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Murcko scaffold

3,4-Dihydro-2H-pyran-4-one scaffold

96 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
96
With full pages
16
Scaffold SMILES

O=C1C=COCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 3,4-Dihydro-2H-pyran-4-one page
Murcko scaffold O=C1C=COCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 96 chemicals

Butopyronoxyl chemical structure, C12H18O4, CAS 532-34-3
Butopyronoxyl
CAS 532-34-3C12H18O4
2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one chemical structure, C6H8O4, CAS 28564-83-2
2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one
CAS 28564-83-2C6H8O4
4H-Pyran-4-one, 2-ethyl-2,3-dihydro-3,5-dimethyl-6-(1-methyl-2-oxobutyl)-, (2S,3R)- chemical structure, C14H22O3, CAS 86797-89-9
4H-Pyran-4-one, 2-ethyl-2,3-dihydro-3,5-dimethyl-6-(1-methyl-2-oxobutyl)-, (2S,3R)-
CAS 86797-89-9C14H22O3
4H-Pyran-4-one, 2-ethyl-2,3-dihydro-6-((1S,2S)-2-hydroxy-1-methylbutyl)-3,5-dimethyl-, (2S,3R)- chemical structure, C14H24O3, CAS 86797-90-2
4H-Pyran-4-one, 2-ethyl-2,3-dihydro-6-((1S,2S)-2-hydroxy-1-methylbutyl)-3,5-dimethyl-, (2S,3R)-
CAS 86797-90-2C14H24O3
Stegobinone chemical structure, C13H20O3, CAS 110996-50-4
Stegobinone
CAS 110996-50-4C13H20O3
3,4-Dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylic acid chemical structure, C8H10O4, CAS 80866-93-9
3,4-Dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylic acid
CAS 80866-93-9C8H10O4
Ethyl 2,2-dimethyl-4-oxo-3,4-dihydro-2H-pyran-6-carboxylate chemical structure, C10H14O4, CAS 5464-36-8
Ethyl 2,2-dimethyl-4-oxo-3,4-dihydro-2H-pyran-6-carboxylate
CAS 5464-36-8C10H14O4
4H-Pyran-4-one, 5,6-dihydro-6,6-bis(trifluoromethyl)-2-methyl- chemical structure, C8H6F6O2, CAS 102129-09-9
4H-Pyran-4-one, 5,6-dihydro-6,6-bis(trifluoromethyl)-2-methyl-
CAS 102129-09-9C8H6F6O2
3-Hydroxy-4-oxo-2,3-dihydropyran-6-carbaldehyde chemical structure, C6H6O4, CAS 151391-61-6
3-Hydroxy-4-oxo-2,3-dihydropyran-6-carbaldehyde
CAS 151391-61-6C6H6O4
3,4-Dihydro-2H-pyran-4-one chemical structure, C5H6O2, CAS 84302-42-1
3,4-Dihydro-2H-pyran-4-one
CAS 84302-42-1C5H6O2
4H-Pyran-4-one, 6-ethyl-2,3-dihydro-2-methyl- chemical structure, C8H12O2, CAS 18781-76-5
4H-Pyran-4-one, 6-ethyl-2,3-dihydro-2-methyl-
CAS 18781-76-5C8H12O2
2-Methyl-5,6-dihydro-4-pyrone chemical structure, C6H8O2, CAS 22697-33-2
2-Methyl-5,6-dihydro-4-pyrone
CAS 22697-33-2C6H8O2
2-Ethoxy-2,3-dihydro-5-tetradecyl-6-(trifluoromethyl)-4H-pyran-4-one chemical structure, C22H37F3O3, CAS 164021-32-3
2-Ethoxy-2,3-dihydro-5-tetradecyl-6-(trifluoromethyl)-4H-pyran-4-one
CAS 164021-32-3C22H37F3O3
(S)-2-Methyl-2H-pyran-4(3H)-one chemical structure, C6H8O2, CAS 190912-15-3
(S)-2-Methyl-2H-pyran-4(3H)-one
CAS 190912-15-3C6H8O2
2,3-Dihydro-3,5-dihydroxy-(4H)-pyran-4-one chemical structure, C5H6O4, CAS 147235-40-3
2,3-Dihydro-3,5-dihydroxy-(4H)-pyran-4-one
CAS 147235-40-3C5H6O4
5-Hydroxy-6-methyl-3,4-dihydro-2H-pyran-4-one chemical structure, C6H8O3, CAS 38877-21-3
5-Hydroxy-6-methyl-3,4-dihydro-2H-pyran-4-one
CAS 38877-21-3C6H8O3
Ascopyrone P chemical structure, C6H8O4, CAS 68732-99-0
Ascopyrone P
CAS 68732-99-0C6H8O4
Erinapyrone B chemical structure, C7H10O3, CAS 146064-67-7
Erinapyrone B
CAS 146064-67-7C7H10O3
2H-Pyran-2-carboxylic acid, 3,4-dihydro-2-methyl-4-oxo-, ethyl ester chemical structure, C9H12O4, CAS 113122-96-6
2H-Pyran-2-carboxylic acid, 3,4-dihydro-2-methyl-4-oxo-, ethyl ester
CAS 113122-96-6C9H12O4
Erinapyrone A chemical structure, C7H10O3, CAS 146064-66-6
Erinapyrone A
CAS 146064-66-6C7H10O3
2-Methyl-3,4-dihydro-2H-pyran-4-one chemical structure, C6H8O2, CAS 19185-89-8
2-Methyl-3,4-dihydro-2H-pyran-4-one
CAS 19185-89-8C6H8O2
4H-Pyran-4-one, 2-butyl-2,3-dihydro- chemical structure, C9H14O2, CAS 159455-03-5
4H-Pyran-4-one, 2-butyl-2,3-dihydro-
CAS 159455-03-5C9H14O2
Hepialone chemical structure, C8H12O2, CAS 95833-18-4
Hepialone
CAS 95833-18-4C8H12O2
2,6-Dimethyl-3,4-dihydro-2H-pyran-4-one chemical structure, C7H10O2, CAS 16000-13-8
2,6-Dimethyl-3,4-dihydro-2H-pyran-4-one
CAS 16000-13-8C7H10O2