]-1-phenylpyrrolidin-2-one scaffold

132 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
132
With full pages
4
Scaffold SMILES

O=C1CC(c2nc3ccccc3n2CCOc2ccccc2)CN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-[1-(2-Phenoxyethyl)benzimidazol-2-yl]-1-phenylpyrrolidin-2-one page
Murcko scaffold O=C1CC(c2nc3ccccc3n2CCOc2ccccc2)CN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 132 chemicals

4-{1-[2-(2-Methylphenoxy)ethyl]benzimidazol-2-yl}-1-phenylpyrrolidin-2-one chemical structure, C26H25N3O2, CAS 694488-88-5
4-{1-[2-(2-Methylphenoxy)ethyl]benzimidazol-2-yl}-1-phenylpyrrolidin-2-one
CAS 694488-88-5C26H25N3O2
4-{1-[2-(4-Methylphenoxy)ethyl]-1H-1,3-benzodiazol-2-yl}-1-phenylpyrrolidin-2-one chemical structure, C26H25N3O2, CAS 694507-08-9
4-{1-[2-(4-Methylphenoxy)ethyl]-1H-1,3-benzodiazol-2-yl}-1-phenylpyrrolidin-2-one
CAS 694507-08-9C26H25N3O2
1-(4-Fluorophenyl)-4-[1-[2-(4-methoxyphenoxy)ethyl]benzimidazol-2-yl]pyrrolidin-2-one chemical structure, C26H24FN3O3, CAS 876713-00-7
1-(4-Fluorophenyl)-4-[1-[2-(4-methoxyphenoxy)ethyl]benzimidazol-2-yl]pyrrolidin-2-one
CAS 876713-00-7C26H24FN3O3
4-[1-(2-Phenoxyethyl)benzimidazol-2-yl]-1-phenylpyrrolidin-2-one chemical structure, C25H23N3O2, CAS 692747-00-5
4-[1-(2-Phenoxyethyl)benzimidazol-2-yl]-1-phenylpyrrolidin-2-one
CAS 692747-00-5C25H23N3O2
1-(4-Methoxyphenyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 877786-20-4
1-(4-Methoxyphenyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 877786-20-4C27H27N3O3
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one chemical structure, C26H24ClN3O3, CAS 586998-58-5
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one
CAS 586998-58-5C26H24ClN3O3
1-(m-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 874615-38-0
1-(m-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 874615-38-0C27H27N3O2
1-(3-Methoxyphenyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 850243-86-6
1-(3-Methoxyphenyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 850243-86-6C27H27N3O3
1-(2-Methoxyphenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C26H25N3O3, CAS 577763-27-0
1-(2-Methoxyphenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 577763-27-0C26H25N3O3
1-(3-Methoxyphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 850750-24-2
1-(3-Methoxyphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 850750-24-2C27H27N3O3
1-(p-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 845627-67-0
1-(p-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 845627-67-0C27H27N3O2
1-(3-Methoxyphenyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 850159-15-8
1-(3-Methoxyphenyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 850159-15-8C27H27N3O3
1-(2-Methoxyphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 586994-81-2
1-(2-Methoxyphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 586994-81-2C27H27N3O3
1-(p-Tolyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 845803-27-2
1-(p-Tolyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 845803-27-2C27H27N3O2
1-(o-Tolyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 845809-62-3
1-(o-Tolyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 845809-62-3C27H27N3O2
1-(3-Methylphenyl)-4-[1-(2-phenoxyethyl)benzimidazol-2-yl]pyrrolidin-2-one chemical structure, C26H25N3O2, CAS 877777-55-4
1-(3-Methylphenyl)-4-[1-(2-phenoxyethyl)benzimidazol-2-yl]pyrrolidin-2-one
CAS 877777-55-4C26H25N3O2
1-(o-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 846600-38-2
1-(o-Tolyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 846600-38-2C27H27N3O2
4-[1-[2-(4-Chlorophenoxy)ethyl]benzimidazol-2-yl]-1-(3-methoxyphenyl)pyrrolidin-2-one chemical structure, C26H24ClN3O3, CAS 862191-81-9
4-[1-[2-(4-Chlorophenoxy)ethyl]benzimidazol-2-yl]-1-(3-methoxyphenyl)pyrrolidin-2-one
CAS 862191-81-9C26H24ClN3O3
1-(p-Tolyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 845662-44-4
1-(p-Tolyl)-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 845662-44-4C27H27N3O2
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one chemical structure, C26H24ClN3O3, CAS 849921-73-9
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one
CAS 849921-73-9C26H24ClN3O3
1-(2-Methoxyphenyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O3, CAS 578755-24-5
1-(2-Methoxyphenyl)-4-(1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 578755-24-5C27H27N3O3
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one chemical structure, C26H24ClN3O2, CAS 848727-41-3
4-(1-(2-(4-Chlorophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one
CAS 848727-41-3C26H24ClN3O2
1-(o-Tolyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C27H27N3O2, CAS 848733-25-5
1-(o-Tolyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 848733-25-5C27H27N3O2
1-(2,4-Dimethylphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C28H29N3O2, CAS 847394-39-2
1-(2,4-Dimethylphenyl)-4-(1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 847394-39-2C28H29N3O2