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Murcko scaffold

Ring system with 2 rings and 20 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)NN=CC=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NN=CC=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Methoxybenzeneacetic acid 2-(2-methyl-3-phenyl-2-propen-1-ylidene)hydrazide chemical structure, C19H20N2O2, CAS 355810-86-5
4-Methoxybenzeneacetic acid 2-(2-methyl-3-phenyl-2-propen-1-ylidene)hydrazide
CAS 355810-86-5C19H20N2O2
2-Hydroxy-N-[(E)-[(E)-3-(4-nitrophenyl)prop-2-enylidene]amino]-2-phenylacetamide chemical structure, C17H15N3O4, CAS 328937-94-6
2-Hydroxy-N-[(E)-[(E)-3-(4-nitrophenyl)prop-2-enylidene]amino]-2-phenylacetamide
CAS 328937-94-6C17H15N3O4
N-[(E)-[(E)-2-Methyl-3-phenylprop-2-enylidene]amino]-2-phenylacetamide chemical structure, C18H18N2O, CAS 343592-37-0
N-[(E)-[(E)-2-Methyl-3-phenylprop-2-enylidene]amino]-2-phenylacetamide
CAS 343592-37-0C18H18N2O
2-Hydroxy-2-phenyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C17H16N2O2, CAS 93331-40-9
2-Hydroxy-2-phenyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]acetamide
CAS 93331-40-9C17H16N2O2
N-[(E)-[(Z)-2-Bromo-3-phenylprop-2-enylidene]amino]-2-phenylacetamide chemical structure, C17H15BrN2O, CAS 341936-35-4
N-[(E)-[(Z)-2-Bromo-3-phenylprop-2-enylidene]amino]-2-phenylacetamide
CAS 341936-35-4C17H15BrN2O
N-[(E)-[(E)-3-(2-Nitrophenyl)prop-2-enylidene]amino]-2-phenylacetamide chemical structure, C17H15N3O3, CAS 341974-64-9
N-[(E)-[(E)-3-(2-Nitrophenyl)prop-2-enylidene]amino]-2-phenylacetamide
CAS 341974-64-9C17H15N3O3
2-Hydroxy-N'-[(1E,2E)-3-(3-nitrophenyl)prop-2-en-1-ylidene]-2-phenylacetohydrazide chemical structure, C17H15N3O4, CAS 330987-79-6
2-Hydroxy-N'-[(1E,2E)-3-(3-nitrophenyl)prop-2-en-1-ylidene]-2-phenylacetohydrazide
CAS 330987-79-6C17H15N3O4