Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 24 atoms

18 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 18
With full pages: 3

Scaffold SMILES

O=c1[nH]c(-c2ccccc2)nc2cn(-c3ccccc3)c(=O)nc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1[nH]c(-c2ccccc2)nc2cn(-c3ccccc3)c(=O)nc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

6-(4-Chlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione chemical structure, C18H12ClN5O2, CAS 865658-75-9

6-(4-Chlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione

CAS 865658-75-9C₁₈H₁₂ClN₅O₂

4-Imino-3,6-diphenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione chemical structure, C18H13N5O2, CAS 66482-88-0

4-Imino-3,6-diphenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione

CAS 66482-88-0C₁₈H₁₃N₅O₂

6-(4,5-Dimethoxy-2-nitrophenyl)-3-(4-chlorophenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C20H15ClN6O6, CAS 1274904-23-2

6-(4,5-Dimethoxy-2-nitrophenyl)-3-(4-chlorophenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1274904-23-2C₂₀H₁₅ClN₆O₆

6-(2-Hydroxy-3-methoxyphenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C20H14F3N5O4, CAS 1119391-74-0

6-(2-Hydroxy-3-methoxyphenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-74-0C₂₀H₁₄F₃N₅O₄

6-(2,4-Dichlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione chemical structure, C18H11Cl2N5O2, CAS 866019-00-3

6-(2,4-Dichlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione

CAS 866019-00-3C₁₈H₁₁Cl₂N₅O₂

6-(4-(Dimethylamino)phenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C21H17F3N6O2, CAS 1119391-72-8

6-(4-(Dimethylamino)phenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-72-8C₂₁H₁₇F₃N₆O₂

3-(4-Chlorophenyl)-4-imino-6-(2-nitrophenyl)-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione chemical structure, C18H11ClN6O4, CAS 1020252-00-9

3-(4-Chlorophenyl)-4-imino-6-(2-nitrophenyl)-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione

CAS 1020252-00-9C₁₈H₁₁ClN₆O₄

6-(2-Chloro-5-nitrophenyl)-3-(4-chlorophenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C18H10Cl2N6O4, CAS 1274903-28-4

6-(2-Chloro-5-nitrophenyl)-3-(4-chlorophenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1274903-28-4C₁₈H₁₀Cl₂N₆O₄

3-(4-Chlorophenyl)-4-imino-6-(4-methoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C19H14ClN5O3, CAS 379707-94-5

3-(4-Chlorophenyl)-4-imino-6-(4-methoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 379707-94-5C₁₉H₁₄ClN₅O₃

6-(2-Chlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione chemical structure, C18H12ClN5O2, CAS 866019-01-4

6-(2-Chlorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione

CAS 866019-01-4C₁₈H₁₂ClN₅O₂

4-Imino-3-(3-(trifluoromethyl)phenyl)-6-(3,4,5-trimethoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C22H18F3N5O5, CAS 1119391-73-9

4-Imino-3-(3-(trifluoromethyl)phenyl)-6-(3,4,5-trimethoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-73-9C₂₂H₁₈F₃N₅O₅

6-(4-Fluorophenyl)-4-imino-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C18H12FN5O2, CAS 1119391-90-0

6-(4-Fluorophenyl)-4-imino-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-90-0C₁₈H₁₂FN₅O₂

6-(3,4-Dimethoxyphenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C21H16F3N5O4, CAS 379708-00-6

6-(3,4-Dimethoxyphenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 379708-00-6C₂₁H₁₆F₃N₅O₄

6-(6-Chloro-2-fluorophenyl)-4-imino-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C18H11ClFN5O2, CAS 1119392-00-5

6-(6-Chloro-2-fluorophenyl)-4-imino-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119392-00-5C₁₈H₁₁ClFN₅O₂

3-(4-Chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C19H14ClN5O4, CAS 379707-96-7

3-(4-Chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-4-imino-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 379707-96-7C₁₉H₁₄ClN₅O₄

4-Imino-6-(4-(isopropyl)phenyl)-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C21H19N5O2, CAS 1119391-98-8

4-Imino-6-(4-(isopropyl)phenyl)-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-98-8C₂₁H₁₉N₅O₂

3-(4-Chlorophenyl)-4-imino-6-(3,4,5-trimethoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C21H18ClN5O5, CAS 1119391-58-0

3-(4-Chlorophenyl)-4-imino-6-(3,4,5-trimethoxyphenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 1119391-58-0C₂₁H₁₈ClN₅O₅

4-Imino-6-(2-methoxyphenyl)-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione chemical structure, C19H15N5O3, CAS 499197-57-8

4-Imino-6-(2-methoxyphenyl)-3-phenyl-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

CAS 499197-57-8C₁₉H₁₅N₅O₃